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Details
Link-It Detail - Disease - Autoimmune Lymphoproliferative Syndrome
Debug Stats
  • ### Total Build Time: 43 ms 28.300 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 376 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 383 bytes
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  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 3.979 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Autoimmune Lymphoproliferative Syndrome C1328840
Definition (1)
An autoimmune hematologic disorder characterized by autoimmune hemolytic anemia, thrombocytopenia, lymphadenopathy, hepatomegaly and splenomegaly. Patients are at an increased risk of developing Hodgkin and non-Hodgkin lymphomas.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Lymphoproliferative Disorders C0024314
img Genetic Diseases, Inborn C0950123
img Autoimmune Diseases C0004364
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210704img Lymphoproliferative Disorders C0024314
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242284img Lymphoproliferative Disorders C0024314
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Genetic Diseases, Inborn C09501233img Genetic Diseases, Inborn C0950123
img Immune System Diseases C0021053img Autoimmune Diseases C00043643img Autoimmune Diseases C0004364
Relationships (55)

Relation Types:
diso_​to_​anat : 3
diso_​to_​chem : 1
diso_​to_​diso : 41
diso_​to_​phen : 8
diso_​to_​phys : 2


Relationships:
none : 4
disease_​has_​associated_​disease : 1
is_​abnormal_​cell_​of_​disease : 1
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 1
isa : 4
manifestation_​of : 25
mapped_​to : 1
may_​be_​associated_​disease_​of_​disease : 5
may_​be_​finding_​of_​disease : 6
permuted_​term_​of : 1
related_​to : 3
used_​for : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN26img genetic aspects C0017399
DISO_to_CHEM11img Antigens, CD95 C0245662
DISO_to_DISO11img Complication Aspects C1171258
DISO_to_PHYS8img Mutation C0026882
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_associated_anatomic_site_ofimg Immune System C0020962
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_DISOpermuted_term_ofimg ALPS C1328840
DISO_to_DISOdisease_has_associated_diseaseimg ALPS-Associated Lymphoma C1510972
DISO_to_DISOrelated_toimg ALPS1A C1866119
DISO_to_DISOrelated_toimg ALPS1B C1866120
DISO_to_DISOmay_be_associated_disease_of_diseaseimg AUTOIMMUNE DIS C0004364
DISO_to_DISOrelated_toimg AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE I, AUTOSOMAL RECESSIVE C1866121
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Anemia C0002871
DISO_to_DISOused_forimg Anemia, Hemolytic, Autoimmune C0002880
DISO_to_DISOmanifestation_ofimg Anemia, Iron-Deficiency C0162316
DISO_to_DISOmanifestation_ofimg Auto-immune thrombocytopenia C0242584
DISO_to_DISOmapped_toimg Autoimmune lymphoproliferative syndrome without FAS mutations C2931071
DISO_to_DISOmanifestation_ofimg Autoimmune neutropenia C0340971
DISO_to_DISOmanifestation_ofimg Caused by mutations in the Fas antigen gene (FAS, 134637.0001) C1866124
DISO_to_DISOmanifestation_ofimg Caused by mutations in the Fas ligand gene (FASL, 134638.0001) C1866125
DISO_to_DISOmanifestation_ofimg Chronic noninfectious lymphadenopathy C1858970
DISO_to_DISOmanifestation_ofimg Defective lymphocyte apoptosis C1858969
DISO_to_DISOmanifestation_ofimg Elevated levels of vitamin B12 C1866123
DISO_to_DISOmay_be_finding_of_diseaseimg Enlarged Liver C0019209
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanCASP10843caspase 10, apoptosis-related cysteine peptidase
img GENERIF, Score=1000, Pubmed Id: 16446975, UMLKSK CUI: C1328840
HumanFAS355Fas cell surface death receptor
img GENERIF, Score=1000, Pubmed Id: 12139945, UMLKSK CUI: C1328840
img GENERIF, Score=1000, Pubmed Id: 11830507, UMLKSK CUI: C1328840
img GENERIF, Score=1000, Pubmed Id: 15557123, UMLKSK CUI: C1328840
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1328840Autoimmune Lymphoproliferative Syndrome0self