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Details
Link-It Detail - Disease - ACTH-Secreting Pituitary Adenoma
Debug Stats
  • ### Total Build Time: 90 ms 42.259 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 237 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_TEXT gt=NONE 1 ms Completed: 1 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 980 bytes
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 553 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 10.422 KB
  • CONCEPT_RELATIONSHIPS gt=25 ms Completed: 25 ms rowSize= 15.190 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 13.188 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
ACTH-Secreting Pituitary Adenoma C1306214
Definition (1)
A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Pituitary Neoplasms C0032019
img Adenoma C0001430
Children (1)
img Nelson Syndrome C0027577
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Site C00276535img Pituitary Neoplasms C0032019
img Endocrine System Diseases C0014130img Endocrine Gland Neoplasms C00141324img Pituitary Neoplasms C0032019
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076828img Pituitary Neoplasms C0032019
img Neoplasms C0027651img Neoplasms by Site C00276539img Pituitary Neoplasms C0032019
img Nervous System Diseases C0027765img Nervous System Neoplasms C00277668img Pituitary Neoplasms C0032019
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076827img Pituitary Neoplasms C0032019
img Endocrine System Diseases C0014130img Pituitary Diseases C00320024img Pituitary Neoplasms C0032019
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Adenoma C0001430
Relationships (39)

Relation Types:
diso_​to_​anat : 23
diso_​to_​chem : 2
diso_​to_​diso : 13
diso_​to_​phen : 1


Relationships:
none : 10
alias_​of : 1
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 9
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
may_​be_​molecular_​abnormality_​of_​disease : 2
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO90img Adenoma C0001430
DISO_to_DISO44img Pituitary ACTH Hypersecretion C0221406
DISO_to_DISO39img Pituitary Neoplasms C0032019
DISO_to_DISO27img Complication Aspects C1171258
DISO_to_PHEN21img genetic aspects C0017399
DISO_to_DISO16img Cushing Syndrome C0010481
DISO_to_CHEM10img Adrenocorticotropic Hormone C0001655
DISO_to_DISO10img Adenoma C0001430
DISO_to_DISO9img CANINE DIS C0012979
DISO_to_ANAT8img In Blood C0005768
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Adenohypophysial Cell C1706715
DISO_to_ANATis_associated_anatomic_site_ofimg Base of skull structure C0149543
DISO_to_ANATis_associated_anatomic_site_ofimg Bone structure of cranium C0037303
DISO_to_ANATis_associated_anatomic_site_ofimg Brain C0006104
DISO_to_ANATis_associated_anatomic_site_ofimg Central Nervous System C0927232
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Corticotroph C1707524
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Endocrine System C0014136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Glandular Epithelial Tissue C1708242
DISO_to_ANATis_associated_anatomic_site_ofimg Head and neck structure C0460004
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Adenohypophysial Cell C1708860
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Adenohypophysial Cell C1709161
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Endocrine Cell C1513951
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanHGS9146hepatocyte growth factor-regulated tyrosine kinase substrate
img GENERIF, Score=988, Pubmed Id: 16832584, UMLKSK CUI: C1306214
HumanPOMC5443proopiomelanocortin
img GENERIF, Score=901, Pubmed Id: 18057378, UMLKSK CUI: C1306214
HumanPITX15307paired-like homeodomain 1
img NCI, Score=801, Pubmed Id: 10902805, UMLKSK CUI: C1306214
img NCI, Score=801, Pubmed Id: 10902805, UMLKSK CUI: C1306214
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
img GENERIF, Score=901, Pubmed Id: 17917309, UMLKSK CUI: C1306214
HumanPCNA5111proliferating cell nuclear antigen
img GENERIF, Score=966, Pubmed Id: 16201313, UMLKSK CUI: C1306214
HumanMIF4282macrophage migration inhibitory factor (glycosylation-inhibiting factor)
img NCI, Score=801, Pubmed Id: 9140312, UMLKSK CUI: C1306214
HumanIL1RN3557interleukin 1 receptor antagonist
img NCI, Score=801, Pubmed Id: 9639249, UMLKSK CUI: C1306214
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
INFERRED, Score=800, UMLKSK CUI: C1306214
HumanGHRH2691growth hormone releasing hormone
img NCI, Score=801, Pubmed Id: 1350590, UMLKSK CUI: C1306214
HumanCRHR11394corticotropin releasing hormone receptor 1
img NCI, Score=801, Pubmed Id: 9100600, UMLKSK CUI: C1306214
HumanNR0B1190nuclear receptor subfamily 0, group B, member 1
img NCI, Score=801, Pubmed Id: 16061826, UMLKSK CUI: C1306214
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1306214ACTH-Secreting Pituitary Adenoma0self