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Details
Link-It Detail - Disease - Metaplastic Carcinoma
Debug Stats
  • ### Total Build Time: 9 ms 21.276 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 340 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 701 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=4 ms Completed: 4 ms rowSize= 7.871 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 11.163 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Metaplastic Carcinoma C1266089
Definition (1)
A general term used to describe carcinomas arising from epithelial cells that have been transformed into another cells type (metaplastic epithelial cells). A representative example is the adenocarcinoma arising in Barrett esophagus. This term is also used to describe carcinomas in which the malignant epithelial cells show differentiation towards another cell type. A representative example of the latter is the metaplastic breast carcinoma in which the malignant glandular cells show squamous, spindle cell, or chondroid/osseous differentiation.
Relationships (15)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 8


Relationships:
is_​abnormal_​cell_​of_​disease : 3
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
isa : 4
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_DISOis_finding_of_diseaseimg 73 METAPLASIAS C0025568
DISO_to_DISOisaimg Adenocarcinoma - intestinal type C0334279
DISO_to_DISOisaimg Barrett's Adenocarcinoma C1332460
DISO_to_DISOisaimg Bladder Squamous Cell Carcinoma C0279681
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOisaimg Carcinosarcomatous squamous cell carcinoma C1275874
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOis_not_finding_of_diseaseimg Metaplasia of Malignant Cells Present C1881799
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanTP638626tumor protein p63
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img GENERIF, Score=983, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 12493033, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
img NCI, Score=801, Pubmed Id: 15489655, UMLKSK CUI: C1266089
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 9110298, UMLKSK CUI: C1266089
HumanCD994267CD99 molecule
img NCI, Score=801, Pubmed Id: 11903575, UMLKSK CUI: C1266089
HumanMGMT4255O-6-methylguanine-DNA methyltransferase
img GENERIF, Score=672, Pubmed Id: 19027227, UMLKSK CUI: C1266089
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1266089Metaplastic Carcinoma0self