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Details
Link-It Detail - Disease - Pancreatic Ductal Adenocarcinoma
Debug Stats
  • ### Total Build Time: 57 ms 60.474 KB
  • CONCEPT_NAME gt=20 ms Completed: 20 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 642 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=13 ms Completed: 13 ms rowSize= 15.439 KB
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 42.817 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Pancreatic Ductal Adenocarcinoma C1335302
Definition (1)
An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor.
Relationships (60)

Relation Types:
diso_​to_​anat : 20
diso_​to_​diso : 40


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 6
is_​not_​finding_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 3
isa : 9
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 11
may_​be_​finding_​of_​disease : 4
may_​be_​molecular_​abnormality_​of_​disease : 9
Page Size
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  Page 1 of 3
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Acinar Carcinoma Cell C1882991
DISO_to_ANATis_abnormal_cell_of_diseaseimg Adenocarcinoma Cell C1510779
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Digestive System C0012240
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Exocrine pancreas C0553695
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Glandular Cell C1517548
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Glandular Epithelium C0682578
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Neuroendocrine Cell C1518216
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_associated_anatomic_site_ofimg Pancreas C0030274
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Pancreatic Ducts C0030288
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg AKT2 Gene Amplification C1515843
DISO_to_DISOmay_be_finding_of_diseaseimg Abdominal Pain C0000737
DISO_to_DISOis_not_finding_of_diseaseimg Acinar Cell Differentiation C1879542
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg BRCA2 Gene Inactivation C1511025
DISO_to_DISOis_not_finding_of_diseaseimg Benign Cellular Infiltrate C1332480
Genes (93)

Species:
human : 92
mouse : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseEPHA21969EPH receptor A2
img NCI, Score=801, Pubmed Id: 14871820, UMLKSK CUI: C1335302
HumanREG483998regenerating islet-derived family, member 4
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C1335302
HumanPRSS2783886protease, serine 27
img NCI, Score=801, Pubmed Id: 12441343, UMLKSK CUI: C1335302
HumanS100PBP64766S100P binding protein
img GENERIF, Score=1000, Pubmed Id: 15632002, UMLKSK CUI: C1335302
img GENERIF, Score=1000, Pubmed Id: 18089492, UMLKSK CUI: C1335302
HumanMUC3B57876mucin 3B, cell surface associated
img NCI, Score=801, Pubmed Id: 12657964, UMLKSK CUI: C1335302
HumanWHSC1L154904Wolf-Hirschhorn syndrome candidate 1-like 1
img NCI, Score=801, Pubmed Id: 15983384, UMLKSK CUI: C1335302
HumanFXYD553827FXYD domain containing ion transport regulator 5
img NCI, Score=801, Pubmed Id: 12586803, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12586803, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12586803, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12586803, UMLKSK CUI: C1335302
HumanCADM123705cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 12432281, UMLKSK CUI: C1335302
HumanCLCA422802chloride channel accessory 4
img NCI, Score=801, Pubmed Id: 12711595, UMLKSK CUI: C1335302
HumanPARK711315parkinson protein 7
img GENERIF, Score=1000, Pubmed Id: 18706098, UMLKSK CUI: C1335302
HumanPSIP111168PC4 and SFRS1 interacting protein 1
img NCI, Score=801, Pubmed Id: 14613990, UMLKSK CUI: C1335302
HumanCOPS510987COP9 signalosome subunit 5
img NCI, Score=801, Pubmed Id: 14719054, UMLKSK CUI: C1335302
HumanNDRG110397N-myc downstream regulated 1
img GENERIF, Score=1000, Pubmed Id: 16778198, UMLKSK CUI: C1335302
HumanMSLN10232mesothelin
img NCI, Score=801, Pubmed Id: 15696124, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 14576474, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 11751476, UMLKSK CUI: C1335302
HumanCLCA29635chloride channel accessory 2
img NCI, Score=801, Pubmed Id: 12711595, UMLKSK CUI: C1335302
HumanGDF159518growth differentiation factor 15
img NCI, Score=801, Pubmed Id: 15073115, UMLKSK CUI: C1335302
HumanTJP29414tight junction protein 2
img NCI, Score=801, Pubmed Id: 10495427, UMLKSK CUI: C1335302
HumanEBAG99166estrogen receptor binding site associated, antigen, 9
img NCI, Score=801, Pubmed Id: 12499917, UMLKSK CUI: C1335302
img GENERIF, Score=1000, Pubmed Id: 11992411, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12499917, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12499917, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12499917, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 11992411, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 12499917, UMLKSK CUI: C1335302
HumanCLDN19076claudin 1
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 15693851, UMLKSK CUI: C1335302
HumanSKAP28935src kinase associated phosphoprotein 2
img GENERIF, Score=1000, Pubmed Id: 17952125, UMLKSK CUI: C1335302
HumanNRP28828neuropilin 2
img GENERIF, Score=756, Pubmed Id: 19088020, UMLKSK CUI: C1335302
HumanADAM98754ADAM metallopeptidase domain 9
img NCI, Score=801, Pubmed Id: 14997207, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 14997207, UMLKSK CUI: C1335302
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=694, Pubmed Id: 16751802, UMLKSK CUI: C1335302
HumanTFPI27980tissue factor pathway inhibitor 2
img NCI, Score=801, Pubmed Id: 15592528, UMLKSK CUI: C1335302
img NCI, Score=801, Pubmed Id: 15592528, UMLKSK CUI: C1335302
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
img GENERIF, Score=884, Pubmed Id: 18162774, UMLKSK CUI: C1335302
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1335302Pancreatic Ductal Adenocarcinoma0self