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GATACA
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Details
Link-It Detail - Disease - Pituitary carcinoma
Debug Stats
  • ### Total Build Time: 12 ms 17.489 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 562 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 15.285 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Disease (1)
Pituitary carcinoma C0346300
Definition (1)
A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly.
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanCOPS510987COP9 signalosome subunit 5
img NCI, Score=801, Pubmed Id: 12050228, UMLKSK CUI: C0346300
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 18026859, UMLKSK CUI: C0346300
HumanTOP2A7153topoisomerase (DNA) II alpha 170kDa
img GENERIF, Score=1000, Pubmed Id: 12429800, UMLKSK CUI: C0346300
HumanTHRB7068thyroid hormone receptor, beta
img GENERIF, Score=1000, Pubmed Id: 18683837, UMLKSK CUI: C0346300
HumanSYP6855synaptophysin
img NCI, Score=801, Pubmed Id: 9500236, UMLKSK CUI: C0346300
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 11519849, UMLKSK CUI: C0346300
HumanMEN14221multiple endocrine neoplasia I
img GAD, Score=1000, Pubmed Id: 11836268, UMLKSK CUI: C0346300
img GAD, Score=1000, Pubmed Id: 11369988, UMLKSK CUI: C0346300
HumanJUP3728junction plakoglobin
img NCI, Score=801, Pubmed Id: 11579678, UMLKSK CUI: C0346300
HumanID23398inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
img NCI, Score=801, Pubmed Id: 16943582, UMLKSK CUI: C0346300
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
img NCI, Score=801, Pubmed Id: 12792878, UMLKSK CUI: C0346300
HumanCCND1595cyclin D1
img GAD, Score=1000, Pubmed Id: 11698342, UMLKSK CUI: C0346300
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0346300Pituitary carcinoma0self