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Details
Link-It Detail - Disease - Brain Infarction
Debug Stats
  • ### Total Build Time: 54 ms 41.921 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 499 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=8 ms Completed: 8 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 974 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 997 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.317 KB
  • CONCEPT_RELATIONSHIPS gt=8 ms Completed: 8 ms rowSize= 12.951 KB
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 19.557 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Brain Infarction C0751955
Definition (1)
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Brain Ischemia C0007786
img Stroke C0038454
Children (2)
img Brain Stem Infarctions C0521542
img Cerebral Infarction C0007785
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Brain Ischemia C0007786
img Cardiovascular Diseases C0007222img Vascular Diseases C00423735img Brain Ischemia C0007786
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Stroke C0038454
img Cardiovascular Diseases C0007222img Vascular Diseases C00423735img Stroke C0038454
Relationships (101)

Relation Types:
diso_​to_​anat : 27
diso_​to_​chem : 9
diso_​to_​diso : 54
diso_​to_​phen : 2
diso_​to_​phys : 9


Relationships:
none : 100
entry_​version_​of : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO227img Complication Aspects C1171258
DISO_to_DISO135img Cerebrovascular accident C0038454
DISO_to_DISO132img Complication Aspects C1171258
DISO_to_DISO119img Brain Ischemia C0007786
DISO_to_ANAT99img Brain C0006104
DISO_to_DISO83img Brain Ischemia C0007786
DISO_to_CHEM60img Agents, Neuroprotective C0242912
DISO_to_PHEN55img genetic aspects C0017399
DISO_to_DISO53img Cerebrovascular accident C0038454
DISO_to_ANAT48img Brain C0006104
DISO_to_ANAT45img In Blood C0005768
DISO_to_DISO42img CEREBRAL INFARCT MIDDLE CEREBRAL ARTERY C0740392
DISO_to_ANAT39img Cerebellum C0007765
DISO_to_DISO36img Cognition Disorders C0009241
DISO_to_DISO35img CEREBELLAR ABNORMALITIES C0007760
DISO_to_ANAT33img Thalamic structure C0039729
DISO_to_DISO31img Brain Hypoxia Ischemia C0752308
DISO_to_CHEM30img Agents, Neuroprotective C0242912
DISO_to_DISO28img Degeneration, Nerve C0027746
DISO_to_ANAT27img Cerebellum C0007765
DISO_to_ANAT26img Cerebral Arteries C0007770
DISO_to_ANAT24img In Blood C0005768
DISO_to_ANAT23img Cerebral Cortex C0007776
DISO_to_PHYS23img Functional Laterality C1720777
DISO_to_DISO22img CEREBELLAR ABNORMALITIES C0007760
Genes (67)

Species:
human : 67
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanEGLN154583egl-9 family hypoxia-inducible factor 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanNDUFA1351079NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanSMARCAL150485SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=1000, Pubmed Id: 18096839, UMLKSK CUI: C0751955
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanPROZ8858protein Z, vitamin K-dependent plasma glycoprotein
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanCYP4F28529cytochrome P450, family 4, subfamily F, polypeptide 2
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanTP537157tumor protein p53
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanTLR47099toll-like receptor 4
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanTHBD7056thrombomodulin
img GENERIF, Score=1000, Pubmed Id: 18204921, UMLKSK CUI: C0751955
HumanTBXA2R6915thromboxane A2 receptor
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanTAC16863tachykinin, precursor 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanROS16098c-ros oncogene 1 , receptor tyrosine kinase
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanRELA5970v-rel avian reticuloendotheliosis viral oncogene homolog A
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanPTGIS5740prostaglandin I2 (prostacyclin) synthase
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanPRNP5621prion protein
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanPRKCH5583protein kinase C, eta
img GENERIF, Score=861, Pubmed Id: 18164711, UMLKSK CUI: C0751955
HumanPON15444paraoxonase 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanSERPINE25270serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanPDE4D5144phosphodiesterase 4D, cAMP-specific
img GAD, Score=1000, Pubmed Id: 16322495, UMLKSK CUI: C0751955
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanNFKB14790nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
INFERRED, Score=800, UMLKSK CUI: C0751955
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
INFERRED, Score=800, UMLKSK CUI: C0751955
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0751955Brain Infarction0self