Human | HPC6 | 100188789 | Prostate cancer, susceptibility to | Early onset prostate cancer |
Human | CCR2 | 729230 | chemokine (C-C motif) receptor 2 | Results suggest that CCR2 may contribute to prostate cancer development |
Human | HPC5 | 619402 | prostate cancer, hereditary, 5 | Early onset prostate cancer |
Human | KLKP1 | 606293 | kallikrein pseudogene 1 | Transcription from KLKP1 is reduced as cells de-differentiate on the pathway to malignancy in prostate cancer |
Human | PCOTH | 542767 | | PCOTH is involved in growth and survival of prostate cancer cells thorough, in parts, the TAF-Ibeta pathway |
Human | TBC1D3B | 414059 | TBC1 domain family, member 3B | PRC17 is amplified in 15% of prostate cancers, it is highly overexpressed in approximately one-half of metastatic prostate tumors |
Human | HPC4 | 408260 | Prostate cancer, hereditary, 4 | Early onset prostate cancer |
Human | TDF | 403078 | | isolation if cDNA clone from a pituitary cDNA library; induced morphological and biochemical changes consistent with differentiation of human breast and prostate cancer cells; presence of TDF protein in sera suggests a role in endocrine metabolism |
Human | C5orf39 | 389289 | | annexin II and its receptor axis play a central role in prostate cancer metastasis, and prostate cancer utilizes the hematopoietic stem cell homing mechanisms to gain access to the niche |
Human | PRSS41 | 360226 | protease, serine, 41 | tessp1 protein was detectable in prostate cancer and in some ovarian cancer tissues, indicating tumor-related synthesis of tessp1 beyond testis tissue |
Human | HPCQTL19 | 347747 | Prostate cancer aggressiveness quantitative trait locus on chromosome 19 | Early onset prostate cancer |
Human | LOC285634 | 285634 | | transcriptional repression of DICE1 is caused by hypermethylation of the DICE1 promoter region in prostate cancer cells |
Human | KCNRG | 283518 | potassium channel regulator | the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene |
Human | STEAP2 | 261729 | STEAP family member 2, metalloreductase | Expression of STAMP2, a gene highly similar to STAMP1 (STEAP2), in prostate cancer cells significantly increases cell growth and colony formation suggesting that STAMP2 may have a role in cell proliferation |
Human | PI16 | 221476 | peptidase inhibitor 16 | a novel and independent prognostic markers following radical prostatectomy for prostate cancer |
Human | ALKBH3 | 221120 | alkB, alkylation repair homolog 3 (E. coli) | PCA-1 might be a novel diagnostic marker for prostate cancer, and increased PCA-1 expression might denote more aggressive variants of prostate cancer [PCA-1] |
Human | CRTC2 | 200186 | CREB regulated transcription coactivator 2 | TORC2 inhibition reduced proliferation and anchorage-independent growth of breast cancer and prostate cancer cell lines there are two parallel cell-survival pathways in prostate cancer cells: a strong Akt-independent, but rapamycin-sensitive pathway downstream of mTORC1, and an AR-dependent pathway downstream of mTORC2 and Akt, that is stimulated by mTORC1 inhibition |
Human | CADM4 | 199731 | cell adhesion molecule 4 | TSLL2 is expressed at the cell-cell attachment sites in the renal tubules, the transitional epithelia of the bladder, and the glandular epithelia of the prostate, and is a tumor-suppressor candidate in prostate cancer |
Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | ectopic expression of hPARM-1 in PC3 prostate cancer cells increased colony formation, suggesting a probable role in cell proliferation [PARM-1] |
Human | ADAMTS15 | 170689 | ADAM metallopeptidase with thrombospondin type 1 motif, 15 | negative effect of TGFbeta1 on ADAMTS-1, -5, -9, and -15 coupled with increases in their inhibitor, TIMP-3 may aid the accumulation of versican in the stromal compartment of the prostate in BPH and prostate cancer |
Human | OXER1 | 165140 | oxoeicosanoid (OXE) receptor 1 | 5-oxoER is critical for prostate cancer cell survival |
Human | TMPRSS6 | 164656 | transmembrane protease, serine 6 | Data show that genetic upregulation of matriptase-2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation |
Human | DAB2IP | 153090 | DAB2 interacting protein | Click here to display 3 evidence detail records. |
Human | CREB3L4 | 148327 | cAMP responsive element binding protein 3-like 4 | AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells |
Human | NRG4 | 145957 | neuregulin 4 | NRG4 overexpression is associated with advanced-stage prostate cancer |