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Details
Link-It Detail - Disease - Leukemia, Prolymphocytic, B-Cell
Debug Stats
  • ### Total Build Time: 240 ms 34.223 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 342 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 994 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 7.904 KB
  • CONCEPT_RELATIONSHIPS gt=216 ms Completed: 216 ms rowSize= 15.462 KB
  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 7.814 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia, Prolymphocytic, B-Cell C0475801
Definition (1)
A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Leukemia, Prolymphocytic C0023486
img Leukemia, B-Cell C2004493
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, Prolymphocytic C0023486
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Leukemia, Prolymphocytic C0023486
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Leukemia, Prolymphocytic C0023486
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, B-Cell C2004493
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Leukemia, B-Cell C2004493
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Leukemia, B-Cell C2004493
Relationships (38)

Relation Types:
diso_​to_​anat : 24
diso_​to_​diso : 12
diso_​to_​phen : 2


Relationships:
none : 3
is_​abnormal_​cell_​of_​disease : 9
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 6
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 3
isa : 1
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 3
may_​be_​finding_​of_​disease : 2
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN4img genetic aspects C0017399
DISO_to_ANAT3img In Blood C0005768
DISO_to_DISO3img Complication Aspects C1171258
DISO_to_ANATis_abnormal_cell_of_diseaseimg Atypical lymphocyte C0221277
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg B lymphoblast C1516097
DISO_to_ANATis_normal_cell_origin_of_diseaseimg B-Lymphocytes C0004561
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Bone Marrow C0005953
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Cell C1517806
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Lymphocyte C1517808
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Lymphatic System C0024235
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lymphatic Tissue C0024296
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Lymphocyte C0024264
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature B-Cell C1513019
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Mature Lymphocyte C1513026
DISO_to_ANATis_not_normal_cell_origin_of_diseaseimg Myeloid Cells C0887899
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic B-Lymphocyte C1513929
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic B-Prolymphocyte C1513930
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Lymphocyte C1514011
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Prolymphocyte C1514073
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell C1514110
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanTCL1A8115T-cell leukemia/lymphoma 1A
img NCI, Score=801, Pubmed Id: 3282128, UMLKSK CUI: C0475801
HumanRAB1A5861RAB1A, member RAS oncogene family
img NCI, Score=801, Pubmed Id: 3531732, UMLKSK CUI: C0475801
HumanITGB23689integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
img NCI, Score=801, Pubmed Id: 1373000, UMLKSK CUI: C0475801
HumanITGAL3683integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
img NCI, Score=801, Pubmed Id: 1373000, UMLKSK CUI: C0475801
HumanFMOD2331fibromodulin
img NCI, Score=801, Pubmed Id: 15741214, UMLKSK CUI: C0475801
HumanMS4A1931membrane-spanning 4-domains, subfamily A, member 1
img NCI, Score=801, Pubmed Id: 12969808, UMLKSK CUI: C0475801
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0475801Leukemia, Prolymphocytic, B-Cell0self