Human | CSAG2 | 728461 | CSAG family, member 2 | As the TRAG-3 gene is located on Xq28, which is the same locus as the MAGE gene family, we found a frequent synchronous expression pattern with TRAG-3 and MAGE-3 in esophageal cancer |
Human | MIR196A1 | 406972 | microRNA 196a-1 | demonstrated a novel mechanism of post-transcriptional regulation of ANXA1 expression and identified miR-196a as a marker of esophageal cancer |
Human | TMPRSS11A | 339967 | transmembrane protease, serine 11A | findings indicate that ECRG1 may be a candidate tumor suppressor gene for esophageal cancer involved in cell-cycle control |
Human | EMILIN3 | 90187 | elastin microfibril interfacer 3 | Might play important roles in carcinogenesis of esophageal cancer |
Human | SPINK7 | 84651 | serine peptidase inhibitor, Kazal type 7 (putative) | Short tandem repeat polymorphism in a novel esophageal cancer-related gene (ECRG2) implicates susceptibility to esophageal cancer Data suggest that the physical interaction of esophageal cancer related gene 2 (ECRG2) and metallothionein 2A (MT2A) may play an important role in the carcinogenesis of esophageal cancer genetically fixed short tandem repeat polymorphism TCA3/TCA3 in exon 4 of ECRG2 is associated with poor clinical outcome in surgically treated esophageal cancer patients and might be a potential prognostic marker |
Human | C2orf40 | 84417 | chromosome 2 open reading frame 40 | Significantly lower expression of esophageal cancer-related gene 4 is associated with esophageal squamous cell carcinoma |
Human | PDCD1LG2 | 80380 | programmed cell death 1 ligand 2 | Data suggest that PD-L2 status may be a new predictor of prognosis for patients with esophageal cancer |
Human | RNF34 | 80196 | ring finger protein 34, E3 ubiquitin protein ligase | a novel gene, hRFI, preferentially expressed in esophageal cancer (hRFI) |
Human | RSRC2 | 65117 | arginine/serine-rich coiled-coil 2 | RSRC2 might play a role in cell proliferation and progression of esophageal cancer |
Human | ADAMTS9 | 56999 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | this study identifies and provides functional evidence for a critical region associated with tumor suppression on 3p14.2 and provides the first evidence that ADAMTS9, mapping to this region, may contribute to esophageal cancer development |
Human | CHFR | 55743 | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | expression is downregulated by CpG island hypermethylation in esophageal cancer |
Human | SPA17 | 53340 | sperm autoantigenic protein 17 | Overexpression of sperm protein 17 is associated with esophageal cancer |
Human | WWOX | 51741 | WW domain containing oxidoreductase | |
Human | DEC1 | 50514 | deleted in esophageal cancer 1 | |
Human | CD274 | 29126 | CD274 molecule | Data suggest that PD-L1 status may be a new predictor of prognosis for patients with esophageal cancer |
Human | DROSHA | 29102 | drosha, ribonuclease type III | We found that RNASEN expression levels were enhanced in a fraction of esophageal cancers |
Human | PABPC1 | 26986 | poly(A) binding protein, cytoplasmic 1 | In esophageal cancer, reduced expression of PABPC1 was correlated with local tumor progression and poor prognosis after surgery |
Human | TMEFF2 | 23671 | transmembrane protein with EGF-like and two follistatin-like domains 2 | Hypermethylation of p16, RUNX3, and HPP1 in Barreett exophagus may represent independent risk factors for the progression of Barrett esophagus to esophageal cancer |
Human | LZTS1 | 11178 | leucine zipper, putative tumor suppressor 1 | |
Human | HPSE | 10855 | heparanase | The expression of heparanase mRNA in an esophageal cancer cell line can be inhibited by antisense oligonucleotides, which can inhibit metastasis of esophageal squamous cell carcinoma or other tumors by inhibiting the expression of heparanase |
Human | FRAT1 | 10023 | frequently rearranged in advanced T-cell lymphomas | Aberrant activation of beta-catenin/TCF pathway in esophageal cancer appears to be due to upstream events such as FRAT1 overexpression, and c-Myc may be an important element in oncogenesis of human ESCC induced by FRAT1 |
Human | DLEC1 | 9940 | deleted in lung and esophageal cancer 1 | |
Human | KLF4 | 9314 | Kruppel-like factor 4 (gut) | down-regulation of gut-enriched Kruppel-like factor in esophageal squamous cancer |
Human | CLDN1 | 9076 | claudin 1 | Claudin-1 expression is correlated with recurrence status and poor prognosis in esophageal cancer |
Human | MBD4 | 8930 | methyl-CpG binding domain protein 4 | Title:Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma|Association:Not Found|Conclusion:The results suggest that the polymorphisms in five BER genes may be associated with the susceptibility to ESCC in a Chinese population. |