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Details
Link-It Detail - Disease - CARCINOMA OF VULVA
Debug Stats
  • ### Total Build Time: 26 ms 40.636 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 498 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=6 ms Completed: 6 ms rowSize= 10.698 KB
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 27.902 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
CARCINOMA OF VULVA C0677055
Definition (1)
A carcinoma arising from the vulva. It usually affects elderly women but has been observed in premenopausal women as well. The most frequently seen histologic type is squamous cell carcinoma. The most common site of involvement is the labia majora. In many cases, the development of vulvar cancer is preceded by condyloma or squamous dysplasia.
Relationships (23)

Relation Types:
diso_​to_​anat : 11
diso_​to_​diso : 12


Relationships:
is_​abnormal_​cell_​of_​disease : 4
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 2
isa : 10
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_associated_anatomic_site_ofimg Vulva C0042993
DISO_to_DISOisaimg Adenocarcinoma of Vulva C1336975
DISO_to_DISOisaimg Bartholin Gland Carcinoma C0349561
DISO_to_DISOisaimg Basal Cell Carcinoma of Vulva C1336977
DISO_to_DISOisaimg CA - Squamous cell carcinoma of vulva C0280856
DISO_to_DISOisaimg Carcinoma of Clitoris C1333070
DISO_to_DISOisaimg Carcinoma of Labia Majora C1334356
DISO_to_DISOisaimg Carcinoma of Labia Minora C1334357
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOisaimg Recurrent Cancer of Vulva C0278734
DISO_to_DISOisaimg Vulvar Carcinoma by AJCC v6 Stage C2983571
DISO_to_DISOisaimg Vulvar Carcinoma by AJCC v7 Stage C2984069
Genes (20)

Species:
human : 20
SpeciesGeneGeneIdGene NameEvidence
HumanLY6D8581lymphocyte antigen 6 complex, locus D
img NCI, Score=801, Pubmed Id: 1989663, UMLKSK CUI: C0677055
HumanWRN7486Werner syndrome, RecQ helicase-like
img NCI, Score=801, Pubmed Id: 10206685, UMLKSK CUI: C0677055
img NCI, Score=801, Pubmed Id: 10206685, UMLKSK CUI: C0677055
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 12445188, UMLKSK CUI: C0677055
HumanRBL25934retinoblastoma-like 2 (p130)
img NCI, Score=801, Pubmed Id: 11172288, UMLKSK CUI: C0677055
img NCI, Score=801, Pubmed Id: 11172288, UMLKSK CUI: C0677055
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 17413988, UMLKSK CUI: C0677055
img GENERIF, Score=1000, Pubmed Id: 17404027, UMLKSK CUI: C0677055
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GAD, Score=1000, Pubmed Id: 15196865, UMLKSK CUI: C0677055
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
img GENERIF, Score=734, Pubmed Id: 15870899, UMLKSK CUI: C0677055
HumanMMP134322matrix metallopeptidase 13 (collagenase 3)
img NCI, Score=801, Pubmed Id: 10027405, UMLKSK CUI: C0677055
img NCI, Score=801, Pubmed Id: 10027405, UMLKSK CUI: C0677055
HumanMLH14292mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
img GENERIF, Score=734, Pubmed Id: 15870899, UMLKSK CUI: C0677055
HumanKRT133860keratin 13
img NCI, Score=801, Pubmed Id: 2483837, UMLKSK CUI: C0677055
HumanJUN3725jun proto-oncogene
img NCI, Score=801, Pubmed Id: 10996384, UMLKSK CUI: C0677055
img NCI, Score=801, Pubmed Id: 10996384, UMLKSK CUI: C0677055
HumanIVL3713involucrin
img NCI, Score=801, Pubmed Id: 8625158, UMLKSK CUI: C0677055
HumanIL63569interleukin 6 (interferon, beta 2)
img GAD, Score=1000, Pubmed Id: 16198606, UMLKSK CUI: C0677055
HumanIL1RN3557interleukin 1 receptor antagonist
img NCI, Score=801, Pubmed Id: 14984963, UMLKSK CUI: C0677055
img GAD, Score=1000, Pubmed Id: 14984963, UMLKSK CUI: C0677055
HumanIL1B3553interleukin 1, beta
img GAD, Score=1000, Pubmed Id: 14984963, UMLKSK CUI: C0677055
HumanIL1A3552interleukin 1, alpha
img GAD, Score=1000, Pubmed Id: 14984963, UMLKSK CUI: C0677055
HumanFGF42249fibroblast growth factor 4
img NCI, Score=801, Pubmed Id: 3290903, UMLKSK CUI: C0677055
HumanCRP1401C-reactive protein, pentraxin-related
img GENERIF, Score=1000, Pubmed Id: 17459567, UMLKSK CUI: C0677055
HumanCDKN1B1027cyclin-dependent kinase inhibitor 1B (p27, Kip1)
img GENERIF, Score=884, Pubmed Id: 16474380, UMLKSK CUI: C0677055
HumanCA9768carbonic anhydrase IX
img GENERIF, Score=734, Pubmed Id: 15856466, UMLKSK CUI: C0677055
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0677055CARCINOMA OF VULVA0self