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Genes (22)
Species: human : 22 | |
Human | SLC34A3 | 142680 | solute carrier family 34 (type II sodium/phosphate contransporter), member 3 | Decreased tubular maximum for phosphate reabsorption per glomerular filtration rate (TmP/GFR) | Human | ADIPOR2 | 79602 | adiponectin receptor 2 | Lower AdipoR after kidney transplantation may be secondary to immunosuppression and/or an improvement in glomerular filtration rate and the uremic milieu | Human | RETN | 56729 | resistin | In adults with hypertension, higher circulating resistin levels were associated with a lower estimated glomerular filtration rate and with increased urine albumin:creatinine ratio in the presence of concomitant diabetes | Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | serum ghrelin was inversely correlated with body mass index and with glomerular filtration rate | Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | results show unexpected positive correlations between leptin and insulin, leptin and adiponectin, a weak inverse relationship between adiponectin and glomerular filtration rate | Human | SOCS3 | 9021 | suppressor of cytokine signaling 3 | monocyte SOCS3 correlated with glomerular filtration rate, urea and diastolic blood pressure | Human | FGF23 | 8074 | fibroblast growth factor 23 | Decreased tubular maximum for phosphate reabsorption per glomerular filtration rate (TmP/GFR) | Human | NPHS2 | 7827 | nephrosis 2, idiopathic, steroid-resistant (podocin) | No significant association of the relatively rare R229Q variant and urinary albumin-creatinine ratio or estimated glomerular filtration rate was found in either white or black individuals | Human | VIM | 7431 | vimentin | The interstitial vimentin immunopositivity correlated with sclerotic/fibrotic lesions (interstitial fibrosis, tubular atrophies, vascular hyalinosis/fibrosis, chronicity index), and negatively with glomerular filtration rate | Human | TGFB1 | 7040 | transforming growth factor, beta 1 | The TGFbeta immunopositivity correlated with sclerotic/fibrotic lesions (interstitial fibrosis, tubular atrophies, vascular hyalinosis/fibrosis, chronicity index), and negatively with glomerular filtration rate | Human | PTGDS | 5730 | prostaglandin D2 synthase 21kDa (brain) | Data confirm the potential of Beta-trace protein as an endogenous Glomerular Filtration Rate marker in children Study performed in patients with kidney function ranging from normal to advanced renal failure suggests that serum beta-trace protein is an indicator of impaired glomerular filtration rate | Human | PHEX | 5251 | phosphate regulating endopeptidase homolog, X-linked | Decreased tubular maximum for phosphate reabsorption per glomerular filtration rate (TmP/GFR) | Human | NPPB | 4879 | natriuretic peptide B | Renal function correlates weakly with BNP and influences the optimal cut point for BNP, particularly in those with an estimated glomerular filtration rate less than 60 mL/min/1.73 m2 | Human | MMP2 | 4313 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | the activity of MMP-2 in the internal mammary artery is correlated with age, hypertension, diabetes and estimated glomerular filtration rate | Human | LEP | 3952 | leptin | results show unexpected positive correlations between leptin and insulin, leptin and adiponectin, a weak inverse relationship between adiponectin and glomerular filtration rate | Human | LCN2 | 3934 | lipocalin 2 | both serum NGAL and urinary NGAL were correlated with serum creatinine and, inversely, with residual glomerular filtration rate | Human | HMGB1 | 3146 | high mobility group box 1 | Data show that High Mobility Group Box Protein-1 (HMGB-1) is elevated significantly in chronic kidney disease patients and correlates with glomerular filtration rate as well as with markers of inflammation and malnutrition | Human | ACE | 1636 | angiotensin I converting enzyme | The rate of glomerular filtration rate decline does not correlate with the baseline urinary ACE expression | Human | CST3 | 1471 | cystatin C | Suggest that the serum levels of cystatin C are not always a reliable marker of the glomerular filtration rate in patients with a malignancy A more sensitive serum marker than creatinine of glomerular filtration rate fter kidney transplantation Creatinine measurement is cheaper and glomerular filtration rate is preferred to cystatin C levels in kidney donors May be a better marker of glomerular filtration rate in IDDM than creatinine A valid serum marker for glomerular filtration rate in renal transplantation Modification of Diet in Renal Disease (MDRD) is equivalent to cystatin C measurement as a measure of glomerular filtration rate Serum creatinine levels are lower in malnourished children and lead to overestimation of glomerular filtration rate, but cystatin C levels are unaffected Increased urinary cystatin C reflects structural and functional renal tubular impairment independent of glomerular filtration rate Linkage analysis of renal function, measured as glomerular filtration rate (GFR), in 63 extended families with multiple members with type 2 diabetes estimated from serum concentrations of cystatin C Cystatin C is an endogenous marker of glomerular filtration rate in kidney transplantation patients The comparisons show that differences in patient selections have a strong impact on the agreement between cystatin C and MDRD estimated glomerular filtration rate | Human | APOE | 348 | apolipoprotein E | Apolipoprotein E gene polymorphism has a role in hypercholesterolemia and type 2 diabetes, and affects glomerular filtration rate Polymorphisms of ApoE, independent of gender or other known factors, may affect serum creatinine levels and predict glomerular filtration rate in healthy persons | Human | AGT | 183 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Low-glomerular filtration rate cirrhotic patients had worse survival rate associated with more severe contraction of effective arterial blood volume, higher active renin /angiotensin II ratio and lower angiotensin-converting enzyme levels AGT expression in kidney proximal tubules adapts in the long-term to changes in glomerular filtration rate | Human | ADD1 | 118 | adducin 1 (alpha) | The present study shows that the Trp460Trp genotype of the alpha-adducin gene is significantly associated with reduced renal plasma flow and glomerular filtration rate |
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