Logo arc image image
GATACA
  • Pin/Unpin Search
  • Pin/Unpin Details
Status:
Global Actions
Concepts: 0 (0)   Selected: 0 (0
Clear All Selections
 
Search
Text Search Results
Text Search Query:
none
Text Search Options:
none

Guided Help

Text Search Results
GraphTree Minimize or Maximize this Category
 Disease: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Anatomy: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Gene: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Jax Mouse Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Human Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Biological Processes: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Cellular Component: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Molecular Function: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Pathway: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Drug: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Genomic Expression Atlas --
      Microarray Datasets: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 PubMed: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 CoExpression Atlas: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 CoExpression: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Interactions: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Details
Link-It Detail - Disease - ADENOCARCINOMA OF ESOPHAGUS
Debug Stats
  • ### Total Build Time: 180 ms 53.132 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 637 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=122 ms Completed: 122 ms rowSize= 15.536 KB
  • CONCEPT_GENES gt=44 ms Completed: 44 ms rowSize= 35.398 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
ADENOCARCINOMA OF ESOPHAGUS C0279628
Definition (1)
A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.
Relationships (47)

Relation Types:
diso_​to_​anat : 15
diso_​to_​chem : 1
diso_​to_​diso : 29
diso_​to_​gene : 2


Relationships:
gene_​associated_​with_​disease : 2
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 6
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 4
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 11
may_​be_​cytogenetic_​abnormality_​of_​disease : 6
may_​be_​molecular_​abnormality_​of_​disease : 7
related_​to : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_abnormal_cell_of_diseaseimg Adenocarcinoma Cell C1510779
DISO_to_ANATis_abnormal_cell_of_diseaseimg Cancer Cell C0334227
DISO_to_ANATis_abnormal_cell_of_diseaseimg Carcinoma Cell C1518174
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Digestive System C0012240
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Epithelial Cells C0014597
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelial Tissue C0014609
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Epithelium of esophagus C1179544
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Esophagus C0014876
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Squamous Cell C1518245
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Malignant Stromal Cell C1518246
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Epithelial Cell C1513959
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Glandular Cell C1513973
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Smooth Muscle Cell C1514098
DISO_to_ANATis_not_abnormal_cell_of_diseaseimg Neoplastic Squamous Cell C1514101
DISO_to_CHEMgene_product_malfunction_associated_with_diseaseimg Cathepsin B C0699919
DISO_to_DISOmay_be_cytogenetic_abnormality_of_diseaseimg 5q Deletion C1521461
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg APC Gene Inactivation C1515857
DISO_to_DISOisaimg Adenocarcinoma of lower esophagus C3164003
DISO_to_DISOrelated_toimg Barrett Esophagus C0004763
DISO_to_DISOisaimg Barrett's Adenocarcinoma C1332460
DISO_to_DISOis_not_finding_of_diseaseimg Benign Cellular Infiltrate C1332480
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg CDKN2A Gene Inactivation C1511430
DISO_to_DISOis_finding_of_diseaseimg Carcinomatous Component Present C1707292
DISO_to_DISOmay_be_molecular_abnormality_of_diseaseimg EGFR Gene Activation C1512116
Genes (81)

Species:
human : 81
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNOX579400NADPH oxidase, EF-hand calcium binding domain 5
img GENERIF, Score=734, Pubmed Id: 17947454, UMLKSK CUI: C0279628
HumanAKR1B1057016aldo-keto reductase family 1, member B10 (aldose reductase)
img GENERIF, Score=1000, Pubmed Id: 18396902, UMLKSK CUI: C0279628
HumanRPRM56475reprimo, TP53 dependent G2 arrest mediator candidate
img NCI, Score=801, Pubmed Id: 15700311, UMLKSK CUI: C0279628
HumanTNFRSF12A51330tumor necrosis factor receptor superfamily, member 12A
img GENERIF, Score=1000, Pubmed Id: 17594693, UMLKSK CUI: C0279628
HumanADIPOR151094adiponectin receptor 1
img GENERIF, Score=660, Pubmed Id: 18313838, UMLKSK CUI: C0279628
HumanNUDT611162nudix (nucleoside diphosphate linked moiety X)-type motif 6
img GENERIF, Score=1000, Pubmed Id: 17569023, UMLKSK CUI: C0279628
HumanUBE2C11065ubiquitin-conjugating enzyme E2C
img GENERIF, Score=673, Pubmed Id: 17217624, UMLKSK CUI: C0279628
HumanNR1H49971nuclear receptor subfamily 1, group H, member 4
img GENERIF, Score=1000, Pubmed Id: 17054793, UMLKSK CUI: C0279628
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=660, Pubmed Id: 18313838, UMLKSK CUI: C0279628
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
img NCI, Score=801, Pubmed Id: 12957466, UMLKSK CUI: C0279628
HumanTNFRSF6B8771tumor necrosis factor receptor superfamily, member 6b, decoy
img NCI, Score=801, Pubmed Id: 10655513, UMLKSK CUI: C0279628
img NCI, Score=801, Pubmed Id: 16040301, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 16040301, UMLKSK CUI: C0279628
HumanTFPI27980tissue factor pathway inhibitor 2
img NCI, Score=801, Pubmed Id: 15735751, UMLKSK CUI: C0279628
HumanXRCC17515X-ray repair complementing defective repair in Chinese hamster cells 1
img GENERIF, Score=734, Pubmed Id: 17264068, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 18349297, UMLKSK CUI: C0279628
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=734, Pubmed Id: 18780893, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 16984727, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 16702519, UMLKSK CUI: C0279628
HumanTSC17248tuberous sclerosis 1
img GENERIF, Score=913, Pubmed Id: 18413730, UMLKSK CUI: C0279628
HumanHSP90B17184heat shock protein 90kDa beta (Grp94), member 1
img GENERIF, Score=983, Pubmed Id: 18331622, UMLKSK CUI: C0279628
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 15680394, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 17982662, UMLKSK CUI: C0279628
HumanTIMP37078TIMP metallopeptidase inhibitor 3
img NCI, Score=801, Pubmed Id: 11487270, UMLKSK CUI: C0279628
img GENERIF, Score=1000, Pubmed Id: 15688381, UMLKSK CUI: C0279628
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 11487270, UMLKSK CUI: C0279628
HumanTGFBI7045transforming growth factor, beta-induced, 68kDa
img NCI, Score=801, Pubmed Id: 12680208, UMLKSK CUI: C0279628
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 16921482, UMLKSK CUI: C0279628
HumanSPARC6678secreted protein, acidic, cysteine-rich (osteonectin)
img NCI, Score=801, Pubmed Id: 14562024, UMLKSK CUI: C0279628
HumanSOD26648superoxide dismutase 2, mitochondrial
img GENERIF, Score=1000, Pubmed Id: 17277236, UMLKSK CUI: C0279628
HumanSLC1A46509solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
img NCI, Score=801, Pubmed Id: 11268453, UMLKSK CUI: C0279628
HumanSFRP16422secreted frizzled-related protein 1
img GENERIF, Score=983, Pubmed Id: 16407829, UMLKSK CUI: C0279628
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0279628ADENOCARCINOMA OF ESOPHAGUS0self