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Details
Link-It Detail - Disease - Gestational Choriocarcinoma
Debug Stats
  • ### Total Build Time: 78 ms 18.512 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 645 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=56 ms Completed: 56 ms rowSize= 9.355 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 6.951 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Gestational Choriocarcinoma C0349557
Definition (1)
A rare, highly malignant, epithelial tumor that develops from a hydatidiform mole (50%), following abortion (25%), or during normal pregnancy (22%). Histologically, choriocarcinomas consist of invasive and anaplastic trophoblastic tissue composed of cytotrophoblastic and syncytiotrophoblastic cells, secretion of human chorionic gonadotropin, and abundant vascularity. Because of rapid growth and a high propensity for hemorrhage, this neoplasm often constitutes a medical emergency. --2004
Relationships (18)

Relation Types:
diso_​to_​anat : 9
diso_​to_​diso : 9


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
may_​be_​finding_​of_​disease : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Female Reproductive System C0700038
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Cytotrophoblastic Cell C1708870
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Intermediate Type Trophoblastic Cell C1881561
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Round Germ Cell with Glycogen-Rich Cytoplasm and Round Nucleus C1881590
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Syncytiotrophoblastic Giant Cell C1708920
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Trophoblastic Cell C1514116
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_DISOisaimg Fallopian Tube Gestational Choriocarcinoma C1333593
DISO_to_DISOisaimg Gestational Ovarian Choriocarcinoma C1517538
DISO_to_DISOisaimg Gestational Uterine Corpus Choriocarcinoma C1336904
DISO_to_DISOmay_be_finding_of_diseaseimg Hemorrhage C0019080
DISO_to_DISOis_finding_of_diseaseimg Human Chorionic Gonadotropin Positive Neoplastic Cells Present C1708390
DISO_to_DISOis_not_finding_of_diseaseimg Mixture of Germ Cell Neoplastic Components Present C1711227
DISO_to_DISOmay_be_finding_of_diseaseimg Necrotic changes (finding) C1334928
DISO_to_DISOisaimg Placental Choriocarcinoma C0855173
DISO_to_DISOis_finding_of_diseaseimg Pregnancy Complications C0032962
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanERAP151752endoplasmic reticulum aminopeptidase 1
img NCI, Score=801, Pubmed Id: 14691298, UMLKSK CUI: C0349557
HumanSDC26383syndecan 2
img NCI, Score=801, Pubmed Id: 2492529, UMLKSK CUI: C0349557
HumanLNPEP4012leucyl/cystinyl aminopeptidase
img NCI, Score=801, Pubmed Id: 2580800, UMLKSK CUI: C0349557
img NCI, Score=801, Pubmed Id: 14691298, UMLKSK CUI: C0349557
HumanENPEP2028glutamyl aminopeptidase (aminopeptidase A)
img NCI, Score=801, Pubmed Id: 10692253, UMLKSK CUI: C0349557
HumanAMBP259alpha-1-microglobulin/bikunin precursor
img NCI, Score=801, Pubmed Id: 8306525, UMLKSK CUI: C0349557
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0349557Gestational Choriocarcinoma0self