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Details
Link-It Detail - Disease - C-cell hyperplasia
Debug Stats
  • ### Total Build Time: 13 ms 11.361 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 685 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 9.040 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
C-cell hyperplasia C1392158
Definition (1)
Neoplastic or reactive proliferation of the C-cells in the thyroid gland. The neoplastic C-cell hyperplasia is associated with familial medullary thyroid gland carcinoma and multiple endocrine neoplasia type II and IIB. Morphologically, it is characterized by the presence of clusters of intrafollicular C-cells with atypical cytologic features. The reactive C-cell hyperplasia is also known as physiological or secondary C-cell hyperplasia and it is associated with conditions that cause hypercalcemia (e.g., hyperparathyroidism).
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanSDHD6392succinate dehydrogenase complex, subunit D, integral membrane protein
img GAD, Score=833, Pubmed Id: 14557476, UMLKSK CUI: C1392158
HumanRLN26019relaxin 2
img GENERIF, Score=1000, Pubmed Id: 15956746, UMLKSK CUI: C1392158
HumanRLN16013relaxin 1
img GENERIF, Score=1000, Pubmed Id: 15956746, UMLKSK CUI: C1392158
HumanRET5979ret proto-oncogene
img GENERIF, Score=923, Pubmed Id: 12085189, UMLKSK CUI: C1392158
img GAD, Score=1000, Pubmed Id: 12085189, UMLKSK CUI: C1392158
img OMIM, Score=1000, UMLKSK CUI: C1392158
img GENERIF, Score=1000, Pubmed Id: 17384213, UMLKSK CUI: C1392158
HumanINSL33640insulin-like 3 (Leydig cell)
img GENERIF, Score=1000, Pubmed Id: 15956746, UMLKSK CUI: C1392158
HumanESR22100estrogen receptor 2 (ER beta)
img GENERIF, Score=1000, Pubmed Id: 17333268, UMLKSK CUI: C1392158
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1392158C-cell hyperplasia0self