Human | KCNRG | 283518 | potassium channel regulator | the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene |
Human | SEPT10 | 151011 | septin 10 | Lack of SEPT10 transcript is associated with B-cell chronic lymphocytic leukemia |
Human | FCRL3 | 115352 | Fc receptor-like 3 | Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia |
Human | PEG10 | 23089 | paternally expressed 10 | PEG10 represents a novel marker in B-cell chronic lymphocytic leukemia |
Human | TCL1A | 8115 | T-cell leukemia/lymphoma 1A | The results indicate that Tcl1 overexpression causes B cell chronic lymphocytic leukemia by directly enhancing NF-kappaB activity and inhibiting AP-1 |
Human | CXCR4 | 7852 | chemokine (C-X-C motif) receptor 4 | Factors other than alteration in SDF-1/CXCR4 chemokine system must account for marrow infiltration of neoplastic cells in B-cell chronic lymphocytic leukemia |
Human | ZAP70 | 7535 | zeta-chain (TCR) associated protein kinase 70kDa | murine leukemia model with many similarities to human ZAP-70+ B cell chronic lymphocytic leukemia when human B cells are transplanted into NOD/SCID mice |
Human | VEGFA | 7422 | vascular endothelial growth factor A | VEGF overexpression is associated with B-cell chronic lymphocytic leukemia |
Human | TP73 | 7161 | tumor protein p73 | Overexpression of the p73 is associated with B-cell chronic lymphocytic leukaemia |
Human | TP53 | 7157 | tumor protein p53 | although p53 mutation is relatively rare, the type and distribution of mutations in low-grade B-cell malignancy patients does not differ significantly from other forms of cancer p53 is part of the survival pathway induced by integrin alpha4beta1 ligation and has a role in B-cell chronic lymphocytic leukemia drug resistance |
Human | TERT | 7015 | telomerase reverse transcriptase | study identifies hTERT-RNA level as a new prognostic marker in B-cell chronic lymphocytic leukemia, and may be used to identify previously unrecognized patient groups with the same IgVH mutation status and different disease outcomes |
Human | TRG@ | 6965 | | molecular diversity in peripheral blood (t cells) from patients with b-cell chronic lymphocytic leukemia (TCR gamma-delta) |
Human | TRD@ | 6964 | | molecular diversity in peripheral blood (t cells) from patients with b-cell chronic lymphocytic leukemia (TCR gamma-delta) |
Human | TRB@ | 6957 | | Title:Leukemia-associated monoclonal and oligoclonal TCR-BV use in patients with B-cell chronic lymphocytic leukemia.|Association:Not Found|Conclusion:Not Found |
Human | SDC1 | 6382 | syndecan 1 | syndecan-1 may have a role in progression of B-cell chronic lymphocytic leukemia |
Human | CCL21 | 6366 | chemokine (C-C motif) ligand 21 | CCL21 significantly increased B-cell chronic lymphocytic leukemia MMP-9 production |
Human | EIF2AK2 | 5610 | eukaryotic translation initiation factor 2-alpha kinase 2 | Loss of PKR activity may contribute to the formation and/or maintenance of B-cell chronic lymphocytic leukemia |
Human | NT5E | 4907 | 5'-nucleotidase, ecto (CD73) | Review: Ecto-5'-nucleotidase in B-cell chronic lymphocytic leukemia |
Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | MMP-9 is physiologically regulated by alpha4beta1 integrin and CXCL12 and plays a key role in cell invasion and transendothelial migration in b-cell chronic lymphocytic leukemia MMP-9 is involved in B-cell chronic lymphocytic leukemia nodal infiltration |
Human | MCL1 | 4170 | myeloid cell leukemia sequence 1 (BCL2-related) | High MCL-1 expression is associated with B-cell chronic lymphocytic leukemia |
Human | LPL | 4023 | lipoprotein lipase | lipoprotein lipase and dystrophin have roles in survival in B-cell chronic lymphocytic leukemia lipoprotein lipase has a role in B-cell chronic lymphocytic leukemia |
Human | JAK2 | 3717 | Janus kinase 2 | a mutation of Janus kinase 2 is not responsible for B cell chronic lymphocytic leukemia developing in a patient with Polycythemia Vera |
Human | ITGB1 | 3688 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | integrin alpha4beta1 is induced by p53 and has a role in B-cell chronic lymphocytic leukemia drug resistance |
Human | ITGA4 | 3676 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | integrin alpha4beta1 is induced by p53 and has a role in B-cell chronic lymphocytic leukemia drug resistance |
Human | IFNG | 3458 | interferon, gamma | findings indicate that T-cell populations rather than malignant B cells are the source of interferon-gamma in B-cell chronic lymphocytic leukemia patients |