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Details
Link-It Detail - Disease - Adenoma, Oxyphilic
Debug Stats
  • ### Total Build Time: 18 ms 51.988 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 381 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 532 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 543 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.492 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 13.904 KB
  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 33.800 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Adenoma, Oxyphilic C1510502
Oxyphilic Adenoma
Definition (1)
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Adenoma C0001430
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Adenoma C0001430
Relationships (49)

Relation Types:
diso_​to_​anat : 9
diso_​to_​chem : 2
diso_​to_​diso : 36
diso_​to_​phen : 2


Relationships:
none : 31
is_​abnormal_​cell_​of_​disease : 4
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 3
isa : 4
mapped_​to : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO142img Kidney Neoplasm C0022665
DISO_to_DISO121img Kidney Neoplasm C0022665
DISO_to_DISO105img Thyroid Neoplasm C0040136
DISO_to_DISO86img Carcinoma, Renal Cell C0007134
DISO_to_DISO70img Thyroid Neoplasm C0040136
DISO_to_PHEN52img genetic aspects C0017399
DISO_to_DISO48img Carcinoma, Renal Cell C0007134
DISO_to_PHEN45img genetic aspects C0017399
DISO_to_DISO28img MULTIPLE PRIMARY NEOPL C0027663
DISO_to_DISO27img Carcinoma, Papillary C0007133
DISO_to_DISO27img Complication Aspects C1171258
DISO_to_DISO23img Adrenal Cortex Neoplasms C0001618
DISO_to_DISO23img NEOPL PAROTID C0030581
DISO_to_CHEM21img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO18img Adenocarcinoma, Follicular C0206682
DISO_to_DISO18img Complication Aspects C1171258
DISO_to_DISO17img MULTIPLE PRIMARY NEOPL C0027663
DISO_to_DISO15img NEOPL PAROTID C0030581
DISO_to_CHEM14img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO13img Adrenal Cortex Neoplasms C0001618
DISO_to_DISO12img Adenocarcinoma, Follicular C0206682
DISO_to_DISO12img Adrenal Gland Neoplasms C0001624
DISO_to_DISO12img Pituitary Neoplasms C0032019
DISO_to_DISO11img Carcinoma, Papillary C0007133
DISO_to_ANAT10img Cells, Oxyphil C0949666
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanPROM2150696prominin 2
img GENERIF, Score=861, Pubmed Id: 17145811, UMLKSK CUI: C1510502
HumanMAL2114569mal, T-cell differentiation protein 2 (gene/pseudogene)
img GENERIF, Score=861, Pubmed Id: 17145811, UMLKSK CUI: C1510502
HumanESRP154845epithelial splicing regulatory protein 1
img GENERIF, Score=861, Pubmed Id: 17145811, UMLKSK CUI: C1510502
HumanNDUFA1351079NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
img NCI, Score=801, Pubmed Id: 15841082, UMLKSK CUI: C1510502
img NCI, Score=801, Pubmed Id: 15841082, UMLKSK CUI: C1510502
HumanANKRD226287ankyrin repeat domain 2 (stretch responsive muscle)
img GENERIF, Score=1000, Pubmed Id: 17206105, UMLKSK CUI: C1510502
HumanPPRC123082peroxisome proliferator-activated receptor gamma, coactivator-related 1
img GENERIF, Score=861, Pubmed Id: 14550271, UMLKSK CUI: C1510502
HumanAP1M210053adaptor-related protein complex 1, mu 2 subunit
img GENERIF, Score=861, Pubmed Id: 17145811, UMLKSK CUI: C1510502
HumanCLDN89073claudin 8
img GENERIF, Score=1000, Pubmed Id: 18799195, UMLKSK CUI: C1510502
HumanNCOA48031nuclear receptor coactivator 4
img NCI, Score=801, Pubmed Id: 14668719, UMLKSK CUI: C1510502
HumanTPO7173thyroid peroxidase
img NCI, Score=801, Pubmed Id: 15116324, UMLKSK CUI: C1510502
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 2465910, UMLKSK CUI: C1510502
HumanS100A16271S100 calcium binding protein A1
img GENERIF, Score=793, Pubmed Id: 15780567, UMLKSK CUI: C1510502
img GENERIF, Score=1000, Pubmed Id: 17483815, UMLKSK CUI: C1510502
HumanPXN5829paxillin
img GENERIF, Score=966, Pubmed Id: 11759057, UMLKSK CUI: C1510502
HumanPRSS85652protease, serine, 8
img GENERIF, Score=861, Pubmed Id: 17145811, UMLKSK CUI: C1510502
HumanPAX25076paired box 2
img GENERIF, Score=1000, Pubmed Id: 18941400, UMLKSK CUI: C1510502
HumanMST1R4486macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
img GENERIF, Score=966, Pubmed Id: 12766581, UMLKSK CUI: C1510502
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
img GENERIF, Score=966, Pubmed Id: 18408592, UMLKSK CUI: C1510502
HumanMIF4282macrophage migration inhibitory factor (glycosylation-inhibiting factor)
img NCI, Score=801, Pubmed Id: 9140312, UMLKSK CUI: C1510502
HumanKITLG4254KIT ligand
img GENERIF, Score=1000, Pubmed Id: 16015044, UMLKSK CUI: C1510502
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img GENERIF, Score=793, Pubmed Id: 15780567, UMLKSK CUI: C1510502
img GENERIF, Score=966, Pubmed Id: 15791570, UMLKSK CUI: C1510502
HumanDRD21813dopamine receptor D2
img NCI, Score=801, Pubmed Id: 11444429, UMLKSK CUI: C1510502
HumanCLDN71366claudin 7
img GENERIF, Score=1000, Pubmed Id: 18799195, UMLKSK CUI: C1510502
img GENERIF, Score=827, Pubmed Id: 17922590, UMLKSK CUI: C1510502
HumanTNFSF8944tumor necrosis factor (ligand) superfamily, member 8
img NCI, Score=801, Pubmed Id: 12553555, UMLKSK CUI: C1510502
img NCI, Score=801, Pubmed Id: 12553555, UMLKSK CUI: C1510502
img NCI, Score=801, Pubmed Id: 12553555, UMLKSK CUI: C1510502
HumanCAV1857caveolin 1, caveolae protein, 22kDa
img GENERIF, Score=1000, Pubmed Id: 12810205, UMLKSK CUI: C1510502
HumanBRAF673v-raf murine sarcoma viral oncogene homolog B
img NCI, Score=801, Pubmed Id: 14602780, UMLKSK CUI: C1510502
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1510502Adenoma, Oxyphilic0self