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Details
Link-It Detail - Disease - Peripheral Arterial Disease
Debug Stats
  • ### Total Build Time: 26 ms 49.108 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 316 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 997 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 2.784 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 12.893 KB
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 30.369 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Peripheral Arterial Disease C1704436
Peripheral Arterial Diseases
Definition (1)
Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Peripheral Vascular Diseases C0085096
img Atherosclerosis C0004153
Ancestral Roots
RootRoot Plus OneDepthParent
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Peripheral Vascular Diseases C0085096
img Cardiovascular Diseases C0007222img Vascular Diseases C00423736img Atherosclerosis C0004153
Relationships (45)

Relation Types:
diso_​to_​anat : 13
diso_​to_​chem : 3
diso_​to_​diso : 25
diso_​to_​phen : 1
diso_​to_​phys : 3


Relationships:
none : 37
is_​associated_​anatomic_​site_​of : 2
mapped_​to : 1
permuted_​term_​of : 1
related_​to : 4
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO132img Complication Aspects C1171258
DISO_to_ANAT95img Lower Extremity C0023216
DISO_to_ANAT93img In Blood C0005768
DISO_to_DISO69img Ischemia C0022116
DISO_to_ANAT68img Femoral Artery C0015801
DISO_to_PHYS66img ABI C1328319
DISO_to_DISO55img Intermittent Claudication C0021775
DISO_to_ANAT39img Popliteal Artery C0032649
DISO_to_ANAT38img Leg C1140621
DISO_to_DISO38img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO33img Cardiovascular Diseases C0007222
DISO_to_DISO28img Atherosclerosis C0004153
DISO_to_DISO27img Coronary Artery Disease C1956346
DISO_to_DISO27img Diabetic Angiopathies C0011875
DISO_to_ANAT26img Muscle, Skeletal C0242692
DISO_to_PHEN23img genetic aspects C0017399
DISO_to_DISO22img Arterial Occlusive Diseases C0003838
DISO_to_PHYS19img Neovascularization, Physiologic C0282546
DISO_to_ANAT16img Endothelium, Vascular C0014261
DISO_to_ANAT15img Iliac Artery C0020887
DISO_to_DISO15img Kidney Failure, Chronic C0022661
DISO_to_ANAT14img Arteries C0003842
DISO_to_CHEM14img Cardiovascular Agents C0007220
DISO_to_DISO14img Diabetes Mellitus C0011849
DISO_to_PHYS14img Blood Pressure C0005823
Genes (30)

Species:
human : 30
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanVKORC179001vitamin K epoxide reductase complex, subunit 1
img GENERIF, Score=1000, Pubmed Id: 18449434, UMLKSK CUI: C1704436
HumanP2RY1264805purinergic receptor P2Y, G-protein coupled, 12
img GENERIF, Score=976, Pubmed Id: 15933261, UMLKSK CUI: C1704436
img GAD, Score=1000, Pubmed Id: 14662702, UMLKSK CUI: C1704436
HumanUGT1A154658UDP glucuronosyltransferase 1 family, polypeptide A1
img GENERIF, Score=1000, Pubmed Id: 18375480, UMLKSK CUI: C1704436
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=1000, Pubmed Id: 17112494, UMLKSK CUI: C1704436
HumanVCAM17412vascular cell adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 18787016, UMLKSK CUI: C1704436
HumanSPP16696secreted phosphoprotein 1
img GENERIF, Score=1000, Pubmed Id: 18388057, UMLKSK CUI: C1704436
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=1000, Pubmed Id: 15203564, UMLKSK CUI: C1704436
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=1000, Pubmed Id: 18538667, UMLKSK CUI: C1704436
HumanPLTP5360phospholipid transfer protein
img GENERIF, Score=1000, Pubmed Id: 17553507, UMLKSK CUI: C1704436
HumanENPP15167ectonucleotide pyrophosphatase/phosphodiesterase 1
img GENERIF, Score=1000, Pubmed Id: 18389334, UMLKSK CUI: C1704436
HumanNPPB4879natriuretic peptide B
img GENERIF, Score=1000, Pubmed Id: 17112494, UMLKSK CUI: C1704436
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=1000, Pubmed Id: 17367796, UMLKSK CUI: C1704436
HumanMTTP4547microsomal triglyceride transfer protein
img GENERIF, Score=1000, Pubmed Id: 18325332, UMLKSK CUI: C1704436
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
img GENERIF, Score=923, Pubmed Id: 16274479, UMLKSK CUI: C1704436
HumanLPA4018lipoprotein, Lp(a)
img GENERIF, Score=1000, Pubmed Id: 17942087, UMLKSK CUI: C1704436
HumanLIPC3990lipase, hepatic
img GENERIF, Score=1000, Pubmed Id: 18413186, UMLKSK CUI: C1704436
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 18787016, UMLKSK CUI: C1704436
HumanHFE3077hemochromatosis
img GENERIF, Score=976, Pubmed Id: 15175819, UMLKSK CUI: C1704436
HumanSERPIND13053serpin peptidase inhibitor, clade D (heparin cofactor), member 1
img GENERIF, Score=976, Pubmed Id: 15543340, UMLKSK CUI: C1704436
HumanGGT12678gamma-glutamyltransferase 1
img GENERIF, Score=976, Pubmed Id: 18037420, UMLKSK CUI: C1704436
HumanF72155coagulation factor VII (serum prothrombin conversion accelerator)
img GENERIF, Score=1000, Pubmed Id: 17938795, UMLKSK CUI: C1704436
HumanF52153coagulation factor V (proaccelerin, labile factor)
img GENERIF, Score=1000, Pubmed Id: 15304039, UMLKSK CUI: C1704436
HumanF22147coagulation factor II (thrombin)
img GENERIF, Score=1000, Pubmed Id: 15304039, UMLKSK CUI: C1704436
HumanACE1636angiotensin I converting enzyme
img GENERIF, Score=1000, Pubmed Id: 12208484, UMLKSK CUI: C1704436
HumanCX3CR11524chemokine (C-X3-C motif) receptor 1
img GENERIF, Score=756, Pubmed Id: 12535747, UMLKSK CUI: C1704436
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1704436Peripheral Arterial Disease0self