Human | ANTXR2 | 118429 | anthrax toxin receptor 2 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | GINGF2 | 64644 | gingival fibromatosis, hereditary, 2 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | FAM20C | 56975 | family with sequence similarity 20, member C | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | SLC17A5 | 26503 | solute carrier family 17 (acidic sugar transporter), member 5 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | ADAMTS2 | 9509 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | may contribute to a reduction of proteolytic activity of human gingival fibroblasts in Cyclosporin A-induced gingival overgrowth which favors the accumulation of extracellular matrix Lower level gene expression in patients treated with Cyclosporine A may be considered to be a risk factor for gingival overgrowth |
Human | TERT | 7015 | telomerase reverse transcriptase | There may be a relationship between cyclosporine-induced gingival overgrowth and telomerase activiy |
Human | SPARC | 6678 | secreted protein, acidic, cysteine-rich (osteonectin) | No association between SPARC gene polymorphism and gingival overgrowth was revealed in kidney transplant patients who were administered CsA |
Human | SOS1 | 6654 | son of sevenless homolog 1 (Drosophila) | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | MAPK10 | 5602 | mitogen-activated protein kinase 10 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | PLG | 5340 | plasminogen | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | ABCB1 | 5243 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | significant association between gingival overgrowth and the 3435TT genotype was confirmed by logistic regression analysis No association between gene polymorphism and gingival overgrowth was revealed in kidney transplant patients administered cyclosporine A as a principal immunosuppressive agent |
Human | ROR2 | 4920 | receptor tyrosine kinase-like orphan receptor 2 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | MMP2 | 4313 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | MMP1 | 4312 | matrix metallopeptidase 1 (interstitial collagenase) | No association between polymorphism and gingival enlargement was revealed in kidney transplant patients who were administered cyclosporin A as a principal immunosuppressive agent |
Human | MGAT2 | 4247 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | MAN2B1 | 4125 | mannosidase, alpha, class 2B, member 1 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | ITGA2 | 3673 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Title:{alpha}2 Integrin +807 Polymorphism in Drug-induced Gingival Overgrowth.|Association:Not Found|Conclusion:Not Found |
Human | INSR | 3643 | insulin receptor | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | IL15 | 3600 | interleukin 15 | may play a role in the pathogenesis of cyclosporin A-induced gingival overgrowth due to its interactions with cyclosporin A and its role in apoptosis and inflammation |
Human | HSPG2 | 3339 | heparan sulfate proteoglycan 2 | increased expression associated with Cyclosporin A-induced gingival overgrowth |
Human | HGF | 3082 | hepatocyte growth factor (hepapoietin A; scatter factor) | may have an important role in cyclosporin-induced gingival overgrowth |
Human | GLB1 | 2720 | galactosidase, beta 1 | INFERRED, Score=800, UMLKSK CUI: C0376480 |
Human | FGF7 | 2252 | fibroblast growth factor 7 | may have an important role in cyclosporin-induced gingival overgrowth |
Human | EDN1 | 1906 | endothelin 1 | cyclosporin A can modulate its expression in cyclosporin A-induced gingival overgrowth |