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Details
Link-It Detail - Disease - Central Osteosarcoma
Debug Stats
  • ### Total Build Time: 12 ms 19.141 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 338 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 604 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 15.458 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 1.538 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.154 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Central Osteosarcoma C1266166
Definition (1)
A high grade malignant bone-forming mesenchymal neoplasm producing osteoid. The tumor arises from the medullary portion of the bone. It affects the long bones and most commonly, the distal femur, proximal tibia, and proximal humerus. Pain with or without a palpable mass is the most common clinical presentation. It usually has an aggressive growth and may metastasize through the hematogenous route. The lung is the most frequent site of metastasis.
Relationships (44)

Relation Types:
diso_​to_​anat : 16
diso_​to_​diso : 27
diso_​to_​phys : 1


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 7
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​not_​normal_​tissue_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
may_​be_​cytogenetic_​abnormality_​of_​disease : 8
may_​be_​finding_​of_​disease : 4
may_​be_​molecular_​abnormality_​of_​disease : 2
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Bone Tissue C0391978
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell of connective tissue C0009781
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Connective Tissue C0009780
DISO_to_ANATis_associated_anatomic_site_ofimg Connective and Soft Tissue C1516798
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_not_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Connective and Soft Tissue Cell C1708867
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Osteoblast C1518229
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Medullary Bone C1708973
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Connective and Soft Tissue Cell C1513942
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Osteoblast C1514055
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Nerve Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System C1518293
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Osteoblast C0029418
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Skeletal bone C0262950
DISO_to_DISOis_finding_of_diseaseimg Anaplasia C0002793
DISO_to_DISOis_finding_of_diseaseimg Cellular Pleomorphism C1707333
DISO_to_DISOisaimg Childhood Conventional Osteosarcoma C1332974
DISO_to_DISOisaimg Chondroblastic Osteogenic Sarcoma C0279603
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Double Minutes C1512047
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg FOS Gene Amplification C1515561
DISO_to_DISOisaimg Fibroblastic Osteogenic Sarcoma C0279602
DISO_to_DISOmay_be_finding_of_diseaseimg Fractures, Spontaneous C0016663
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 1 C1517379
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanTP537157tumor protein p53
img GENERIF, Score=886, Pubmed Id: 15310147, UMLKSK CUI: C1266166
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1266166Central Osteosarcoma0self