Human | PROZ | 8858 | protein Z, vitamin K-dependent plasma glycoprotein | Blood levels of protein Z measured within 7 days of acute stroke were significantly higher in cases than in controls (geometric mean, 1.46 versus 1.16 microg/mL; P<0.0001, consistent with its importance in ischemic stroke or as an acute phase reactant |
Human | VWF | 7450 | von Willebrand factor | von Willebrand factor antigen and activity are associated with the occurrence of acute ischemic stroke |
Human | TNNT2 | 7139 | troponin T type 2 (cardiac) | NT-proBNP, cTnT, or cTnI do not have roles in acute ischemic stroke when other risk factors are considered |
Human | TNNI3 | 7137 | troponin I type 3 (cardiac) | NT-proBNP, cTnT, or cTnI do not have roles in acute ischemic stroke when other risk factors are considered |
Human | TNF | 7124 | tumor necrosis factor | Ischemic tolerance in acute stroke is associated with increased plasma levels of TNF-alpha in the presence of reduced concentrations of IL-6 |
Human | SELP | 6403 | selectin P (granule membrane protein 140kDa, antigen CD62) | levels of soluble and platelet P-selectin are increased in acute ischemic stroke, indicating a possible role of P-selectin |
Human | PRNP | 5621 | prion protein | Increased plasma PrP(C) reflects an endogenous increase in expression in acute stroke-affected brain tissue |
Human | PLAT | 5327 | plasminogen activator, tissue | Investigation of PAI-1 gene 4G/5G polymorphism frequency and TPA enzyme activity in patients with acute stroke reports that there is no direct relation |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Investigation of the association between PAI-1 gene 4G/5G polymorphism frequency and plasma TPA enzyme activity in patients with acute stroke reports that there is no direct relation |
Human | NPPB | 4879 | natriuretic peptide B | results show that N-terminal-proBNP plasma levels are significantly elevated in acute ischemic stroke NT-proBNP, cTnT, or cTnI do not have roles in acute ischemic stroke when other risk factors are considered The plasma BNP level transiently increased in patients with large artery atherosclerosis independently of heart disease, and reflected infarct volume and the severity of acute ischemic stroke |
Human | LIF | 3976 | leukemia inhibitory factor | Increased LIF expression in peri-infarcted regions and sequestration from the peripheral circulation in acute stroke patients are characteristic of the pathobiological response to ischaemia and tissue damage |
Human | INS | 3630 | insulin | Relation between insulin-like growth factor-1 and insulin resistance in patients with acute stroke |
Human | IL18 | 3606 | interleukin 18 (interferon-gamma-inducing factor) | Plasma IL-18 level is a major independent inflammatory predictor of 90-day major adverse clinical outcomes in acute ischemic stroke patients |
Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | circulating IL-6 may have a role in acute stroke |
Human | IGFBP3 | 3486 | insulin-like growth factor binding protein 3 | IGFBP-3 concentration significantly lower in acute ischemic stroke than in controls |
Human | IGF1 | 3479 | insulin-like growth factor 1 (somatomedin C) | Relation between insulin-like growth factor-1 and insulin resistance in patients with acute stroke |
Human | F3 | 2152 | coagulation factor III (thromboplastin, tissue factor) | whole blood tissue factor procoagulant activity and plasma FVIIa in ten patients with type 2 diabetes mellitus and 11 non-diabetic patients at baseline and 6, 12, 24, and 48 hours (h) after presentation for acute stroke |
Human | EDN1 | 1906 | endothelin 1 | serum ET-1 may have a role in severe brain edema in acute stroke patients treated with t-PA |
Human | DECR1 | 1666 | 2,4-dienoyl CoA reductase 1, mitochondrial | The TT genotype of C677T polymorphism in the MTHFR gene contributes to genetic susceptibility of acute ischemic stroke in a Singapore population |
Human | CRP | 1401 | C-reactive protein, pentraxin-related | Sleep apnea is independently associated with raised levels of CRP and fibrinogen in patients with acute ischemic stroke |
Human | CPB2 | 1361 | carboxypeptidase B2 (plasma) | elevated TAFI antigen levels may be a consequence of an acute phase reaction, and together with a depressed overall fibrinolysis potential suggest impaired fibrinolysis in patients with acute ischemic stroke |
Human | C4B | 721 | complement component 4B (Chido blood group) | platelet C4d is associated with severe acute ischemic stroke; platelet C4d may be a biomarker as well as pathogenic clue that links cerebrovascular inflammation and thrombosis |