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Details
Link-It Detail - Disease - Renal Insufficiency, Chronic
Debug Stats
  • ### Total Build Time: 40 ms 46.883 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 412 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 579 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 561 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 2.819 KB
  • CONCEPT_RELATIONSHIPS gt=20 ms Completed: 20 ms rowSize= 12.652 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 27.980 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Renal Insufficiency, Chronic C0403447
Chronic Kidney Insufficiency
Definition (1)
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Renal Insufficiency C1565489
Children (1)
img Kidney Failure, Chronic C0022661
Ancestral Roots
RootRoot Plus OneDepthParent
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208876img Renal Insufficiency C1565489
img Male Urogenital Diseases C1720894img Urologic Diseases C00420755img Renal Insufficiency C1565489
Relationships (67)

Relation Types:
diso_​to_​anat : 5
diso_​to_​chem : 18
diso_​to_​diso : 41
diso_​to_​phen : 1
diso_​to_​phys : 2


Relationships:
none : 60
isa : 6
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO581img Complication Aspects C1171258
DISO_to_ANAT264img In Blood C0005768
DISO_to_DISO126img Cardiovascular Diseases C0007222
DISO_to_DISO101img Kidney Failure, Chronic C0022661
DISO_to_DISO84img Hypertension C0020538
DISO_to_DISO74img Anemia C0002871
DISO_to_ANAT59img Kidney C0022646
DISO_to_DISO56img Complication Aspects C1171258
DISO_to_DISO56img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_PHEN52img genetic aspects C0017399
DISO_to_CHEM47img Creatinine C0010294
DISO_to_CHEM45img Hematinics C0018928
DISO_to_DISO43img Acute kidney injury C2609414
DISO_to_DISO40img Diabetic Nephropathies C0011881
DISO_to_DISO40img Heart Failure C0018801
DISO_to_DISO39img Calcinosis C0006663
DISO_to_DISO39img Proteinuria C0033687
DISO_to_DISO37img Coronary Artery Disease C1956346
DISO_to_CHEM34img Erythropoietin C0014822
DISO_to_DISO32img Hyperparathyroidism, Secondary C0020503
DISO_to_DISO30img chemically induced C0007994
DISO_to_DISO29img Hypertension, Renal C0020544
DISO_to_DISO28img Metabolic Syndrome X C0524620
DISO_to_PHYS27img BIOL MARKER C0005516
DISO_to_DISO26img Albuminuria C0001925
Genes (53)

Species:
human : 53
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNPHP4261734nephronophthisis 4
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanCEP29080184centrosomal protein 290kDa
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanRETN56729resistin
img GENERIF, Score=1000, Pubmed Id: 16395259, UMLKSK CUI: C0403447
HumanAHI154806Abelson helper integration site 1
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanNAMPT10135nicotinamide phosphoribosyltransferase
img GENERIF, Score=1000, Pubmed Id: 17984105, UMLKSK CUI: C0403447
img GENERIF, Score=1000, Pubmed Id: 17261426, UMLKSK CUI: C0403447
HumanIQCB19657IQ motif containing B1
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=988, Pubmed Id: 12694320, UMLKSK CUI: C0403447
HumanSLC7A79056solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanPROZ8858protein Z, vitamin K-dependent plasma glycoprotein
img GENERIF, Score=1000, Pubmed Id: 18180611, UMLKSK CUI: C0403447
HumanFGF238074fibroblast growth factor 23
img GENERIF, Score=1000, Pubmed Id: 17567652, UMLKSK CUI: C0403447
img GENERIF, Score=1000, Pubmed Id: 14633152, UMLKSK CUI: C0403447
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
img GENERIF, Score=1000, Pubmed Id: 12687458, UMLKSK CUI: C0403447
HumanXDH7498xanthine dehydrogenase
img GENERIF, Score=1000, Pubmed Id: 18712049, UMLKSK CUI: C0403447
HumanWT17490Wilms tumor 1
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 11867956, UMLKSK CUI: C0403447
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17541791, UMLKSK CUI: C0403447
img GENERIF, Score=1000, Pubmed Id: 18547996, UMLKSK CUI: C0403447
HumanTLR47099toll-like receptor 4
img GENERIF, Score=694, Pubmed Id: 16738534, UMLKSK CUI: C0403447
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 15593053, UMLKSK CUI: C0403447
HumanHNF1B6928HNF1 homeobox B
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanSLC9A16548solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
img GENERIF, Score=756, Pubmed Id: 18480176, UMLKSK CUI: C0403447
HumanPLAUR5329plasminogen activator, urokinase receptor
img GENERIF, Score=756, Pubmed Id: 18508599, UMLKSK CUI: C0403447
HumanABCB15243ATP-binding cassette, sub-family B (MDR/TAP), member 1
img GENERIF, Score=1000, Pubmed Id: 17700595, UMLKSK CUI: C0403447
HumanPAX25076paired box 2
INFERRED, Score=800, UMLKSK CUI: C0403447
HumanTNFRSF11B4982tumor necrosis factor receptor superfamily, member 11b
img GENERIF, Score=1000, Pubmed Id: 18624938, UMLKSK CUI: C0403447
HumanSLC11A24891solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
img GENERIF, Score=756, Pubmed Id: 18667808, UMLKSK CUI: C0403447
HumanNPPB4879natriuretic peptide B
img GENERIF, Score=1000, Pubmed Id: 18632852, UMLKSK CUI: C0403447
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0403447Renal Insufficiency, Chronic0self