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Details
Link-It Detail - Disease - Dysgerminoma of Ovary
Debug Stats
  • ### Total Build Time: 25 ms 16.395 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 340 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 524 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=18 ms Completed: 18 ms rowSize= 11.551 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 2.774 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dysgerminoma of Ovary C0346185
Definition (1)
A malignant germ cell tumor arising from the ovary. Morphologically, it is identical to seminoma and consists of a monotonous population of germ cells with abundant pale cytoplasm and uniform nuclei. The stroma invariably contains chronic inflammatory cells, mostly T-lymphocytes. It responds to chemotherapy or radiotherapy and the prognosis relates to the tumor stage.
Relationships (23)

Relation Types:
diso_​to_​anat : 12
diso_​to_​diso : 11


Relationships:
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 5
may_​be_​finding_​of_​disease : 2
may_​be_​molecular_​abnormality_​of_​disease : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Female Reproductive System C0700038
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Germ Cells C0017471
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Layer C1708239
DISO_to_ANATis_associated_anatomic_site_ofimg Gonadal structure C0018067
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Germ Cell C1708878
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Primitive Germ Cell C1514071
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Germ Cell C1513971
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Sex Cord-Stromal Cell C1514083
DISO_to_ANATis_associated_anatomic_site_ofimg Ovary C0029939
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_DISOmay_be_finding_of_diseaseimg Abdominal Pain C0000737
DISO_to_DISOmay_be_finding_of_diseaseimg Abdominal mass C0000734
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg C-KIT Mutation C1511353
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg C-KIT Tyrosine Kinase Protein Overexpression C1511355
DISO_to_DISOisaimg Childhood Ovarian Dysgerminoma C1332988
DISO_to_DISOis_finding_of_diseaseimg Chronic Inflammatory Infiltrate C1333036
DISO_to_DISOis_finding_of_diseaseimg Fibrous Septa Present C1708055
DISO_to_DISOisaimg Stage I Ovarian Dysgerminoma C0854931
DISO_to_DISOisaimg Stage II Ovarian Dysgerminoma C0854932
DISO_to_DISOisaimg Stage III Ovarian Dysgerminoma C0854934
DISO_to_DISOisaimg Stage IV Ovarian Dysgerminoma C0854935
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanYBX251087Y box binding protein 2
img GENERIF, Score=983, Pubmed Id: 16479255, UMLKSK CUI: C0346185
HumanPTEN5728phosphatase and tensin homolog
img GENERIF, Score=1000, Pubmed Id: 18594467, UMLKSK CUI: C0346185
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0346185Dysgerminoma of Ovary0self