Logo arc image image
GATACA
  • Pin/Unpin Search
  • Pin/Unpin Details
Status:
Global Actions
Concepts: 0 (0)   Selected: 0 (0
Clear All Selections
 
Search
Text Search Results
Text Search Query:
none
Text Search Options:
none

Guided Help

Text Search Results
GraphTree Minimize or Maximize this Category
 Disease: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Anatomy: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Gene: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Jax Mouse Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Human Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Biological Processes: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Cellular Component: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Molecular Function: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Pathway: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Drug: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Genomic Expression Atlas --
      Microarray Datasets: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 PubMed: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 CoExpression Atlas: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 CoExpression: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Interactions: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Details
Link-It Detail - Disease - CA - Squamous cell carcinoma of vulva
Debug Stats
  • ### Total Build Time: 6 ms 31.817 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 372 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 999 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 13.905 KB
  • CONCEPT_GENES gt=6 ms Completed: 6 ms rowSize= 15.332 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
CA - Squamous cell carcinoma of vulva C0280856
Definition (1)
An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumor giant cells. Risk factors for recurrence include advanced stage, tumor diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumor. (WHO, 2003)
Relationships (28)

Relation Types:
diso_​to_​anat : 16
diso_​to_​diso : 12


Relationships:
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 3
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 3
is_​not_​finding_​of_​disease : 1
isa : 9
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_associated_anatomic_site_ofimg Female Reproductive System C0700038
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Squamous Cell C0221910
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Squamous Epithelium C0221909
DISO_to_ANATis_associated_anatomic_site_ofimg Vulva C0042993
DISO_to_DISOisaimg Bartholin Gland Squamous Cell Carcinoma C1511052
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOisaimg HPV-Related Vulvar Squamous Cell Carcinoma C1334059
DISO_to_DISOis_not_finding_of_diseaseimg Mixed Neoplastic Glandular and Squamous Cell Population C1881876
DISO_to_DISOisaimg Squamous cell carcinoma of vulva due to lichen sclerosus C1275178
DISO_to_DISOisaimg Verrucous Carcinoma of Vulva C1336983
DISO_to_DISOisaimg Vulvar Basaloid Carcinoma C2211850
DISO_to_DISOisaimg Vulvar Keratinizing Squamous Cell Carcinoma C2109334
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanHIST3H2BB128312histone cluster 3, H2bb
img NCI, Score=801, Pubmed Id: 12722370, UMLKSK CUI: C0280856
HumanCHEK211200checkpoint kinase 2
img NCI, Score=801, Pubmed Id: 11875739, UMLKSK CUI: C0280856
img NCI, Score=801, Pubmed Id: 11875739, UMLKSK CUI: C0280856
img GENERIF, Score=965, Pubmed Id: 11875739, UMLKSK CUI: C0280856
HumanRBL25934retinoblastoma-like 2 (p130)
img NCI, Score=801, Pubmed Id: 11172288, UMLKSK CUI: C0280856
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 15568401, UMLKSK CUI: C0280856
img NCI, Score=801, Pubmed Id: 15568401, UMLKSK CUI: C0280856
img NCI, Score=801, Pubmed Id: 15568401, UMLKSK CUI: C0280856
HumanMMP134322matrix metallopeptidase 13 (collagenase 3)
img NCI, Score=801, Pubmed Id: 10027405, UMLKSK CUI: C0280856
HumanMMP124321matrix metallopeptidase 12 (macrophage elastase)
img NCI, Score=801, Pubmed Id: 12237887, UMLKSK CUI: C0280856
HumanMDK4192midkine (neurite growth-promoting factor 2)
img NCI, Score=801, Pubmed Id: 12901536, UMLKSK CUI: C0280856
HumanIVL3713involucrin
img NCI, Score=801, Pubmed Id: 8625158, UMLKSK CUI: C0280856
HumanIL1A3552interleukin 1, alpha
img NCI, Score=801, Pubmed Id: 14984963, UMLKSK CUI: C0280856
HumanSFN2810stratifin
img GENERIF, Score=988, Pubmed Id: 18950492, UMLKSK CUI: C0280856
HumanEDNRB1910endothelin receptor type B
img GENERIF, Score=1000, Pubmed Id: 17611649, UMLKSK CUI: C0280856
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0280856CA - Squamous cell carcinoma of vulva0self