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Details
Link-It Detail - Disease - Gastric MALT Lymphoma
Debug Stats
  • ### Total Build Time: 42 ms 51.845 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 340 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 566 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=28 ms Completed: 28 ms rowSize= 15.807 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 33.928 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gastric MALT Lymphoma C1333782
Definition (1)
A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.
Relationships (39)

Relation Types:
diso_​to_​anat : 29
diso_​to_​diso : 10


Relationships:
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 6
is_​normal_​tissue_​origin_​of_​disease : 5
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 3
isa : 1
may_​be_​abnormal_​cell_​of_​disease : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 3
may_​be_​finding_​of_​disease : 1
may_​be_​molecular_​abnormality_​of_​disease : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg B lymphoblast C1516097
DISO_to_ANATis_normal_cell_origin_of_diseaseimg B-Lymphocytes C0004561
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Cells, Reed-Sternberg C0085133
DISO_to_ANATis_abnormal_cell_of_diseaseimg Centrocyte-Like Cell C1516393
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Gut associated lymphoid tissue C0596638
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphatic Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Marginal Zone C1711368
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Marginal Zone B-Lymphocyte C1512992
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature B-Cell C1513019
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Myeloid Cells C0887899
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic B-Lymphocyte C1513929
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lymphocyte C1514011
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Neoplastic Monocytoid B-Lymphocyte C1514028
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Neoplastic Plasma Cell C1514058
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell C1514110
Genes (16)

Species:
human : 16
SpeciesGeneGeneIdGene NameEvidence
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
img NCI, Score=801, Pubmed Id: 14760068, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 12406890, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15694184, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 11197361, UMLKSK CUI: C1333782
HumanBCL108915B-cell CLL/lymphoma 10
img NCI, Score=801, Pubmed Id: 11830492, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15845895, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 11830492, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 17167822, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 11830492, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15845895, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 16344587, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15845895, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15337797, UMLKSK CUI: C1333782
HumanMADCAM18174mucosal vascular addressin cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 11504840, UMLKSK CUI: C1333782
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 15146559, UMLKSK CUI: C1333782
HumanTLR47099toll-like receptor 4
img GENERIF, Score=1000, Pubmed Id: 16019531, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 16019531, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 16019531, UMLKSK CUI: C1333782
HumanSPN6693sialophorin
img NCI, Score=801, Pubmed Id: 10469212, UMLKSK CUI: C1333782
HumanST6GAL16480ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
img NCI, Score=801, Pubmed Id: 10469212, UMLKSK CUI: C1333782
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 15222024, UMLKSK CUI: C1333782
HumanMICB4277MHC class I polypeptide-related sequence B
img GENERIF, Score=756, Pubmed Id: 15304008, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15304008, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15304008, UMLKSK CUI: C1333782
HumanHLA-DQB13119
img GENERIF, Score=827, Pubmed Id: 16234023, UMLKSK CUI: C1333782
HumanCXCR32833chemokine (C-X-C motif) receptor 3
img GENERIF, Score=1000, Pubmed Id: 18616679, UMLKSK CUI: C1333782
HumanCTLA41493cytotoxic T-lymphocyte-associated protein 4
img GENERIF, Score=1000, Pubmed Id: 16849765, UMLKSK CUI: C1333782
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=988, Pubmed Id: 16357845, UMLKSK CUI: C1333782
HumanCDKN1C1028cyclin-dependent kinase inhibitor 1C (p57, Kip2)
img GENERIF, Score=988, Pubmed Id: 16357845, UMLKSK CUI: C1333782
HumanMS4A1931membrane-spanning 4-domains, subfamily A, member 1
img NCI, Score=801, Pubmed Id: 10496597, UMLKSK CUI: C1333782
img NCI, Score=801, Pubmed Id: 15841725, UMLKSK CUI: C1333782
HumanCXCR5643chemokine (C-X-C motif) receptor 5
img NCI, Score=801, Pubmed Id: 10562310, UMLKSK CUI: C1333782
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1333782Gastric MALT Lymphoma0self