Human | UCA1 | 652995 | urothelial cancer associated 1 (non-protein coding) | Results from the present study suggested that UCA1 might play a pivotal role in bladder cancer progression and embryonic development |
Human | MIR101-2 | 406894 | | study proposes that the genomic loss of miR-101 in cancer leads to overexpression of EZH2 and concomitant dysregulation of epigenetic pathways, resulting in cancer progression |
Human | MIR101-1 | 406893 | | study proposes that the genomic loss of miR-101 in cancer leads to overexpression of EZH2 and concomitant dysregulation of epigenetic pathways, resulting in cancer progression |
Human | MTDH | 92140 | metadherin | AEG-1 protein is a valuable marker of breast cancer progression |
Human | SCAF1 | 58506 | SR-related CTD-associated factor 1 | Our results suggest that SRA1 is associated with cancer progression and may possibly be characterized as a new marker of unfavorable prognosis for ovarian cancer |
Human | SLURP1 | 57152 | secreted LY6/PLAUR domain containing 1 | SLURP-1 participates in the regulation of gut immune functions and motility, as well as possibly playing a role in colon carcinogenesis/cancer progression |
Human | EAF2 | 55840 | ELL associated factor 2 | U19 is growth inhibitory and tumor suppressive and that the disruption of androgen-dependent growth inhibition via U19 down-regulation is commonly associated with prostate cancer progression |
Human | TRPV6 | 55503 | transient receptor potential cation channel, subfamily V, member 6 | there is growing evidence that transcriptional regulation of TRPV6 in certain tissues undergoing malignant transformation, such as prostate cancer, is linked to cancer progression--{REVIEW} |
Human | STYK1 | 55359 | serine/threonine/tyrosine kinase 1 | The regulation of STYK1/NOK is achieved independent of ERalpha and suggests further investigation to the relevance of this kinase in breast cancer progression |
Human | ADI1 | 55256 | acireductone dioxygenase 1 | ADI1 may check prostate cancer progression through apoptosis by an activity that does not require metal binding |
Human | FXYD5 | 53827 | FXYD domain containing ion transport regulator 5 | Dysadherin may play an important role in breast cancer progression by promoting invasion Recent work that has provided insights into possible mechanisms of action of dysadherin in the cancer progression process was reviewed |
Human | PARVB | 29780 | parvin, beta | Parvin-beta might influence breast cancer progression |
Human | LSM1 | 27257 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) | Results suggest that LSm-1/CaSm functions as an oncogene in the promotion of cellular transformation and cancer progression Lsm1 is deeply involved in prostate cancer progression through its down-regulation, independent of any gene mutation |
Human | DKK3 | 27122 | dickkopf WNT signaling pathway inhibitor 3 | Loss of Dkk-3 expression resulting in impairment of glandular structure and uncontrolled prostate epithelial cell (PrEC) proliferation, both of which are crucial for prostate cancer progression |
Human | PELP1 | 27043 | proline, glutamate and leucine rich protein 1 | Data suggest that PELP1 is a potential oncogene, that its expression is deregulated during cancer progression, and that PELP1 may play a role in oncogenesis PELP1 functions as a molecular adaptor, coupling FHL2 with nuclear receptors, and PELP1-FHL2 interactions may have a role in prostate cancer progression |
Human | HINFP | 25988 | histone H4 transcription factor | the transcriptional silencing of the 14-3-3sigma gene is caused by promoter CpG island methylation associated with MBD2, which may play an important role in prostate cancer progression during the invasive and metastatic stages of the disease |
Human | COBRA1 | 25920 | | COBRA1 and BRCA1 may engage in common gene regulatory pathways to suppress breast cancer progression |
Human | KLK5 | 25818 | kallikrein-related peptidase 5 | hK5 is able to internally cleave insulin-like growth factor-binding proteins 1, 2, 3, 4, and 5, but not 6, suggesting that it might be involved in prostate cancer progression through growth factor regulation |
Human | SPDEF | 25803 | SAM pointed domain containing ETS transcription factor | these results for the first time show frequent increased expression of PDEF protein in breast and prostate tumors and support a role for PDEF in breast and prostate cancer progression |
Human | AMACR | 23600 | alpha-methylacyl-CoA racemase | AMACR expression is significantly associated with prostate cancer progression and suggests that not all surrogate end points may be optimal to define biomarkers of aggressive prostate cancer |
Human | SCRIB | 23513 | scribbled planar cell polarity protein | Down-regulation of scrib is associated with colon cancer progression |
Human | EPB41L3 | 23136 | erythrocyte membrane protein band 4.1-like 3 | suggest a more general role for Protein 4.1B as a negative regulator of cancer progression to metastatic disease |
Human | RRP1B | 23076 | ribosomal RNA processing 1B | These data suggest that RRP1B may be a novel susceptibility gene for breast cancer progression and metastasis |
Human | PHLDA1 | 22822 | pleckstrin homology-like domain, family A, member 1 | Reduced PHLDA1 expression is important in breast cancer progression and could serve as useful prognostic marker of disease outcome |
Human | KLK8 | 11202 | kallikrein-related peptidase 8 | Expression of hK8 is increased during the development of ovarian cancer and down-regulated during ovarian cancer progression |