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Details
Link-It Detail - Disease - Oxidative Stress Induction
Debug Stats
  • ### Total Build Time: 38 ms 7.150 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 550 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=10 ms Completed: 10 ms rowSize= 1.270 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 3.771 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Disease (1)
Oxidative Stress Induction C1518761
Definition (1)
Oxidative Stress Induction involves initiation of activities that induce a disturbance in the pro-oxidant/antioxidant balance, leading to disruption of cell function by superoxide and other free radicals through damage to DNA bases, protein oxidation products, and lipid peroxidation products. Not synonymous with hypoxia or hyperoxia, oxidative stress promotes a range of degenerative disorders.
Relationships (1)

Relation Types:
diso_​to_​chem : 1


Relationships:
chemical_​or_​drug_​has_​physiologic_​effect : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEMchemical_or_drug_has_physiologic_effectimg 2-Amino-4-(S-butylsulfonimidoyl) Butanoic Acid C0054252
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanNFKB14790nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
img GENERIF, Score=904, Pubmed Id: 12958623, UMLKSK CUI: C1518761
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=904, Pubmed Id: 12958623, UMLKSK CUI: C1518761
HumanDDIT31649DNA-damage-inducible transcript 3
img GENERIF, Score=923, Pubmed Id: 18394432, UMLKSK CUI: C1518761
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1518761Oxidative Stress Induction0self