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Details
Link-It Detail - Disease - Anti-Glomerular Basement Membrane Disease
Debug Stats
  • ### Total Build Time: 53 ms 28.607 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 587 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.403 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 5.371 KB
  • CONCEPT_RELATIONSHIPS gt=23 ms Completed: 23 ms rowSize= 13.808 KB
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 5.688 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.175 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Anti-Glomerular Basement Membrane Disease C0403529
Definition (1)
An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Lung Diseases, Interstitial C0206062
img Glomerulonephritis C0017658
img Autoimmune Diseases C0004364
Ancestral Roots
RootRoot Plus OneDepthParent
img Respiratory Tract Diseases C0035242img Lung Diseases C00241154img Lung Diseases, Interstitial C0206062
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img Glomerulonephritis C0017658
img Male Urogenital Diseases C1720894img Urologic Diseases C00420756img Glomerulonephritis C0017658
img Immune System Diseases C0021053img Autoimmune Diseases C00043643img Autoimmune Diseases C0004364
Relationships (35)

Relation Types:
diso_​to_​anat : 7
diso_​to_​chem : 9
diso_​to_​diso : 15
diso_​to_​gene : 2
diso_​to_​phen : 2


Relationships:
none : 21
associated_​with : 5
classifies : 1
clinically_​similar : 2
gene_​associated_​with_​disease : 2
gene_​product_​malfunction_​associated_​with_​disease : 1
location_​of : 1
mapped_​to : 1
sort_​version_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO41img Complication Aspects C1171258
DISO_to_CHEM31img Abs - Autoantibodies C0004358
DISO_to_DISO23img Complication Aspects C1171258
DISO_to_PHEN21img genetic aspects C0017399
DISO_to_CHEM18img Collagen Type IV C0009333
DISO_to_CHEM17img Antibodies, Antineutrophil Cytoplasmic C0103647
DISO_to_CHEM16img Autoantigens C0004359
DISO_to_CHEM16img Collagen Type IV C0009333
DISO_to_ANAT15img Kidney C0022646
DISO_to_ANAT15img Kidney Glomerulus C0022663
DISO_to_CHEM15img Abs - Autoantibodies C0004358
DISO_to_CHEM15img Antigens, Autologous C0004359
DISO_to_CHEM14img Antibodies C0003241
DISO_to_DISO14img Glomerulonephritis C0017658
DISO_to_ANAT13img Glomerular Basement Membrane C0599297
DISO_to_PHEN13img genetic aspects C0017399
DISO_to_ANAT12img In Blood C0005768
DISO_to_ANAT10img Kidney C0022646
DISO_to_DISO10img Lung Diseases C0024115
DISO_to_ANAT9img In Blood C0005768
DISO_to_DISO9img Glomerulonephritis C0017658
DISO_to_ANATlocation_ofimg Lung C0024109
DISO_to_CHEMgene_product_malfunction_associated_with_diseaseimg Col4A3 protein, human C1314894
DISO_to_DISOsort_version_ofimg Anti-Glomerular Basement Membrane Disease C0403529
DISO_to_DISOclinically_similarimg GOODPASTURE SYNDROME C0519009
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanCOL4A3BP10087collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
img GENERIF, Score=1000, Pubmed Id: 18216317, UMLKSK CUI: C0403529
HumanHLA-DRB13123
img GENERIF, Score=911, Pubmed Id: 18413431, UMLKSK CUI: C0403529
img GAD, Score=1000, Pubmed Id: 15199166, UMLKSK CUI: C0403529
HumanCOL4A31285collagen, type IV, alpha 3 (Goodpasture antigen)
img GENERIF, Score=1000, Pubmed Id: 18499662, UMLKSK CUI: C0403529
img GENERIF, Score=673, Pubmed Id: 18941198, UMLKSK CUI: C0403529
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0403529Anti-Glomerular Basement Membrane Disease0self