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Details
Link-It Detail - Disease - Endodermal Sinus Neoplasm of Testis
Debug Stats
  • ### Total Build Time: 42 ms 19.026 KB
  • CONCEPT_NAME gt=28 ms Completed: 28 ms rowSize= 368 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 631 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=9 ms Completed: 9 ms rowSize= 15.240 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 1.571 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.169 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Endodermal Sinus Neoplasm of Testis C0279708
Definition (1)
A non-seminomatous malignant germ cell tumor arising from the testis. It affects infants, young children, and postpubertal males. It is the most frequently seen testicular neoplasm during childhood. The vast majority of patients present with an asymptomatic scrotal mass. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). It metastasizes to distant anatomic sites. Prognostic factors relate to the clinical stage and the degree of AFP elevation.
Relationships (39)

Relation Types:
diso_​to_​anat : 12
diso_​to_​diso : 27


Relationships:
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 2
is_​cytogenetic_​abnormality_​of_​disease : 2
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 13
may_​be_​associated_​disease_​of_​disease : 3
may_​be_​cytogenetic_​abnormality_​of_​disease : 2
may_​be_​finding_​of_​disease : 4
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Germ Cells C0017471
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Germinal Layer C1708239
DISO_to_ANATis_associated_anatomic_site_ofimg Gonadal structure C0018067
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Male Reproductive System C1963704
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Germ Cell C1708878
DISO_to_ANATis_abnormal_cell_of_diseaseimg Malignant Primitive Germ Cell C1514071
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Germ Cell C1513971
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Sex Cord-Stromal Cell C1514083
DISO_to_ANATis_associated_anatomic_site_ofimg Reproductive system C1261210
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Testis C0039597
DISO_to_DISOmay_be_finding_of_diseaseimg ALPHA-FETOPROTEIN INCREASED C0235971
DISO_to_DISOis_cytogenetic_abnormality_of_diseaseimg Alteration of chromosome number C0002938
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Cryptorchidism C0010417
DISO_to_DISOmay_be_finding_of_diseaseimg Cytoplasmic Hyaline Globules Present C1707603
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg Gain of Chromosome 12p C1517383
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Gonocytoma In Situ C1515286
DISO_to_DISOis_cytogenetic_abnormality_of_diseaseimg Hypotriploidy C1512572
DISO_to_DISOis_finding_of_diseaseimg Mitotic Activity C1334779
DISO_to_DISOis_not_finding_of_diseaseimg Mixture of Germ Cell Neoplastic Components Present C1711227
DISO_to_DISOmay_be_finding_of_diseaseimg Painless testicular mass C1848888
DISO_to_DISOmay_be_associated_disease_of_diseaseimg Penile hypospadias C1691215
DISO_to_DISOmay_be_finding_of_diseaseimg Schiller-Duval Body C1710022
DISO_to_DISOis_not_finding_of_diseaseimg Seminomatous Component Present C1882999
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanRUNX3864runt-related transcription factor 3
img GENERIF, Score=983, Pubmed Id: 12875960, UMLKSK CUI: C0279708
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0279708Endodermal Sinus Neoplasm of Testis0self