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Details
Link-It Detail - Disease - Gingival Overgrowth
Debug Stats
  • ### Total Build Time: 186 ms 42.070 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=1 ms Completed: 1 ms rowSize= 380 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=3 ms Completed: 3 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 553 bytes
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 1.403 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=21 ms Completed: 21 ms rowSize= 1.502 KB
  • CONCEPT_RELATIONSHIPS gt=74 ms Completed: 74 ms rowSize= 12.798 KB
  • CONCEPT_GENES gt=47 ms Completed: 47 ms rowSize= 23.764 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gingival Overgrowth C0376480
Definition (1)
Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Gingival Diseases C0017563
Children (3)
img Fibromatosis, Gingival C0016049
img Gingival Hyperplasia C0017566
img Gingival Hypertrophy C0017567
Ancestral Roots
RootRoot Plus OneDepthParent
img Stomatognathic Diseases C0038368img Mouth Diseases C00266365img Gingival Diseases C0017563
Relationships (28)

Relation Types:
diso_​to_​anat : 4
diso_​to_​chem : 10
diso_​to_​diso : 12
diso_​to_​phen : 2


Relationships:
none : 17
associated_​with : 1
isa : 8
location_​of : 1
permuted_​term_​of : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO90img chemically induced C0007994
DISO_to_DISO73img chemically induced C0007994
DISO_to_CHEM53img Cyclosporine C0010592
DISO_to_CHEM51img Immunosuppressive Agents C0021081
DISO_to_CHEM29img Immunosuppressive Agents C0021081
DISO_to_CHEM28img Cyclosporine C0010592
DISO_to_ANAT17img Gingiva C0017562
DISO_to_CHEM15img Calcium Channel Blockers C0006684
DISO_to_ANAT13img Gingiva C0017562
DISO_to_CHEM11img 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester C0028066
DISO_to_CHEM11img Nifedipine C0028066
DISO_to_PHEN11img genetic aspects C0017399
DISO_to_CHEM10img Calcium Channel Blockers C0006684
DISO_to_PHEN10img genetic aspects C0017399
DISO_to_CHEM8img 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester C0028066
DISO_to_ANAT7img Fibroblasts C0016030
DISO_to_CHEM7img Tacrolimus C0085149
DISO_to_ANATlocation_ofimg Gingiva C0017562
DISO_to_DISOisaimg Drug Induced Gingival Hyperplasia C0399439
DISO_to_DISOisaimg Epulides C0266919
DISO_to_DISOisaimg Gingival Hypertrophy C0017567
DISO_to_DISOpermuted_term_ofimg Gingival Overgrowth C0376480
DISO_to_DISOisaimg Gingival Pocket C0017571
DISO_to_DISOisaimg Gingival interdental papillary hyperplasia C1290660
DISO_to_DISOassociated_withimg Hypertrophy C0020564
Genes (26)

Species:
human : 26
Page Size
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SpeciesGeneGeneIdGene NameEvidence
HumanANTXR2118429anthrax toxin receptor 2
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanGINGF264644gingival fibromatosis, hereditary, 2
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanFAM20C56975family with sequence similarity 20, member C
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanSLC17A526503solute carrier family 17 (acidic sugar transporter), member 5
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanADAMTS29509ADAM metallopeptidase with thrombospondin type 1 motif, 2
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 18355347, UMLKSK CUI: C0376480
img GENERIF, Score=840, Pubmed Id: 12479636, UMLKSK CUI: C0376480
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=861, Pubmed Id: 18261581, UMLKSK CUI: C0376480
HumanSPARC6678secreted protein, acidic, cysteine-rich (osteonectin)
img GENERIF, Score=1000, Pubmed Id: 17970686, UMLKSK CUI: C0376480
HumanSOS16654son of sevenless homolog 1 (Drosophila)
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanMAPK105602mitogen-activated protein kinase 10
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanPLG5340plasminogen
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanABCB15243ATP-binding cassette, sub-family B (MDR/TAP), member 1
img GENERIF, Score=1000, Pubmed Id: 18702631, UMLKSK CUI: C0376480
img GENERIF, Score=1000, Pubmed Id: 15312098, UMLKSK CUI: C0376480
HumanROR24920receptor tyrosine kinase-like orphan receptor 2
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanMMP14312matrix metallopeptidase 1 (interstitial collagenase)
img GENERIF, Score=1000, Pubmed Id: 16945025, UMLKSK CUI: C0376480
HumanMGAT24247mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanMAN2B14125mannosidase, alpha, class 2B, member 1
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanITGA23673integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
img GAD, Score=1000, Pubmed Id: 16304451, UMLKSK CUI: C0376480
HumanINSR3643insulin receptor
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanIL153600interleukin 15
img GENERIF, Score=840, Pubmed Id: 12747456, UMLKSK CUI: C0376480
HumanHSPG23339heparan sulfate proteoglycan 2
img GENERIF, Score=840, Pubmed Id: 14974815, UMLKSK CUI: C0376480
HumanHGF3082hepatocyte growth factor (hepapoietin A; scatter factor)
img GENERIF, Score=861, Pubmed Id: 15250830, UMLKSK CUI: C0376480
HumanGLB12720galactosidase, beta 1
INFERRED, Score=800, UMLKSK CUI: C0376480
HumanFGF72252fibroblast growth factor 7
img GENERIF, Score=861, Pubmed Id: 15250830, UMLKSK CUI: C0376480
HumanEDN11906endothelin 1
img GENERIF, Score=840, Pubmed Id: 17274718, UMLKSK CUI: C0376480
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0376480Gingival Overgrowth0self