Human | LOC391533 | 391533 | | Increased soluble fms-like tyrosine kinase 1 is more likely to be present in women with severe preeclampsia, but it is not present in all women with preeclampsia |
Human | EBAG9 | 9166 | estrogen receptor binding site associated, antigen, 9 | The limited immune cells infiltration in decidua during severe pre-eclampsia is associated with increase in RCAS1 decidual level |
Human | TNF | 7124 | tumor necrosis factor | although the meta-analysis demonstrated a lack of an overall association between TNF-alpha G-308A polymorphism and preeclampsia, our results suggest a role of this SNP in the risk of severe IUGR-complicated preeclampsia |
Human | THBD | 7056 | thrombomodulin | Thrombomodulin (TM) expression in the stem villous vasculature and syncytiotrophoblast of the placenta is impaired in severe preeclampsia a significant correlation between thrombomodulin and severe preeclampsia and between population ethnicity and thrombomodulin level |
Human | SELP | 6403 | selectin P (granule membrane protein 140kDa, antigen CD62) | P-selectin Thr715Pro polymorphism is not associated with the risk of severe preeclampsia |
Human | SELE | 6401 | selectin E | E-selectin Serl28Arg polymorphism is not associated with the risk of severe preeclampsia |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | the G20210A prothrombin gene mutation and the PAI-1 5G/5G genotype have roles in early onset of severe preeclampsia |
Human | LGALS1 | 3956 | lectin, galactoside-binding, soluble, 1 | Placental galectin-1 mRNA expression was significantly higher in severe preeclampsia than in controls; Trophoblasts had the most intense galectin-1 immunostaining |
Human | LEPR | 3953 | leptin receptor | LEPR A223G polymorphism may individually modify the risk of severe pre-eclampsia |
Human | INHA | 3623 | inhibin, alpha | inhibin A may have a role in development of severe preeclampsia |
Human | IL16 | 3603 | interleukin 16 | IL-16 levels are significantly higher in severe preeclampsia (PE) than in mild PE and normal pregnant controls, indicating that increased IL-16 levels in PE are associated with the severity of the disease |
Human | SERPIND1 | 3053 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | HCII activity increases during pregnancy, and HCII levels are significantly decreased in women with severe pre-eclampsia |
Human | F5 | 2153 | coagulation factor V (proaccelerin, labile factor) | Screening 35 polymorphisms in 27 candidate genes showed that the R485K polymorphism in the coagulation factor V gene is associated with severe preeclampsia |
Human | F2 | 2147 | coagulation factor II (thrombin) | the G20210A prothrombin gene mutation and the PAI-1 5G/5G genotype have roles in early onset of severe preeclampsia |
Human | ESR1 | 2099 | estrogen receptor 1 | The homozygous T-A haplotype carriers of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms showed an increased risk of severe preeclampsia |
Human | ENG | 2022 | endoglin | Results suggest that soluble endoglin may act in concert with soluble Flt1 to induce severe preeclampsia |
Human | EDN1 | 1906 | endothelin 1 | serum ET-1 may have a role in severe brain edema in acute stroke patients treated with t-PA |
Human | CHRNA7 | 1139 | cholinergic receptor, nicotinic, alpha 7 (neuronal) | Placental expression of alpha7 nAChR is increased in severe preeclampsia placentas when compared with normal placentas |
Human | CACNA1A | 773 | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | The unique combination of a particularly slow inactivation of mutant S218L CaV2.1 channel during cortical spreading depression and a somewhat low threshold of channel activation might lead to delayed severe cerebral edema and coma after minor head trauma |
Human | AGT | 183 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | study shows that the M235T variant in the gene encoding angiotensinogen could be a risk factor in mild and severe pre-eclampsia |