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Details
Link-It Detail - Disease - Adrenal medullary paraganglioma, malignant
Debug Stats
  • ### Total Build Time: 207 ms 29.932 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 382 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 467 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=179 ms Completed: 179 ms rowSize= 14.682 KB
  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 13.175 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.176 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adrenal medullary paraganglioma, malignant C0334419
Definition (1)
A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis include lymph nodes, bones, liver, and lung. Morphologic features associated with malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular invasion, tumor cell necrosis, and high mitotic activity.
Relationships (41)

Relation Types:
diso_​to_​anat : 26
diso_​to_​diso : 15


Relationships:
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 9
is_​associated_​anatomic_​site_​of : 4
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​normal_​tissue_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 5
isa : 2
may_​be_​finding_​of_​disease : 10
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Abdominal Cavity C0230168
DISO_to_ANATis_not_normal_tissue_origin_of_diseaseimg Adrenal Cortex C0001613
DISO_to_ANATis_associated_anatomic_site_ofimg Adrenal Glands C0001625
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Adrenal Medulla C0001629
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Autonomic Nervous System C0004388
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Autonomic nervous system C0004388
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell, Chromaffin C0376604
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Chromaffin Cells C0376604
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Endocrine System C0014136
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Chromaffin Cell C1708866
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Endocrine Cell C1518172
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Neuroendocrine Cell C1518216
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Chromaffin Cell C1709168
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Endocrine Cell C1513951
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Neuroendocrine Cell C1514044
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_associated_anatomic_site_ofimg Nervous System C0027763
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Neural Crest-Derived Cell C1709215
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Peripheral Nerves C0031119
DISO_to_ANATis_associated_anatomic_site_ofimg Retroperitoneal Space C0035359
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanSCG27857secretogranin II
img GENERIF, Score=1000, Pubmed Id: 12788858, UMLKSK CUI: C0334419
img NCI, Score=801, Pubmed Id: 15601318, UMLKSK CUI: C0334419
img NCI, Score=801, Pubmed Id: 15601318, UMLKSK CUI: C0334419
img NCI, Score=801, Pubmed Id: 17102121, UMLKSK CUI: C0334419
img NCI, Score=801, Pubmed Id: 17102121, UMLKSK CUI: C0334419
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=694, Pubmed Id: 15004408, UMLKSK CUI: C0334419
HumanSLC18A16570solute carrier family 18 (vesicular monoamine transporter), member 1
img NCI, Score=801, Pubmed Id: 17102116, UMLKSK CUI: C0334419
HumanSDHB6390succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
img GAD, Score=1000, Pubmed Id: 14500403, UMLKSK CUI: C0334419
img GENERIF, Score=1000, Pubmed Id: 17652212, UMLKSK CUI: C0334419
HumanEPAS12034endothelial PAS domain protein 1
img NCI, Score=801, Pubmed Id: 12368197, UMLKSK CUI: C0334419
HumanCHGB1114chromogranin B (secretogranin 1)
img NCI, Score=801, Pubmed Id: 2847571, UMLKSK CUI: C0334419
HumanCDH21000cadherin 2, type 1, N-cadherin (neuronal)
img NCI, Score=801, Pubmed Id: 12165657, UMLKSK CUI: C0334419
HumanBIRC5332baculoviral IAP repeat containing 5
img GENERIF, Score=1000, Pubmed Id: 11888845, UMLKSK CUI: C0334419
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0334419Adrenal medullary paraganglioma, malignant0self