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Details
Link-It Detail - Disease - IPMN
Debug Stats
  • ### Total Build Time: 169 ms 24.752 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 306 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 752 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=132 ms Completed: 132 ms rowSize= 15.219 KB
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 7.291 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.139 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
IPMN C1518869
Definition (1)
A usually slow-growing epithelial neoplasm with ductal differentiation that arises from the exocrine pancreas and grows mostly within the pancreatic ducts. Grossly, it is characterized by the presence of intraductal masses. Morphologically, there is proliferation of mucin-producing cells within the pancreatic ducts, intraductal accumulation of mucin, and a papillary growth pattern. It may be associated with the presence of an invasive carcinoma. It usually occurs in older patients. Signs and symptoms include epigastric pain, weight loss, jaundice, chronic pancreatitis, and diabetes mellitus.
Relationships (36)

Relation Types:
diso_​to_​anat : 10
diso_​to_​diso : 26


Relationships:
is_​abnormal_​cell_​of_​disease : 3
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 5
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 8
may_​be_​associated_​disease_​of_​disease : 2
may_​be_​cytogenetic_​abnormality_​of_​disease : 3
may_​be_​finding_​of_​disease : 3
may_​be_​molecular_​abnormality_​of_​disease : 3
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_associated_anatomic_site_ofimg Pancreas C0030274
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Pancreas, Exocrine C0553695
DISO_to_DISOmay_be_finding_of_diseaseimg Abdominal Pain C0000737
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg B-RAF Gene Mutation C1511021
DISO_to_DISOmay_be_finding_of_diseaseimg Body Weight decreased C0043096
DISO_to_DISOis_finding_of_diseaseimg Cystic Change C1511605
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Diabetes Mellitus C0011849
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOisaimg IOPN C2987197
DISO_to_DISOmay_be_finding_of_diseaseimg Icterus C0022346
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg Inactivation of p53 Tumor-Suppressor Gene C1515171
DISO_to_DISOis_finding_of_diseaseimg Intraductal Lesion C1881241
DISO_to_DISOisaimg Intraductal Papillary-Mucinous Neoplasm of Pancreas with Moderate Dysplasia C1335305
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg KRAS Gene Mutation C1517649
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Loss of Chromosome 17p C1517965
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Loss of Chromosome 18q C1517969
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Loss of Chromosome 9p C1517994
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanCLDN19076claudin 1
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1518869
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1518869
HumanMUC5AC4586mucin 5AC, oligomeric mucus/gel-forming
img NCI, Score=801, Pubmed Id: 15841035, UMLKSK CUI: C1518869
HumanCLDN41364claudin 4
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1518869
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1518869
HumanCDX21045caudal type homeobox 2
img GENERIF, Score=1000, Pubmed Id: 15782100, UMLKSK CUI: C1518869
HumanAKT1207v-akt murine thymoma viral oncogene homolog 1
img NCI, Score=801, Pubmed Id: 12657951, UMLKSK CUI: C1518869
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1518869IPMN0self