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Relationships (15)
Relation Types: diso_to_anat : 10 diso_to_diso : 5
Relationships: is_abnormal_cell_of_disease : 6 is_associated_anatomic_site_of : 2 is_finding_of_disease : 2 is_not_abnormal_cell_of_disease : 1 is_not_finding_of_disease : 1 is_primary_anatomic_site_of_disease : 1 may_be_finding_of_disease : 2 | |
DISO_to_ANAT | | is_abnormal_cell_of_disease |
Cancer Cell C0334227 | DISO_to_ANAT | | is_primary_anatomic_site_of_disease |
Female Reproductive System C0700038 | DISO_to_ANAT | | is_abnormal_cell_of_disease |
Malignant Cytotrophoblastic Cell C1708870 | DISO_to_ANAT | | is_abnormal_cell_of_disease |
Malignant Intermediate Type Trophoblastic Cell C1881561 | DISO_to_ANAT | | is_not_abnormal_cell_of_disease |
Malignant Round Germ Cell with Glycogen-Rich Cytoplasm and Round Nucleus C1881590 | DISO_to_ANAT | | is_abnormal_cell_of_disease |
Malignant Syncytiotrophoblastic Giant Cell C1708920 | DISO_to_ANAT | | is_abnormal_cell_of_disease |
Neoplastic Cell C0597032 | DISO_to_ANAT | | is_abnormal_cell_of_disease |
Neoplastic Trophoblastic Cell C1514116 | DISO_to_ANAT | | is_associated_anatomic_site_of |
Placenta C0032043 | DISO_to_ANAT | | is_associated_anatomic_site_of |
Reproductive system C1261210 | DISO_to_DISO | | may_be_finding_of_disease |
Hemorrhage C0019080 | DISO_to_DISO | | is_finding_of_disease |
Human Chorionic Gonadotropin Positive Neoplastic Cells Present C1708390 | DISO_to_DISO | | is_not_finding_of_disease |
Mixture of Germ Cell Neoplastic Components Present C1711227 | DISO_to_DISO | | may_be_finding_of_disease |
Necrotic changes (finding) C1334928 | DISO_to_DISO | | is_finding_of_disease |
Pregnancy Complications C0032962 |
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Genes (11)
Species: human : 11 | |
Human | SEC16B | 89866 | SEC16 homolog B (S. cerevisiae) | This cDNA clone was a splicing variant of human RGPR-p117, which derived from human placental choriocarcinoma. | Human | ERVWE1 | 30816 | | Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. | Human | DKK1 | 22943 | dickkopf WNT signaling pathway inhibitor 1 | Together, our data indicate the possible correlation between Dkk-1 and human placental choriocarcinoma and suggest potential applications of Dkk-1 in treatment of human placental choriocarcinomas | Human | NFE2L3 | 9603 | nuclear factor, erythroid 2-like 3 | We generated a NRF3-specific antiserum and identified NRF3 protein in placental choriocarcinoma cells. | Human | ABCG2 | 9429 | ATP-binding cassette, sub-family G (WHITE), member 2 | Progesterone receptor isoforms differentially regulate expression of ABCG2 in placental choriocarcinoma cells | Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | Furthermore, in heterologous (CHO and Lec4 cells) and endogenous (placental choriocarcinoma JAR cells) expression systems, we tested whether glycosyl modification also manipulates the hetero-oligomeric interactions of SERT, specifically with myosin IIA. In the present study, d-fenfluramine was found to be cytotoxic to the serotonin (5-HT) transporter (5-HTT) expressing human placental choriocarcinoma cells. Similar results were obtained using human placental choriocarcinoma (JAR) cells that constitutively express the hSERT at a low level. | Human | SLC1A5 | 6510 | solute carrier family 1 (neutral amino acid transporter), member 5 | Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. | Human | KDR | 3791 | kinase insert domain receptor (a type III receptor tyrosine kinase) | STUDY DESIGN: Messenger RNA levels for vascular endothelial growth factor, flt-1, and KDR were measured by TaqMan real-time polymerase chain reaction in human placental choriocarcinoma cells (BeWo) that were exposed to hypoxia (1% oxygen, 5% carbon dioxide, 94% nitrogen) and in placental tissue of neonates with birth asphyxia (n = 20), newborn infants of mothers with preeclampsia (n = 20), and gestational age-matched control subjects. | Human | NR6A1 | 2649 | nuclear receptor subfamily 6, group A, member 1 | RTR mRNA was expressed in the human placental choriocarcinoma cell lines BeWo, JAR, and JEG-3 In this study, we examine the expression of RTR in murine placenta and several human placental choriocarcinoma cell lines. RTR mRNA was also expressed in rat choriocarcinoma Rcho-1 cells and in the human placental choriocarcinoma cell lines BeWo, JAR, and JEG-3. | Human | FLT1 | 2321 | fms-related tyrosine kinase 1 | STUDY DESIGN: Messenger RNA levels for vascular endothelial growth factor, flt-1, and KDR were measured by TaqMan real-time polymerase chain reaction in human placental choriocarcinoma cells (BeWo) that were exposed to hypoxia (1% oxygen, 5% carbon dioxide, 94% nitrogen) and in placental tissue of neonates with birth asphyxia (n = 20), newborn infants of mothers with preeclampsia (n = 20), and gestational age-matched control subjects. | Human | PLIN2 | 123 | perilipin 2 | Data demonstrate that adipose differentiation-related protein (ADRP) mRNA and protein are regulated by fatty acids in a human placental choriocarcinoma cell line (BeWo) and in primary human trophoblasts |
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