Human | CCR2 | 729230 | chemokine (C-C motif) receptor 2 | evaluated the possible relation between CCR2 and CCR5 alleles and blood pressure (BP) levels in hypertensive |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | APM linkage analysis suggested that the DD2R gene TaqI polymorphism had evidence of linkage with blood pressure, as well as with obesity |
Human | WNK1 | 65125 | WNK lysine deficient protein kinase 1 | Title:|Association:Not Found|Conclusion:Not Found WNK1 variants on blood pressure are mediated via effects on the gradient of blood pressure change with age |
Human | SLC4A5 | 57835 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5 | These results additionally confirm the involvement of SLC4A5 with blood pressure control, although the mechanism is still unclear |
Human | RNLS | 55328 | renalase, FAD-dependent amine oxidase | Renalase regulates cardiac function and blood pressure |
Human | ERAP1 | 51752 | endoplasmic reticulum aminopeptidase 1 | Data show that adipocyte-derived leucine aminopeptidase (A-LAP) plays important roles in the regulation of blood pressure under both the physiological and pathological conditions |
Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | Several ghrelin gene variations were associated with blood pressure levels in subjects with impaired glucose tolerance Ghrelin, as well as AM, may play an important role as vasodilator local hormones and regulation of blood pressure during hemodialysis, especially the occurrence of episodic hypotension |
Human | STK39 | 27347 | serine threonine kinase 39 | variants in STK39 may influence blood pressure by increasing STK39 expression and consequently altering renal Na(+) excretion |
Human | NEDD4L | 23327 | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | genetic NEDD4L variation affecting cross-sectional and longitudinal blood pressure is possibly as a consequence of altered NEDD4L interaction with ENaC |
Human | NISCH | 11188 | nischarin | shows strong affinity to clonidine and regulates blood pressure |
Human | PPARGC1A | 10891 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | PPARGC1 can participate in blood pressure control, and sequence substitutions at its gene locus confer an increased risk of hypertension to a substantial proportion of men |
Human | ROCK2 | 9475 | Rho-associated, coiled-coil containing protein kinase 2 | Common variation in ROCK2 exerts systemic resistance-mediated changes in blood pressure and is novel mechanism for human circulatory control and suggests new possibilities for diagnosis and treatment of subjects at risk of hypertension |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | blood pressure is inversely related to the plasma adiponectin independent of the other variables of the metabolic syndrome and other risk factors of coronary artery disease in healthy adolescent females |
Human | KL | 9365 | klotho | KLOTHO G395A polymorphism was associated with blood pressure and KLOTHO C1818T polymorphism was associated with glucose metabolism |
Human | DGAT1 | 8694 | diacylglycerol O-acyltransferase 1 | Polymorphism associated with alterations in body mass index, high density lipoprotein levels and blood pressure in Turkish women |
Human | SLC14A2 | 8170 | solute carrier family 14 (urea transporter), member 2 | Title:Genetic variation in the human urea transporter-2 is associated with variation in blood pressure.|Association:Y|Conclusion:The Ile227 and Ala357 alleles were associated with low diastolic BP in men but not women, with odds ratios 2.1 [95% confidence interval (CI) 1.5-2.7, P < 0.001] and 1.5 (95% CI 1.2-1.8, P < 0.001), respectively. There was a similar trend for systolic BP, and odds ratios for the Ile227 and Ala357 alleles were 1.7 (95% CI 1.2-2.3, P = 0.002) and 1.3 (95% CI 1.1-1.6, P = 0.007), respectively, in men. |
Human | XDH | 7498 | xanthine dehydrogenase | These results suggest that polymorphisms -337GA and 565+64CT of XDH gene are related with blood pressure and oxidative stress in hypertension, adding evidence to the role of xanthine oxidoreductase and oxidative stress in blood pressure |
Human | VDR | 7421 | vitamin D (1,25- dihydroxyvitamin D3) receptor | Title:[Influence of the vitamin D receptor gene polymorphism and 25-hydroxyvitamin D on arterial pressure in health individuals]|Association:Not Found|Conclusion:Healthy men with higher levels of vitamin D have higher levels of SBP and DBP. Moreover, men with bb genotype have the highest levels of SBP. Blood pressure levels in women are not influenced by vitamin D nor by Bsml genotype. Our data suggest a possible pathophysiological interaction between vitamin D and sex hormones in blood pressure control. |
Human | UCP1 | 7350 | uncoupling protein 1 (mitochondrial, proton carrier) | UCP1 genetic polymorphisms are associated with blood pressure among Korean female subjects |
Human | TNFRSF1B | 7133 | tumor necrosis factor receptor superfamily, member 1B | insulin resistance and blood pressure are linked to altered shedding of TNF-alpha receptors in type 2 diabetes mellitus |
Human | TNFRSF1A | 7132 | tumor necrosis factor receptor superfamily, member 1A | insulin resistance and blood pressure are linked to altered shedding of TNF-alpha receptors in type 2 diabetes mellitus |
Human | TH | 7054 | tyrosine hydroxylase | Results suggest novel pathophysiological links between a key adrenergic locus, catecholamine metabolism via tyrosine hydroxylase, and blood pressure |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | Title:|Association:Y|Conclusion:Not Found |
Human | TAP1 | 6890 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | A/G polymorphisms at codon 637 of the TAP1 gene contributes to the risk of hypertension, possibly via the increases in blood pressure and body mass index |
Human | TAF1 | 6872 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | Title:|Association:Y|Conclusion:Not Found |