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Details
Link-It Detail - Disease - Liposarcoma - differentiated
Debug Stats
  • ### Total Build Time: 117 ms 29.521 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 354 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 567 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=86 ms Completed: 86 ms rowSize= 15.131 KB
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 12.258 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Liposarcoma - differentiated C1370889
Definition (1)
A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation.
Relationships (30)

Relation Types:
diso_​to_​anat : 16
diso_​to_​diso : 14


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​finding_​of_​disease : 5
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​not_​normal_​tissue_​origin_​of_​disease : 1
isa : 3
may_​be_​abnormal_​cell_​of_​disease : 2
may_​be_​cytogenetic_​abnormality_​of_​disease : 4
may_​be_​finding_​of_​disease : 2
may_​be_​molecular_​abnormality_​of_​disease : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Adipocyte C0206131
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Adipose Tissue C0001527
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell of connective tissue C0009781
DISO_to_ANATis_associated_anatomic_site_ofimg Connective and Soft Tissue C1516798
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_not_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Lipocyte C1708888
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Monovacuolated Lipoblast C1513487
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Multivacuolated Lipoblast C1513755
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Connective and Soft Tissue Cell C1513942
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lipocyte C1709184
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Mature Adipocyte C1709185
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Nerve Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System C1518293
DISO_to_ANATmay_be_cytogenetic_abnormality_of_diseaseimg Ring Chromosomes C0035639
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 12q C1517384
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 1q C1517401
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Giant Rod Chromosome C1517546
DISO_to_DISOis_not_finding_of_diseaseimg High Grade Lesion C1334016
DISO_to_DISOis_not_finding_of_diseaseimg Indolent Clinical Course C1334168
DISO_to_DISOisaimg Inflammatory liposarcoma C1370890
DISO_to_DISOis_not_finding_of_diseaseimg Intermediate Filaments Present C1708535
DISO_to_DISOis_not_finding_of_diseaseimg Intracytoplasmic Eosinophilic Inclusion C1711292
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg MDM2 Gene Amplification C1518116
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanPPIAL4A164022peptidylprolyl isomerase A (cyclophilin A)-like 4A
img NCI, Score=801, Pubmed Id: 11948409, UMLKSK CUI: C1370889
HumanHMGA28091high mobility group AT-hook 2
img NCI, Score=801, Pubmed Id: 14612541, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 10727978, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 9212729, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 11391797, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 16821597, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 14612541, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 12792777, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 17001166, UMLKSK CUI: C1370889
img NCI, Score=801, Pubmed Id: 9205100, UMLKSK CUI: C1370889
HumanSTC16781stanniocalcin 1
img GENERIF, Score=850, Pubmed Id: 15149855, UMLKSK CUI: C1370889
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=1000, Pubmed Id: 18779733, UMLKSK CUI: C1370889
HumanCAV1857caveolin 1, caveolae protein, 22kDa
img NCI, Score=801, Pubmed Id: 11238032, UMLKSK CUI: C1370889
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1370889Liposarcoma - differentiated0self