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Genes (36)
Species:
human : 36 | |
| Human | IL1RL1 | 9173 | interleukin 1 receptor-like 1 | Soluble ST2, a marker for Th2 cytokine producing cells, is increased in sepsis and trauma patients | | Human | SGPL1 | 8879 | sphingosine-1-phosphate lyase 1 | extracellular S1P is dephosphorylated and subsequently converted by cells, which appears to be important for clearance of the signaling molecule S1P in the local tissue environment after infections or injuries | | Human | TNFSF11 | 8600 | tumor necrosis factor (ligand) superfamily, member 11 | We have discovered common sequence variants that are consistently associated with bone mineral density and with low-trauma fractures in three populations of European descent | | Human | VEGFA | 7422 | vascular endothelial growth factor A | results suggest that vascular endothelial growth factor (VEGF) is closely related to organ dysfunction in severe acute pancreatitis, and that VEGF may function as a protective factor via the anti-apoptotic effect against the organ injuries in this disease | | Human | UCP3 | 7352 | uncoupling protein 3 (mitochondrial, proton carrier) | IGF-1 may protect from hyperglycemia-induced oxidative stress and neuronal injuries by regulating mitochondrial membrane potential, possibly by the involvement of UCP3 | | Human | TNF | 7124 | tumor necrosis factor | Title:GENETIC PREDISPOSITION FOR A COMPROMISED IMMUNE SYSTEM AFTER MULTIPLE TRAUMA|Association:Not Found|Conclusion:Not Found Data demonstrate that non-lethal mechanical trauma causes significant TNFalpha production that in turn stimulates myocardial apoptosis via oxidative/nitrative stress Title:|Association:Not Found|Conclusion:The A-allele at the -308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis and possibly for death after trauma. TNF-alpha mRNA in trauma patients was not increased on admission (1.7 +/- 0.9) and decreased even below baseline after 12 h An altered pattern of TNF-alpha release was observed in trauma patients treated with catecholamines Pro-inflammatory cytokines derived from surgical trauma may enhance tumor cell adhesion to microvascular endothelial cells and thus bring about more successful tumor cell implantation resulting in an increased risk of metastasis formation | | Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | higher activity genotypes (L(A)/L(A), L(A)/S, L(A)/L(G)), rather than the low activity genotypes (S/S, S/L(G), L(G)/L(G)), are associated with an increased incidence of major depressive disease in the presence of environmental trauma | | Human | SELE | 6401 | selectin E | minor trauma to skin may induce expression of E-selectin, ICAM-1 and IL-8 | | Human | S100B | 6285 | S100 calcium binding protein B | S 100 B may be a reliable marker of brain damage in TBI without multiple trauma 24 h after trauma and thereafter | | Human | POMC | 5443 | proopiomelanocortin | An altered pattern of beta-endorphin release was observed in trauma patients treated with catecholamines | | Human | NTSR1 | 4923 | neurotensin receptor 1 (high affinity) | NT and NTR1 are part of network activated after mucosal injuries, and NT stimulates epithelial restitution, at least in part, through a COX-2 dependent pathway | | Human | NPY | 4852 | neuropeptide Y | In this review, NPY is a mediator and a marker of chronic stress in humans, including extreme trauma and posttraumatic stress disorder | | Human | NFKB1 | 4790 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | intranuclear presence of NF-kappaB in monocytes from patients with multiple injuries significantly increased on admission (88 +/- 37) and 6 h after trauma (59 +/- 28) compared with the baseline level | | Human | MAOA | 4128 | monoamine oxidase A | MAOA seems to moderate the impact of childhood trauma on adult psychopathology in female subjects in the same way as previously shown among male subjects | | Human | LBP | 3929 | lipopolysaccharide binding protein | Single nucleotide polymorphism of the LBP gene is not assciated with complicated sepsis after trauma | | Human | IL18 | 3606 | interleukin 18 (interferon-gamma-inducing factor) | Major trauma can lead to a marked elevation of interleukin-18, which might be associated with organ dysfunction In primary Sjogren's syndrome, infiltration of the salivary gland by macrophages and dendritic cells and expression of IL-18 and IL-12 play active roles in infiltrative injuries and have a correlation with predictors of lymphoma development | | Human | IL11 | 3589 | interleukin 11 | in contrast to IL-6, IL-11 in plasma does not correlate with trauma severity | | Human | IL10 | 3586 | interleukin 10 | An altered pattern of IL-10 release was observed in trauma patients treated with catecholamines IL-10 -1082 genotype may be a risk marker for development of acute respiratory failure after trauma | | Human | IL8 | 3576 | interleukin 8 | Title:|Association:Not Found|Conclusion:Not Found minor trauma to skin may induce expression of E-selectin, ICAM-1 and IL-8 | | Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | Title:|Association:Not Found|Conclusion:Not Found An altered pattern of IL-6 release was observed in trauma patients treated with catecholamines The -572 polymorphism, a unique variation in the IL-6 promoter in the Chinese Han population, may be used as a relevant risk estimate for sepsis in trauma patients | | Human | IL1A | 3552 | interleukin 1, alpha | Title:|Association:Not Found|Conclusion:Not Found | | Human | ICAM1 | 3383 | intercellular adhesion molecule 1 | minor trauma to skin may induce expression of E-selectin, ICAM-1 and IL-8 | | Human | GPT | 2875 | glutamic-pyruvate transaminase (alanine aminotransferase) | Provides a quantitative analysis of the main impact of the trauma of liver resection, liver ischemia, and other factors on the postoperative evolution of transaminases | | Human | GH1 | 2688 | growth hormone 1 | Growth hormone improves small bowel homeostasis after severe trauma independent from small bowel epithelial cell apoptosis or proliferation, probably by increasing the life span | | Human | F9 | 2158 | coagulation factor IX | Persistent bleeding after trauma |
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