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Details
Link-It Detail - Disease - Atypical chronic myeloid leukemia
Debug Stats
  • ### Total Build Time: 24 ms 28.270 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 364 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 443 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=15 ms Completed: 15 ms rowSize= 16.274 KB
  • CONCEPT_GENES gt=6 ms Completed: 6 ms rowSize= 9.970 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Atypical chronic myeloid leukemia C0349640
Definition (1)
A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene. The prognosis is usually poor. (WHO, 2001)
Relationships (43)

Relation Types:
diso_​to_​anat : 14
diso_​to_​diso : 22
diso_​to_​gene : 4
diso_​to_​phen : 3


Relationships:
associated_​with : 2
classifies : 1
gene_​associated_​with_​disease : 4
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 7
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​cytogenetic_​abnormality_​of_​disease : 2
is_​not_​molecular_​abnormality_​of_​disease : 3
may_​be_​abnormal_​cell_​of_​disease : 1
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 4
may_​be_​finding_​of_​disease : 3
may_​be_​molecular_​abnormality_​of_​disease : 1
replaces : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Bone Marrow C0005953
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Bone Marrow Stem Cell C1511246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Dysplastic Erythroid Precursor C1512102
DISO_to_ANATis_abnormal_cell_of_diseaseimg Dysplastic Megakaryocyte C1512106
DISO_to_ANATis_abnormal_cell_of_diseaseimg Dysplastic Neutrophil C1512107
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Haematopoietic tissue C0229619
DISO_to_ANATis_associated_anatomic_site_ofimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Myeloid Progenitor Cells C0596993
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Myeloid Cell C1514039
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Anemia C0002871
DISO_to_DISOis_not_molecular_abnormality_of_diseaseimg BCR-ABL1 Fusion Protein Expression C1516132
DISO_to_DISOmay_be_finding_of_diseaseimg Enlarged Liver C0019209
DISO_to_DISOmay_be_finding_of_diseaseimg Enlarged Spleen C0038002
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 13 C1517387
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 8 C1517422
DISO_to_DISOis_finding_of_diseaseimg Hypercellular bone marrow C1334068
DISO_to_DISOis_finding_of_diseaseimg Immature Granulocytes in Peripheral Blood Increased C1334152
DISO_to_DISOclassifiesimg Leukemia C0023418
DISO_to_DISOreplacesimg Leukemia, Myeloid C0023470
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Loss of Chromosome 12p C1517955
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanAFF427125AF4/FMR2 family, member 4
img NCI, Score=801, Pubmed Id: 15541471, UMLKSK CUI: C0349640
HumanTCF76932transcription factor 7 (T-cell specific, HMG-box)
img NCI, Score=801, Pubmed Id: 15541471, UMLKSK CUI: C0349640
HumanPDGFRB5159platelet-derived growth factor receptor, beta polypeptide
img NCI, Score=801, Pubmed Id: 15034867, UMLKSK CUI: C0349640
HumanPDGFRA5156platelet-derived growth factor receptor, alpha polypeptide
img NCI, Score=801, Pubmed Id: 12023981, UMLKSK CUI: C0349640
img NCI, Score=801, Pubmed Id: 12944919, UMLKSK CUI: C0349640
img NCI, Score=801, Pubmed Id: 15034867, UMLKSK CUI: C0349640
img NCI, Score=801, Pubmed Id: 12944919, UMLKSK CUI: C0349640
HumanPCM15108pericentriolar material 1
img NCI, Score=801, Pubmed Id: 16091753, UMLKSK CUI: C0349640
img GENERIF, Score=1000, Pubmed Id: 16091753, UMLKSK CUI: C0349640
HumanJAK23717Janus kinase 2
img GENERIF, Score=1000, Pubmed Id: 18555525, UMLKSK CUI: C0349640
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0349640Atypical chronic myeloid leukemia0self