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Details
Link-It Detail - Disease - Epiretinal Membrane
Debug Stats
  • ### Total Build Time: 24 ms 16.058 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 933 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 189 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.492 KB
  • CONCEPT_RELATIONSHIPS gt=3 ms Completed: 3 ms rowSize= 8.671 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 2.743 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Epiretinal Membrane C0339543
Definition (1)
A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) retinal pigment epithelial cells. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the fovea centralis. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with retinal holes, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291)
Semantic Types (1)
Acquired Abnormality (T020)
Parents (1)
img Retinal Diseases C0035309
Ancestral Roots
RootRoot Plus OneDepthParent
img Eye Diseases C0015397img Retinal Diseases C00353093img Retinal Diseases C0035309
Relationships (21)

Relation Types:
diso_​to_​anat : 5
diso_​to_​chem : 4
diso_​to_​diso : 10
diso_​to_​phys : 2


Relationships:
none : 20
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO106img Retinal Perforations C0035321
DISO_to_DISO92img Retinal Perforations C0035321
DISO_to_CHEM66img Coloring Agents C1566391
DISO_to_CHEM61img Indocyanine Green C0021234
DISO_to_DISO42img Diabetic Retinopathy C0011884
DISO_to_CHEM39img Coloring Agents C1566391
DISO_to_ANAT37img Macula Lutea C0450295
DISO_to_ANAT37img Retina C0035298
DISO_to_ANAT35img Vitreous Body C0042905
DISO_to_PHYS35img Visual Acuity C0042812
DISO_to_ANAT31img Basement Membrane C0004799
DISO_to_DISO28img Complication Aspects C1171258
DISO_to_DISO27img Retinal Detachment C0035305
DISO_to_DISO26img Macular Edema C0271051
DISO_to_ANAT25img Vitreous Body C0042905
DISO_to_DISO25img Diabetic Retinopathy C0011884
DISO_to_CHEM21img Indocyanine Green C0021234
DISO_to_DISO21img COMPL POSTOP C0032787
DISO_to_DISO21img Macular Edema C0271051
DISO_to_PHYS21img Visual Acuity C0042812
DISO_to_DISOpermuted_term_ofimg ERM - Epiretinal membrane C0339543
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanTHBS17057thrombospondin 1
img GENERIF, Score=1000, Pubmed Id: 12658547, UMLKSK CUI: C0339543
HumanNFKB14790nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
img GENERIF, Score=1000, Pubmed Id: 12743697, UMLKSK CUI: C0339543
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0339543Epiretinal Membrane0self