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Details
Link-It Detail - Disease - Atypical Endometrial Hyperplasia
Debug Stats
  • ### Total Build Time: 34 ms 39.150 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 362 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 428 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=14 ms Completed: 14 ms rowSize= 7.292 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 29.851 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Atypical Endometrial Hyperplasia C0349579
Definition (1)
A benign form of endometrial hyperplasia with increased number of cells with atypia. The atypical cells are large and irregular and have an increased nuclear/cytoplasmic ratio. The risk of progression to endometrial carcinoma rises with the increasing degree of cell atypia.
Relationships (14)

Relation Types:
diso_​to_​anat : 4
diso_​to_​diso : 10


Relationships:
classifies : 1
is_​associated_​anatomic_​site_​of : 4
is_​finding_​of_​disease : 2
isa : 3
mapped_​to : 1
may_​be_​finding_​of_​disease : 2
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_associated_anatomic_site_ofimg Uterine cavity C0227844
DISO_to_ANATis_associated_anatomic_site_ofimg Uterus C0042149
DISO_to_DISOpermuted_term_ofimg Atypical Endometrial Hyperplasia C0349579
DISO_to_DISOisaimg Complex Endometrial Hyperplasia with Atypia C1333138
DISO_to_DISOmapped_toimg Complex atypical endometrial hyperplasia C1302454
DISO_to_DISOis_finding_of_diseaseimg Hyperplastic Tissue Present C1881084
DISO_to_DISOmay_be_finding_of_diseaseimg Infertility C0021359
DISO_to_DISOmay_be_finding_of_diseaseimg Obesity C0028754
DISO_to_DISOclassifiesimg Other and unspecified female genital disorders C0497480
DISO_to_DISOisaimg Simple Endometrial Hyperplasia with Atypia C1335966
DISO_to_DISOisaimg Simple atypical endometrial hyperplasia C1302435
DISO_to_DISOis_finding_of_diseaseimg atypia morphology C0741302
Genes (28)

Species:
human : 28
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanFLCN201163folliculin
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanMLH327030mutL homolog 3 (E. coli)
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanAXIN28313axin 2
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanEZR7430ezrin
img NCI, Score=801, Pubmed Id: 11880185, UMLKSK CUI: C0349579
HumanTP537157tumor protein p53
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanTLR47099toll-like receptor 4
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanTLR27097toll-like receptor 2
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanAURKA6790aurora kinase A
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanRBL25934retinoblastoma-like 2 (p130)
img NCI, Score=801, Pubmed Id: 11331952, UMLKSK CUI: C0349579
HumanPTPRJ5795protein tyrosine phosphatase, receptor type, J
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanPLA2G2A5320phospholipase A2, group IIA (platelets, synovial fluid)
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanPDGFRL5157platelet-derived growth factor receptor-like
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanODC14953ornithine decarboxylase 1
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanNRAS4893neuroblastoma RAS viral (v-ras) oncogene homolog
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 10631718, UMLKSK CUI: C0349579
img NCI, Score=801, Pubmed Id: 10631718, UMLKSK CUI: C0349579
HumanSMAD74092SMAD family member 7
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanKRAS3845Kirsten rat sarcoma viral oncogene homolog
img GENERIF, Score=660, Pubmed Id: 11746970, UMLKSK CUI: C0349579
HumanIGFBP13484insulin-like growth factor binding protein 1
img NCI, Score=801, Pubmed Id: 11928553, UMLKSK CUI: C0349579
HumanFLT42324fms-related tyrosine kinase 4
img NCI, Score=801, Pubmed Id: 12684405, UMLKSK CUI: C0349579
HumanFIGF2277c-fos induced growth factor (vascular endothelial growth factor D)
img NCI, Score=801, Pubmed Id: 12684405, UMLKSK CUI: C0349579
HumanEP3002033E1A binding protein p300
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanCCNE1898cyclin E1
img NCI, Score=801, Pubmed Id: 14648662, UMLKSK CUI: C0349579
HumanBUB1B701BUB1 mitotic checkpoint serine/threonine kinase B
img OMIM, Score=1000, UMLKSK CUI: C0349579
HumanBRAF673v-raf murine sarcoma viral oncogene homolog B
img NCI, Score=801, Pubmed Id: 16144912, UMLKSK CUI: C0349579
img NCI, Score=801, Pubmed Id: 16144912, UMLKSK CUI: C0349579
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0349579Atypical Endometrial Hyperplasia0self