Human | CD209 | 30835 | CD209 molecule | findings support previous data showing that VDR SNPs modulate the risk for pulmonary tuberculosis in West Africans and suggest that variation within DC-SIGN and PTX3 also affect the disease outcome |
Human | PHLDA1 | 22822 | pleckstrin homology-like domain, family A, member 1 | Reduced PHLDA1 expression is important in breast cancer progression and could serve as useful prognostic marker of disease outcome |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Analysis of VEGF gene polymorphisms can help identify patient subgroups at high risk of a poor disease outcome and survival in gastric cancers |
Human | VDR | 7421 | vitamin D (1,25- dihydroxyvitamin D3) receptor | findings support previous data showing that VDR SNPs modulate the risk for pulmonary tuberculosis in West Africans and suggest that variation within DC-SIGN and PTX3 also affect the disease outcome |
Human | TNF | 7124 | tumor necrosis factor | Among host genetic factors contributing to H. pylori disease outcome, TNF-A -857 TT genotype favors duodenal ulcer |
Human | TERT | 7015 | telomerase reverse transcriptase | study identifies hTERT-RNA level as a new prognostic marker in B-cell chronic lymphocytic leukemia, and may be used to identify previously unrecognized patient groups with the same IgVH mutation status and different disease outcomes |
Human | CXCL12 | 6387 | chemokine (C-X-C motif) ligand 12 | The CXCL12-G801A polymorphism did not associate with disease outcome or presence of extramedullary disease in acute myeloid leukemia |
Human | PTX3 | 5806 | pentraxin 3, long | findings support previous data showing that VDR SNPs modulate the risk for pulmonary tuberculosis in West Africans and suggest that variation within DC-SIGN and PTX3 also affect the disease outcome |
Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | COX-2 expression was not correlated with clinicopathological characteristics of colon carcinoma and disease outcome |
Human | MYOD1 | 4654 | myogenic differentiation 1 | Hypermethylation of MYOD1 is statistically significantly associated with poor disease outcome in cervical cancer |
Human | MN1 | 4330 | meningioma (disrupted in balanced translocation) 1 | leukemogenic effect of MN1-ets variant gene 6 L in our knock-in mice is pleiotropic, and the type of secondary mutation determines disease outcome |
Human | IL10 | 3586 | interleukin 10 | Among host genetic factors contributing to H. pylori disease outcome, IL-10 -819 TT genotype favors intestinal metaplasia and non-cardia gastric cancer |
Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | Results suggests that IL-6 may be a reliable marker of disease outcome in studies based on novel approaches aiming at modifying age- and cancer-related biologic mechanisms there appeared to be no significant associations between IL6 promoter variants and disease outcome in chronic hepatitis B |
Human | IGF2 | 3481 | insulin-like growth factor 2 (somatomedin A) | IGF2 helps predict disease outcome in GIST patients |
Human | IGF1 | 3479 | insulin-like growth factor 1 (somatomedin C) | IGF1 helps predict disease outcome in GIST patients |
Human | IFNG | 3458 | interferon, gamma | Among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections |
Human | GSTM1 | 2944 | glutathione S-transferase mu 1 | GSTM1 polymorphism may be a valuable molecular marker for predicting disease outcome in ovarian cancer patient |
Human | FLT3 | 2322 | fms-related tyrosine kinase 3 | no correlation between size of duplicated sequences of FLT3 and disease outcome in acute myeloid leukemia patients |
Human | ETV6 | 2120 | ets variant 6 | leukemogenic effect of meningioma 1-TEL in our knock-in mice is pleiotropic, and the type of secondary mutation determines disease outcome |
Human | ERBB2 | 2064 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | The review evaluates the status of serum-based testing for circulating HER-2/neu receptor protein and its ability to predict disease outcome and therapy response Results suggest that the currently identified genetic polymorphisms of HER-2 are not associated with an increased risk of breast cancer in Korean women, whereas one haplotype does affect protein expression of the tumor and disease outcome |
Human | DAPK1 | 1612 | death-associated protein kinase 1 | The promoter hypermethylation of DAPK-1 is a marker of aggressive renal cell carcinoma and provides independent prognostic information on disease outcome |
Human | CDH13 | 1012 | cadherin 13 | Hypermethylation of CDH13 is statistically significantly associated with poor disease outcome in cervical cancer |
Human | BRAF | 673 | v-raf murine sarcoma viral oncogene homolog B | BRAF mutation may be acquired during development of metastasis but is not a significant factor for primary melanoma development and disease outcome |
Human | BCL2 | 596 | B-cell CLL/lymphoma 2 | The level of bcl-2 expression could be a valuable predictor of tumor behavior and disease outcome |
Human | APAF1 | 317 | apoptotic peptidase activating factor 1 | The promoter hypermethylation of APAF-1 is a marker of aggressive renal cell carcinoma and provides independent prognostic information on disease outcome Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma |