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Details
Link-It Detail - Disease - CHRONIC LEUKEMIA
Debug Stats
  • ### Total Build Time: 49 ms 39.860 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 594 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=8 ms Completed: 8 ms rowSize= 13.972 KB
  • CONCEPT_GENES gt=27 ms Completed: 27 ms rowSize= 23.766 KB
  • CONCEPT_XREFS gt=11 ms Completed: 11 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
CHRONIC LEUKEMIA C1279296
Definition (1)
A slowly progressing leukemia characterized by a clonal (malignant) proliferation of maturing and mature myeloid cells or mature lymphocytes. When the clonal cellular population is composed of myeloid cells, the process is called chronic myelogenous leukemia. When the clonal cellular population is composed of lymphocytes, it is classified as chronic lymphocytic leukemia, hairy cell leukemia, or T-cell large granular lymphocyte leukemia.
Relationships (27)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 20


Relationships:
associated_​with : 2
is_​abnormal_​cell_​of_​disease : 3
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 14
mapped_​to : 1
replaces : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Bone Marrow C0005953
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_associated_anatomic_site_ofimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Cell C1517806
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_DISOis_not_finding_of_diseaseimg Acute Clinical Course C1332147
DISO_to_DISOisaimg Aggressive NK cell leukaemia C1292777
DISO_to_DISOisaimg CGL, chronic phase C0023474
DISO_to_DISOmapped_toimg CHRONIC LEUKEMIA C1279296
DISO_to_DISOisaimg CMML C0023480
DISO_to_DISOassociated_withimg Chr leuk uns cl w rmson C0686589
DISO_to_DISOisaimg Chronic Lymphocytic Leukemia C0023434
DISO_to_DISOisaimg Chronic Monocytic Leukemia C0023466
DISO_to_DISOisaimg Chronic Neutrophilic Leukemia C0023481
DISO_to_DISOisaimg Chronic eosinophilic leukemia C0346421
DISO_to_DISOassociated_withimg Chronic leukaemia, NOS, without mention of remission C0686588
DISO_to_DISOisaimg Chronic lymphoid leukaemia - category C1531666
DISO_to_DISOisaimg Chronic myeloid leukaemia - category C1531667
DISO_to_DISOisaimg HCL-V C0349633
DISO_to_DISOisaimg Hairy Cell Leukemia C0023443
DISO_to_DISOreplacesimg Leukemia C0023418
DISO_to_DISOisaimg Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
DISO_to_DISOisaimg Leukemia, Prolymphocytic C0023486
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanTCL1A8115T-cell leukemia/lymphoma 1A
img NCI, Score=801, Pubmed Id: 8415691, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 9892178, UMLKSK CUI: C1279296
HumanTNF7124tumor necrosis factor
img GENERIF, Score=913, Pubmed Id: 15986200, UMLKSK CUI: C1279296
HumanTFRC7037transferrin receptor (p90, CD71)
img NCI, Score=801, Pubmed Id: 2899182, UMLKSK CUI: C1279296
HumanTRG@6965
img NCI, Score=801, Pubmed Id: 3257920, UMLKSK CUI: C1279296
HumanSRC6714v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
img GENERIF, Score=694, Pubmed Id: 16959222, UMLKSK CUI: C1279296
HumanABCB45244ATP-binding cassette, sub-family B (MDR/TAP), member 4
img NCI, Score=801, Pubmed Id: 9150348, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 1972761, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 1972761, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 9150348, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 9150348, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 1972761, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 9150348, UMLKSK CUI: C1279296
img NCI, Score=801, Pubmed Id: 9150348, UMLKSK CUI: C1279296
HumanNPM14869nucleophosmin (nucleolar phosphoprotein B23, numatrin)
img NCI, Score=801, Pubmed Id: 12024032, UMLKSK CUI: C1279296
HumanMVK4598mevalonate kinase
img NCI, Score=801, Pubmed Id: 9714005, UMLKSK CUI: C1279296
HumanLOR4014loricrin
img NCI, Score=801, Pubmed Id: 2983419, UMLKSK CUI: C1279296
HumanJAK23717Janus kinase 2
img NCI, Score=801, Pubmed Id: 12024032, UMLKSK CUI: C1279296
img GENERIF, Score=694, Pubmed Id: 16959222, UMLKSK CUI: C1279296
HumanHOXA103206homeobox A10
img NCI, Score=801, Pubmed Id: 7556525, UMLKSK CUI: C1279296
HumanGATA12623GATA binding protein 1 (globin transcription factor 1)
img GENERIF, Score=840, Pubmed Id: 17408401, UMLKSK CUI: C1279296
HumanFLT32322fms-related tyrosine kinase 3
img GENERIF, Score=875, Pubmed Id: 17936561, UMLKSK CUI: C1279296
HumanCCND1595cyclin D1
img GENERIF, Score=694, Pubmed Id: 16959222, UMLKSK CUI: C1279296
HumanAPOE348apolipoprotein E
img GENERIF, Score=708, Pubmed Id: 18784741, UMLKSK CUI: C1279296
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1279296CHRONIC LEUKEMIA0self