Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | The 14 kDa circulating ZIP from normal pregnancies suppressed components within the JAK/STAT pathway and induced suppressors of cytokine stimulation, SOCS2.[zeta inhibitor protein] |
Human | ERAP2 | 64167 | endoplasmic reticulum aminopeptidase 2 | oxytocinase subfamily of M1 aminopeptidases play important roles in the maintenance of homeostasis including maintenance of normal pregnancy, memory retention, blood pressure regulation and antigen presentation [review] |
Human | ERAP1 | 51752 | endoplasmic reticulum aminopeptidase 1 | oxytocinase subfamily of M1 aminopeptidases play important roles in the maintenance of homeostasis including maintenance of normal pregnancy, memory retention, blood pressure regulation and antigen presentation [review] |
Human | LGALS13 | 29124 | lectin, galactoside-binding, soluble, 13 | Maternal serum PP13 concentration in the first trimester was significantly lower in patients who developed preterm and early-onset preeclampsia than in those with normal pregnancies |
Human | PIBF1 | 10464 | progesterone immunomodulatory binding factor 1 | PIBF production is a characteristic feature of normal pregnancy, and determination of PIBF concentration in urine might be of use for the diagnosis of threatened premature pregnancy termination |
Human | PROZ | 8858 | protein Z, vitamin K-dependent plasma glycoprotein | The median maternal plasma protein Z concentration was significantly lower in patients with pyelonephritis during pregnancy than in patients with normal pregnancies data show a progressive increase in protein Z levels with gestational age in normal pregnancies and a return to normal levels around 6 to 12 weeks postpartum |
Human | VWF | 7450 | von Willebrand factor | studied a group of healthy non-bleeding women to evaluate normal ranges OF F8 and VWF and their relationship to blood group and parity in normal pregnancy, and the return to non-pregnant factor levels in puerperium |
Human | TNF | 7124 | tumor necrosis factor | increased tumor necrosis factor-alpha and leptin levels may contribute to insulin resistance in gestational diabetes mellitus and in the third trimester of normal pregnancy and may negatively influence the anthropometric parameters of the newborns tumor necrosis factor-alpha may contribute to the insulin resistance during the course of normal pregnancy AHSG, TNF-alpha and leptin may contribute to insulin resistance during normal pregnancy and gestational diabetes the pathophysiological role of the tumor necrosis factor (TNF) system in insulin resistance in patients with gestational diabetes (GDM) and during the course of normal pregnancy |
Human | TEK | 7010 | TEK tyrosine kinase, endothelial | Patients with preeclampsia and those with small-for-gestational-age fetuses have lower plasma soluble Tie-2 than women with normal pregnancies |
Human | TAC3 | 6866 | tachykinin 3 | NKB plays a role in the maintenance of high placental blood flow in normal pregnancy |
Human | SPP1 | 6696 | secreted phosphoprotein 1 | Compared with normal pregnancy, osteopontin expression and decidual killer cells accumulation were reduced significantly in recurrent pregnancy loss patients |
Human | CCL5 | 6352 | chemokine (C-C motif) ligand 5 | RANTES levels in blood, quantities released from platelets ex vivo, and quantities released from SFFLRN stimulated platelets ex vivo were compared for preeclamptic and normal pregnancies |
Human | PGF | 5228 | placental growth factor | patients destined to develop preeclampsia and those who delivered a small for gestational age neonate had lower plasma concentrations of placental grwoth factor (PlGF) than those with a normal pregnancy throughout gestation |
Human | LNPEP | 4012 | leucyl/cystinyl aminopeptidase | oxytocinase subfamily of M1 aminopeptidases play important roles in the maintenance of homeostasis including maintenance of normal pregnancy, memory retention, blood pressure regulation and antigen presentation [review] |
Human | LEP | 3952 | leptin | increased tumor necrosis factor-alpha and leptin levels may contribute to insulin resistance in gestational diabetes mellitus and in the third trimester of normal pregnancy and may negatively influence the anthropometric parameters of the newborns AHSG, TNF-alpha and leptin may contribute to insulin resistance during normal pregnancy and gestational diabetes |
Human | IL10 | 3586 | interleukin 10 | elevated IL-10 is a physiological consequence of normal healthy pregnancy |
Human | HSPA8 | 3312 | heat shock 70kDa protein 8 | serum Hsp70 concentrations are decreased in normal human pregnancy |
Human | HSPA6 | 3310 | heat shock 70kDa protein 6 (HSP70B') | higher expression of HSPA6 & HSPA1A was exhibited in placental vascular disease (PVD)subjects compared to normal pregnancy; significant upregulation of HSP70 mRNA & protein in placental tissue & microvascular endothelial cells of PVD subjects was observed |
Human | HSPA1A | 3303 | heat shock 70kDa protein 1A | higher expression of HSPA6 & HSPA1A was exhibited in placental vascular disease (PVD)subjects compared to normal pregnancy; significant upregulation of HSP70 mRNA & protein in placental tissue & microvascular endothelial cells of PVD subjects was observed |
Human | CXCL1 | 2919 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | GRO-alpha levels in blood, quantities released from platelets ex vivo, and quantities released from SFFLRN stimulated platelets ex vivo were compared for preeclamptic and normal pregnancies |
Human | F8 | 2157 | coagulation factor VIII, procoagulant component | studied a group of healthy non-bleeding women to evaluate normal ranges OF F8 and VWF and their relationship to blood group and parity in normal pregnancy, and the return to non-pregnant factor levels in puerperium |
Human | F3 | 2152 | coagulation factor III (thromboplastin, tissue factor) | expression on monocyte subpopulations during normal pregnancy |
Human | F2 | 2147 | coagulation factor II (thrombin) | Endogenous thrombin potential does increase with duration of normal uncomplicated pregnancy |
Human | ELN | 2006 | elastin | Elastin degradation is decreased during normal pregnancy |
Human | EGF | 1950 | epidermal growth factor | This study shows that apoptosis may be induced in villous trophoblast following exposure to ROS, and demonstrates the anti-apoptotic effect of EGF in trophoblast, the maintenance of which is essential for normal pregnancy |