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Details
Link-It Detail - Disease - Renal impairment
Debug Stats
  • ### Total Build Time: 18 ms 20.134 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 787 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=7 ms Completed: 7 ms rowSize= 3.805 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 14.018 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Renal impairment C0341697
Definition (1)
A condition in which the kidneys stop working and are not able to remove waste and extra water from the blood or keep body chemicals in balance. Acute or severe renal failure happens suddenly (for example, after an injury) and may be treated and cured. Chronic renal failure develops over many years, may be caused by conditions like high blood pressure or diabetes, and cannot be cured. Chronic renal failure may lead to total and long-lasting renal failure, called end-stage renal disease (ESRD). A person in ESRD needs dialysis (the process of cleaning the blood by passing it through a membrane or filter) or a kidney transplant.
Relationships (8)

Relation Types:
diso_​to_​diso : 8


Relationships:
associated_​with : 2
isa : 6
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISOisaimg Acute renal impairment C0403446
DISO_to_DISOisaimg Acute-on-chronic renal impairment C0585398
DISO_to_DISOisaimg Cardio Renal Syndrome C2242703
DISO_to_DISOisaimg Chronic Kidney Insufficiency C0403447
DISO_to_DISOassociated_withimg Gout due to impairment of renal function C0409909
DISO_to_DISOisaimg Kidney Failure C0035078
DISO_to_DISOassociated_withimg Raised calcium phosphate product C0342656
DISO_to_DISOisaimg Renal failure associated with renal vascular disease C1285418
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanHAMP57817hepcidin antimicrobial peptide
img GENERIF, Score=1000, Pubmed Id: 17112858, UMLKSK CUI: C0341697
HumanIKBKAP8518inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
img OMIM, Score=1000, UMLKSK CUI: C0341697
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17499233, UMLKSK CUI: C0341697
HumanLCN23934lipocalin 2
img GENERIF, Score=1000, Pubmed Id: 17901710, UMLKSK CUI: C0341697
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=1000, Pubmed Id: 18496509, UMLKSK CUI: C0341697
HumanHSD11B23291hydroxysteroid (11-beta) dehydrogenase 2
img GENERIF, Score=1000, Pubmed Id: 16061836, UMLKSK CUI: C0341697
HumanCST31471cystatin C
img GENERIF, Score=1000, Pubmed Id: 18418694, UMLKSK CUI: C0341697
img GENERIF, Score=875, Pubmed Id: 17537416, UMLKSK CUI: C0341697
img GENERIF, Score=901, Pubmed Id: 17826782, UMLKSK CUI: C0341697
img GENERIF, Score=905, Pubmed Id: 17210589, UMLKSK CUI: C0341697
HumanCRP1401C-reactive protein, pentraxin-related
img GENERIF, Score=901, Pubmed Id: 18075240, UMLKSK CUI: C0341697
img GENERIF, Score=1000, Pubmed Id: 17499233, UMLKSK CUI: C0341697
HumanAPOA4337apolipoprotein A-IV
img GENERIF, Score=1000, Pubmed Id: 16788210, UMLKSK CUI: C0341697
HumanALB213albumin
img GENERIF, Score=1000, Pubmed Id: 17499233, UMLKSK CUI: C0341697
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0341697Renal impairment0self