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Details
Link-It Detail - Disease - Cardiac Hypertrophy
Debug Stats
  • ### Total Build Time: 52 ms 33.748 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 427 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=39 ms Completed: 39 ms rowSize= 31.676 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cardiac Hypertrophy C1383860
Definition (1)
Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
Genes (41)

Species:
human : 41
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMYOCD93649myocardin
img GENERIF, Score=1000, Pubmed Id: 18028454, UMLKSK CUI: C1383860
HumanTFB2M64216transcription factor B2, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 19096125, UMLKSK CUI: C1383860
HumanMYOZ251778myozenin 2
img GENERIF, Score=1000, Pubmed Id: 17347475, UMLKSK CUI: C1383860
HumanPRKAG251422protein kinase, AMP-activated, gamma 2 non-catalytic subunit
img GENERIF, Score=1000, Pubmed Id: 15766830, UMLKSK CUI: C1383860
HumanTFB1M51106transcription factor B1, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 19096125, UMLKSK CUI: C1383860
HumanIFT8128981intraflagellar transport 81 homolog (Chlamydomonas)
img GENERIF, Score=1000, Pubmed Id: 12549821, UMLKSK CUI: C1383860
HumanLATS226524large tumor suppressor kinase 2
img GENERIF, Score=1000, Pubmed Id: 18927464, UMLKSK CUI: C1383860
HumanYWHAQ10971tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
img GENERIF, Score=1000, Pubmed Id: 15930726, UMLKSK CUI: C1383860
HumanCORIN10699corin, serine peptidase
img GENERIF, Score=1000, Pubmed Id: 18669922, UMLKSK CUI: C1383860
img GENERIF, Score=673, Pubmed Id: 17296875, UMLKSK CUI: C1383860
HumanHCN410021hyperpolarization activated cyclic nucleotide-gated potassium channel 4
img GENERIF, Score=983, Pubmed Id: 18458081, UMLKSK CUI: C1383860
HumanAKT310000v-akt murine thymoma viral oncogene homolog 3
img GENERIF, Score=901, Pubmed Id: 15698844, UMLKSK CUI: C1383860
HumanHDAC49759histone deacetylase 4
img GENERIF, Score=1000, Pubmed Id: 17179159, UMLKSK CUI: C1383860
HumanVCL7414vinculin
img GENERIF, Score=1000, Pubmed Id: 16949038, UMLKSK CUI: C1383860
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 18464525, UMLKSK CUI: C1383860
HumanTNNT27139troponin T type 2 (cardiac)
img GENERIF, Score=734, Pubmed Id: 17101185, UMLKSK CUI: C1383860
HumanTNNI37137troponin I type 3 (cardiac)
img GENERIF, Score=861, Pubmed Id: 18175163, UMLKSK CUI: C1383860
img GENERIF, Score=734, Pubmed Id: 17101185, UMLKSK CUI: C1383860
HumanTHRB7068thyroid hormone receptor, beta
img GENERIF, Score=1000, Pubmed Id: 14684607, UMLKSK CUI: C1383860
HumanTFAM7019transcription factor A, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 19096125, UMLKSK CUI: C1383860
HumanSTK116794serine/threonine kinase 11
img GENERIF, Score=901, Pubmed Id: 17098823, UMLKSK CUI: C1383860
HumanSLC9A16548solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
img GENERIF, Score=1000, Pubmed Id: 18776042, UMLKSK CUI: C1383860
img GENERIF, Score=734, Pubmed Id: 18508719, UMLKSK CUI: C1383860
HumanRRAD6236Ras-related associated with diabetes
img GENERIF, Score=1000, Pubmed Id: 18056528, UMLKSK CUI: C1383860
HumanREN5972renin
img GENERIF, Score=861, Pubmed Id: 16940215, UMLKSK CUI: C1383860
HumanMAPK35595mitogen-activated protein kinase 3
img GENERIF, Score=1000, Pubmed Id: 19060905, UMLKSK CUI: C1383860
HumanPPP3CB5532protein phosphatase 3, catalytic subunit, beta isozyme
img GENERIF, Score=901, Pubmed Id: 15557343, UMLKSK CUI: C1383860
HumanPPARA5465peroxisome proliferator-activated receptor alpha
img GENERIF, Score=1000, Pubmed Id: 12655356, UMLKSK CUI: C1383860
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1383860Cardiac Hypertrophy0self