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Details
Link-It Detail - Disease - Exocrine Pancreatic Insufficiency
Debug Stats
  • ### Total Build Time: 22 ms 23.756 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 364 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 451 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.511 KB
  • CONCEPT_RELATIONSHIPS gt=9 ms Completed: 9 ms rowSize= 10.292 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 9.229 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Exocrine Pancreatic Insufficiency C0267963
Definition (1)
Inability of the exocrine pancreas to produce and secrete an adequate amount of digestive enzymes into the small intestine. Patients present with symptoms of malabsorption syndrome, abdominal discomfort, and bloating. Causes include chronic pancreatitis, cystic fibrosis, and autoimmune disorders.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Pancreatic Diseases C0030286
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Pancreatic Diseases C00302863img Pancreatic Diseases C0030286
Relationships (24)

Relation Types:
diso_​to_​anat : 8
diso_​to_​chem : 5
diso_​to_​diso : 9
diso_​to_​phen : 2


Relationships:
none : 20
is_​associated_​anatomic_​site_​of : 1
location_​of : 1
mapped_​to : 1
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO40img Cystic Fibrosis C0010674
DISO_to_PHEN36img genetic aspects C0017399
DISO_to_DISO33img Complication Aspects C1171258
DISO_to_DISO31img Complication Aspects C1171258
DISO_to_PHEN31img genetic aspects C0017399
DISO_to_CHEM29img Pancreatic Elastase C0030306
DISO_to_ANAT27img Feces C0015733
DISO_to_DISO25img Bone Marrow Diseases C0005956
DISO_to_CHEM21img Pancreatic Elastase C0030306
DISO_to_ANAT20img Pancreas C0030274
DISO_to_CHEM20img 84-85 GASTROINTESTINAL DRUGS C0017173
DISO_to_DISO20img Pancreatitis, Chronic C0149521
DISO_to_CHEM18img Pancrelipase C0770343
DISO_to_ANAT17img Feces C0015733
DISO_to_ANAT17img Pancreas C0030274
DISO_to_DISO16img Lipomatosis C0023801
DISO_to_ANAT12img In Blood C0005768
DISO_to_DISO12img Pancreatitis C0030305
DISO_to_ANAT11img Exocrine pancreas C0553695
DISO_to_CHEM11img Proteins C0033684
DISO_to_ANATis_associated_anatomic_site_ofimg Digestive System C0012240
DISO_to_ANATlocation_ofimg Pancreas C0030274
DISO_to_DISOpermuted_term_ofimg Exocrine Pancreatic Insufficiency C0267963
DISO_to_DISOmapped_toimg Shwachman syndrome C0272170
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanUBR1197131ubiquitin protein ligase E3 component n-recognin 1
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanSBDS51119Shwachman-Bodian-Diamond syndrome
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanCTRC11330chymotrypsin C (caldecrin)
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanTGFB17040transforming growth factor, beta 1
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanSPINK16690serine peptidase inhibitor, Kazal type 1
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanPRSS15644protease, serine, 1 (trypsin 1)
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanPDX13651pancreatic and duodenal homeobox 1
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanCELA11990chymotrypsin-like elastase family, member 1
img GENERIF, Score=1000, Pubmed Id: 18362841, UMLKSK CUI: C0267963
HumanCTNS1497cystinosin, lysosomal cystine transporter
img OMIM, Score=1000, UMLKSK CUI: C0267963
HumanCFTR1080cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
img OMIM, Score=1000, UMLKSK CUI: C0267963
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0267963Exocrine Pancreatic Insufficiency0self