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Details
Link-It Detail - Disease - Pilocytic Astrocytoma
Debug Stats
  • ### Total Build Time: 32 ms 35.422 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 340 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 490 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=10 ms Completed: 10 ms rowSize= 15.388 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 17.998 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Pilocytic Astrocytoma C0334583
Definition (1)
A WHO grade I, relatively circumscribed, slowly growing, often cystic astrocytoma occurring in children and young adults. Histologically it is characterized by a biphasic pattern with compacted bipolar cells associated with Rosenthal fibers and multipolar cells associated with microcysts and eosinophilic bodies/hyaline droplets. (WHO)
Relationships (41)

Relation Types:
diso_​to_​anat : 17
diso_​to_​diso : 23
diso_​to_​phen : 1


Relationships:
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 7
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 4
location_​of : 1
may_​be_​abnormal_​cell_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 4
may_​be_​finding_​of_​disease : 5
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Astrocytes C0004112
DISO_to_ANATlocation_ofimg Brain C0006104
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell, Neuroepithelial C1449624
DISO_to_ANATis_associated_anatomic_site_ofimg Central Nervous System C0927232
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Astrocyte C1513925
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Bipolar Astrocyte C1511177
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glial Cell C1513978
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Multipolar Astrocyte C1514032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Neuroepithelial Cell C1514048
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell C1514049
DISO_to_ANATmay_be_abnormal_cell_of_diseaseimg Neoplastic Oligodendrocyte-Like Cell C1514052
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Nerve Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System C1518293
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths C1518250
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Nervous System C0027763
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Neuroepithelial Tissue C1518281
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Neuroglia C0027836
DISO_to_DISOis_finding_of_diseaseimg Biphasic Pattern C1332555
DISO_to_DISOisaimg Cerebellar Pilocytic Astrocytoma C0349620
DISO_to_DISOisaimg Childhood Pilocytic Astrocytoma C1332995
DISO_to_DISOmay_be_finding_of_diseaseimg Eosinophilic Granular Bodies Present C1516900
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 19 C1517398
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 22 C1517407
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 7 C1517417
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 8 C1517422
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanOLIG1116448oligodendrocyte transcription factor 1
img GENERIF, Score=1000, Pubmed Id: 17690840, UMLKSK CUI: C0334583
HumanHIPK228996homeodomain interacting protein kinase 2
img GENERIF, Score=1000, Pubmed Id: 18408760, UMLKSK CUI: C0334583
HumanTUBB310381tubulin, beta 3 class III
img GENERIF, Score=1000, Pubmed Id: 17543088, UMLKSK CUI: C0334583
HumanOLIG210215oligodendrocyte lineage transcription factor 2
img GENERIF, Score=1000, Pubmed Id: 17690840, UMLKSK CUI: C0334583
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 18383819, UMLKSK CUI: C0334583
HumanSOX106663SRY (sex determining region Y)-box 10
img GENERIF, Score=1000, Pubmed Id: 16896310, UMLKSK CUI: C0334583
HumanPDGFRA5156platelet-derived growth factor receptor, alpha polypeptide
img GENERIF, Score=1000, Pubmed Id: 17690840, UMLKSK CUI: C0334583
HumanNRAS4893neuroblastoma RAS viral (v-ras) oncogene homolog
img GENERIF, Score=1000, Pubmed Id: 17712732, UMLKSK CUI: C0334583
HumanNF14763neurofibromin 1
img GENERIF, Score=901, Pubmed Id: 12387455, UMLKSK CUI: C0334583
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
img OMIM, Score=1000, UMLKSK CUI: C0334583
HumanMBP4155myelin basic protein
img GENERIF, Score=1000, Pubmed Id: 17690840, UMLKSK CUI: C0334583
HumanMATN24147matrilin 2
img GENERIF, Score=861, Pubmed Id: 16401863, UMLKSK CUI: C0334583
HumanKRAS3845Kirsten rat sarcoma viral oncogene homolog
img GENERIF, Score=1000, Pubmed Id: 17712732, UMLKSK CUI: C0334583
HumanHRAS3265Harvey rat sarcoma viral oncogene homolog
img GENERIF, Score=1000, Pubmed Id: 17712732, UMLKSK CUI: C0334583
HumanERBB32065v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
img GENERIF, Score=1000, Pubmed Id: 16896310, UMLKSK CUI: C0334583
HumanBRAF673v-raf murine sarcoma viral oncogene homolog B
img GENERIF, Score=901, Pubmed Id: 18716556, UMLKSK CUI: C0334583
HumanAQP4361aquaporin 4
img GENERIF, Score=1000, Pubmed Id: 17335082, UMLKSK CUI: C0334583
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0334583Pilocytic Astrocytoma0self