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Details
Link-It Detail - Disease - Cancer of Head and Neck
Debug Stats
  • ### Total Build Time: 126 ms 42.021 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 344 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.383 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=7 ms Completed: 7 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=80 ms Completed: 80 ms rowSize= 38.971 KB
  • CONCEPT_XREFS gt=25 ms Completed: 25 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cancer of Head and Neck C0278996
Definition (1)

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes in the neck. Most begin in the moist tissues that line the mouth, nose and throat. Symptoms include

  • A lump or sore that does not heal
  • A sore throat that does not go away
  • Trouble swallowing
  • A change or hoarseness in the voice

Using tobacco or alcohol increases your risk. In fact, 85 percent of head and neck cancers are linked to tobacco use, including smoking and smokeless tobacco. If found early, these cancers are often curable. Treatments may include surgery, radiation therapy, chemotherapy or a combination. Treatments can affect eating, speaking or even breathing, so patients may need rehabilitation.

NIH: National Cancer Institute

Genes (134)

Species:
human : 133
mouse : 1
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseLY6D8581lymphocyte antigen 6 complex, locus D
img NCI, Score=801, Pubmed Id: 9083342, UMLKSK CUI: C0278996
HumanCSMD2114784CUB and Sushi multiple domains 2
img NCI, Score=801, Pubmed Id: 12906867, UMLKSK CUI: C0278996
HumanABCC1089845ATP-binding cassette, sub-family C (CFTR/MRP), member 10
img GENERIF, Score=771, Pubmed Id: 17203221, UMLKSK CUI: C0278996
HumanCYSLTR257105cysteinyl leukotriene receptor 2
img NCI, Score=801, Pubmed Id: 12414665, UMLKSK CUI: C0278996
HumanCHFR55743checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
img NCI, Score=801, Pubmed Id: 12810945, UMLKSK CUI: C0278996
HumanING354556inhibitor of growth family, member 3
img NCI, Score=801, Pubmed Id: 15935570, UMLKSK CUI: C0278996
img GENERIF, Score=904, Pubmed Id: 12080476, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 12080476, UMLKSK CUI: C0278996
img GENERIF, Score=1000, Pubmed Id: 18081876, UMLKSK CUI: C0278996
HumanTLR751284toll-like receptor 7
img GENERIF, Score=1000, Pubmed Id: 18949362, UMLKSK CUI: C0278996
HumanING451147inhibitor of growth family, member 4
img GENERIF, Score=1000, Pubmed Id: 15935570, UMLKSK CUI: C0278996
HumanCTAG230848cancer/testis antigen 2
img NCI, Score=801, Pubmed Id: 9626360, UMLKSK CUI: C0278996
HumanBBC327113BCL2 binding component 3
img NCI, Score=801, Pubmed Id: 12963126, UMLKSK CUI: C0278996
HumanLY9623643lymphocyte antigen 96
img NCI, Score=801, Pubmed Id: 15289356, UMLKSK CUI: C0278996
HumanSTAB123166stabilin 1
img NCI, Score=801, Pubmed Id: 12907648, UMLKSK CUI: C0278996
HumanKLRK122914killer cell lectin-like receptor subfamily K, member 1
img NCI, Score=801, Pubmed Id: 12124336, UMLKSK CUI: C0278996
HumanOGFR11054opioid growth factor receptor
img GENERIF, Score=966, Pubmed Id: 16685459, UMLKSK CUI: C0278996
HumanCOPS510987COP9 signalosome subunit 5
img NCI, Score=801, Pubmed Id: 16077910, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 16077910, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 16077910, UMLKSK CUI: C0278996
HumanLYVE110894lymphatic vessel endothelial hyaluronan receptor 1
img NCI, Score=801, Pubmed Id: 11888898, UMLKSK CUI: C0278996
HumanGJB610804gap junction protein, beta 6, 30kDa
img GENERIF, Score=1000, Pubmed Id: 17695503, UMLKSK CUI: C0278996
HumanPOSTN10631periostin, osteoblast specific factor
img NCI, Score=801, Pubmed Id: 16849536, UMLKSK CUI: C0278996
HumanCCNA18900cyclin A1
img NCI, Score=801, Pubmed Id: 15342377, UMLKSK CUI: C0278996
HumanTNFRSF10B8795tumor necrosis factor receptor superfamily, member 10b
img NCI, Score=801, Pubmed Id: 12175536, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 10762627, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 9721851, UMLKSK CUI: C0278996
HumanABCC38714ATP-binding cassette, sub-family C (CFTR/MRP), member 3
img NCI, Score=801, Pubmed Id: 9813153, UMLKSK CUI: C0278996
HumanLY6D8581lymphocyte antigen 6 complex, locus D
Click here to display 22 evidence detail records.
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
img NCI, Score=801, Pubmed Id: 16472552, UMLKSK CUI: C0278996
HumanXRCC37517X-ray repair complementing defective repair in Chinese hamster cells 3
img GAD, Score=1000, Pubmed Id: 16030112, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 16030112, UMLKSK CUI: C0278996
img NCI, Score=801, Pubmed Id: 16030112, UMLKSK CUI: C0278996
HumanXRCC17515X-ray repair complementing defective repair in Chinese hamster cells 1
img GAD, Score=1000, Pubmed Id: 11981277, UMLKSK CUI: C0278996
img GAD, Score=1000, Pubmed Id: 16030112, UMLKSK CUI: C0278996
img GAD, Score=1000, Pubmed Id: 15252855, UMLKSK CUI: C0278996
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0278996Cancer of Head and Neck0self