Human | CD24 | 100133941 | CD24 molecule | N-glycans of the mouse glycoprotein HSA and its human analogue CD24 from lymphoblastoma, neuroblastoma and astrocytoma cell lines as well as from mouse brain homogenate were analysed and compared to each other |
Human | MIR34A | 407040 | microRNA 34a | study demonstrates one important regulatory role of miR-34a in cell growth and MYCN suppression in neuroblastoma miR-34a is a tumor suppressor gene in human neuroblastoma |
Human | FLJ22536 | 401237 | | We observed a significant association between neuroblastoma and the common minor alleles of three consecutive single-nucleotide polymorphisms (SNPs) at chromosome band 6p22 and containing the predicted genes FLJ22536 and FLJ44180 |
Human | APITD1 | 378708 | apoptosis-inducing, TAF9-like domain 1 | Mutations in APITD1 is not a common abnormality of neuroblastoma tumours |
Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | The characteristic expression pattern of DEIN suggests a specific role of this gene in the unique biology of stage IVS tumors and may help to molecularly define this special subtype of neuroblastoma[DEIN] |
Human | NCOA7 | 135112 | nuclear receptor coactivator 7 | present findings indicate that ERAP140/Nbla10993 plays an important role in the regulation of ATRA-mediated neuronal differentiation, and is a novel member of prognostic indicators for neuroblastoma |
Human | SCGB3A1 | 92304 | secretoglobin, family 3A, member 1 | CASP8, DCR2, and HIN-1 methylation leads to progression of neuroblastoma |
Human | PROK1 | 84432 | prokineticin 1 | EG-VEGF/Prok-1 signaling has a role in neuroblastoma progression |
Human | LRRN1 | 57633 | leucine rich repeat neuronal 1 | N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma |
Human | LMO3 | 55885 | LIM domain only 3 (rhombotin-like 2) | The deregulated expression of neuronal-specific LMO3 and HEN2 contributes to the genesis and progression of human neuroblastoma in a lineage-specific manner |
Human | DNAJC11 | 55735 | DnaJ (Hsp40) homolog, subfamily C, member 11 | no evidence for somatic mutations in CAMTA1 in neuroblastoma FLJ10737 and CAMTA1 genes on 1p36.31-p36.23 are candidate tumor suppressor genes of neuroblastoma |
Human | SHC3 | 53358 | SHC (Src homology 2 domain containing) transforming protein 3 | ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase |
Human | ZMYND10 | 51364 | zinc finger, MYND-type containing 10 | These data suggest a significant role for epigenetic inactivation of BLU in the pathogenesis of common human cancers and that methylation inactivation of BLU occurs independent of RASSF1A in SCLC and neuroblastoma tumours |
Human | FZR1 | 51343 | fizzy/cell division cycle 20 related 1 (Drosophila) | Retinoic acid downregulates Rae1, hence facilitating APC(Cdh1)-mediated Skp2 degradation leading to the arrest of cell cycle progression and neuroblastoma differentiation |
Human | BBC3 | 27113 | BCL2 binding component 3 | BBC3 mediates fenretinide-induced cell death in neuroblastoma |
Human | WSB1 | 26118 | WD repeat and SOCS box containing 1 | WSB1 shows strong correlations between expression level and copy number, and also enhances the prognostic prediction when combined with other current prognostic factors in neuroblastoma |
Human | CADM1 | 23705 | cell adhesion molecule 1 | TSLC1 acts as a candidate tumor suppressor gene for neuroblastoma Downregulation of CADM1 tumour suppressor gene expression is a critical event in neuroblastoma pathogenesis resulting in tumour progression and unfavourable patient outcome |
Human | PRAME | 23532 | preferentially expressed antigen in melanoma | PRAME is highly expressed in primary advanced neuroblastoma |
Human | CAMTA1 | 23261 | calmodulin binding transcription activator 1 | FLJ10737 and CAMTA1 genes on 1p36.31-p36.23 are candidate tumor suppressor genes of neuroblastoma no evidence for somatic mutations in FLJ10737 in neuroblastoma |
Human | KIF1B | 23095 | kinesin family member 1B | KIF1Ba in addition to KIF1Bbeta may not be a candidate tumor suppressor gene for neuroblastoma KIF1Bbeta may act as a haploinsufficient tumor suppressor, and its allelic loss may be involved in the pathogenesis of neuroblastoma and other cancers Neuroblastoma, arises anywhere along the sympathetic chain (including intracranially) |
Human | PRAF2 | 11230 | PRA1 domain family, member 2 | PRAF2 has a role in progression of neuroblastoma |
Human | PTP4A3 | 11156 | protein tyrosine phosphatase type IVA, member 3 | In tumor cells, PRL-3 mRNA levels varied markedly with high expression in SKNAS neuroblastoma, MCF-7 and BT474 breast carcinoma, Hep3B hepatocellular carcinoma, and HCT116 colon carcinoma |
Human | TMSB15A | 11013 | thymosin beta 15a | Human thymosin beta neuroblastoma has a higher affinity for actin in comparison to thymosin beta4 and promotes cell migration |
Human | NES | 10763 | nestin | nestin may be one mediator of N-myc-associated tumor aggressiveness of human neuroblastoma |
Human | ABCC4 | 10257 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | MRP4 may have a role in MYCN oncogene amplification and in drug resistance in neuroblastoma |