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Details
Link-It Detail - Disease - Adult granulosa cell tumor of the ovary
Debug Stats
  • ### Total Build Time: 8 ms 7.222 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 376 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 888 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 4.641 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adult granulosa cell tumor of the ovary C1370419
Definition (1)
A granulosa-stromal cell tumor that arises from the ovary. It is characterized by the presence of granulosa cells that comprise at least ten percent of the cellular population. The granulosa cells are often found in a background that contains theca and fibrous cells. There are two major subtypes recognized, adult and juvenile granulosa cell tumor. Clinically, patients may present with an abdominal mass. Symptoms depend on the patient's age. The most important indicator of prognosis is tumor stage. Age over forty years at the time of the initial diagnosis, large tumor size, bilaterality, cellular atypia, and increased mitotic activity are factors indicating a potentially aggressive clinical course and relative poor prognosis.
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanSTK116794serine/threonine kinase 11
img NCI, Score=801, Pubmed Id: 10389980, UMLKSK CUI: C1370419
HumanPTH1R5745parathyroid hormone 1 receptor
img OMIM, Score=900, UMLKSK CUI: C1370419
HumanCDH1999cadherin 1, type 1, E-cadherin (epithelial)
img NCI, Score=801, Pubmed Id: 14970867, UMLKSK CUI: C1370419
HumanAMH268anti-Mullerian hormone
img NCI, Score=801, Pubmed Id: 10690852, UMLKSK CUI: C1370419
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1370419Adult granulosa cell tumor of the ovary0self