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Details
Link-It Detail - Disease - PPC
Debug Stats
  • ### Total Build Time: 12 ms 16.692 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 304 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 692 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=5 ms Completed: 5 ms rowSize= 9.592 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 4.920 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.138 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
PPC C1514428
Definition (1)
A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement.
Relationships (18)

Relation Types:
diso_​to_​anat : 10
diso_​to_​diso : 8


Relationships:
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 1
may_​be_​molecular_​abnormality_​of_​disease : 4
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Abdominal Cavity C0230168
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Peritoneum C0031153
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg BRCA1 Gene Inactivation C1511023
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg EGFR Gene Activation C1512116
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg ERBB2 Gene Amplification C1512127
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg Inactivation of p53 Tumor-Suppressor Gene C1515171
DISO_to_DISOis_finding_of_diseaseimg Primary Lesion C1402294
DISO_to_DISOisaimg Primary Peritoneal Serous Adenocarcinoma C1514429
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanKLK105655kallikrein-related peptidase 10
img NCI, Score=801, Pubmed Id: 12821340, UMLKSK CUI: C1514428
HumanMUC44585mucin 4, cell surface associated
img GENERIF, Score=923, Pubmed Id: 18008338, UMLKSK CUI: C1514428
HumanCAV1857caveolin 1, caveolae protein, 22kDa
img NCI, Score=801, Pubmed Id: 11863219, UMLKSK CUI: C1514428
HumanBRCA1672breast cancer 1, early onset
img GENERIF, Score=988, Pubmed Id: 14615451, UMLKSK CUI: C1514428
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1514428PPC0self