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Details
Link-It Detail - Disease - Asthma in Children
Debug Stats
  • ### Total Build Time: 21 ms 27.448 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.146 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=5 ms Completed: 5 ms rowSize= 5.158 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 19.596 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Asthma in Children C0264408
Definition (1)

Asthma is a chronic disease that causes the airways - the tubes that carry air in and out of your lungs - to become sore and swollen. In the United States, about 20 million people have asthma. Nearly 9 million of them are children. Children have smaller airways than adults, which makes asthma especially serious for them. Children with asthma may experience wheezing, coughing, chest tightness and trouble breathing, especially early in the morning or at night.

Many things can cause asthma, including

  • Allergens - mold, pollen, animals
  • Irritants - cigarette smoke, air pollution
  • Weather - cold air, changes in weather
  • Exercise
  • Infections - flu, common cold

When asthma symptoms become worse than usual, it is called an asthma attack. Asthma is treated with two kinds of medicines: quick-relief medicines to stop asthma symptoms and long-term control medicines to prevent symptoms.

Relationships (10)

Relation Types:
diso_​to_​anat : 1
diso_​to_​chem : 1
diso_​to_​diso : 6
diso_​to_​phen : 2


Relationships:
associated_​with : 4
location_​of : 1
related_​to : 5
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATlocation_ofimg Bronchi C0006255
DISO_to_CHEMassociated_withimg Allergens C0002092
DISO_to_DISOrelated_toimg Abnormal breathing C1260922
DISO_to_DISOrelated_toimg Asthma C0004096
DISO_to_DISOassociated_withimg Dyspnea, Paroxysmal C0013405
DISO_to_DISOrelated_toimg Hypersensitivity C0020517
DISO_to_DISOassociated_withimg Spasm C0037763
DISO_to_DISOassociated_withimg Wheezing C0043144
DISO_to_PHENrelated_toimg Air Pollution C0001873
DISO_to_PHENrelated_toimg Air Pollution, Indoor C0085420
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanORMDL394103ORM1-like 3 (S. cerevisiae)
img GENERIF, Score=913, Pubmed Id: 18155279, UMLKSK CUI: C0264408
img GENERIF, Score=1000, Pubmed Id: 17611496, UMLKSK CUI: C0264408
HumanNOD110392nucleotide-binding oligomerization domain containing 1
img GENERIF, Score=1000, Pubmed Id: 15718249, UMLKSK CUI: C0264408
HumanTLR610333toll-like receptor 6
img GENERIF, Score=1000, Pubmed Id: 16188043, UMLKSK CUI: C0264408
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17450233, UMLKSK CUI: C0264408
HumanTLR47099toll-like receptor 4
img GENERIF, Score=911, Pubmed Id: 15356557, UMLKSK CUI: C0264408
HumanTGFB27042transforming growth factor, beta 2
img GENERIF, Score=913, Pubmed Id: 17651146, UMLKSK CUI: C0264408
HumanPAFAH1B15048platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
img GENERIF, Score=913, Pubmed Id: 11916011, UMLKSK CUI: C0264408
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=913, Pubmed Id: 16631427, UMLKSK CUI: C0264408
HumanIL133596interleukin 13
img GENERIF, Score=1000, Pubmed Id: 16461126, UMLKSK CUI: C0264408
HumanIL12B3593interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
img GENERIF, Score=868, Pubmed Id: 15356557, UMLKSK CUI: C0264408
HumanIL12A3592interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
img GENERIF, Score=868, Pubmed Id: 15356557, UMLKSK CUI: C0264408
HumanIL43565interleukin 4
img GENERIF, Score=1000, Pubmed Id: 15051937, UMLKSK CUI: C0264408
HumanIFNG3458interferon, gamma
img GAD, Score=858, Pubmed Id: 11240951, UMLKSK CUI: C0264408
HumanHLX3142H2.0-like homeobox
img GENERIF, Score=1000, Pubmed Id: 19038437, UMLKSK CUI: C0264408
HumanGSTP12950glutathione S-transferase pi 1
img GENERIF, Score=1000, Pubmed Id: 18335111, UMLKSK CUI: C0264408
HumanGSTM12944glutathione S-transferase mu 1
img GENERIF, Score=1000, Pubmed Id: 17643058, UMLKSK CUI: C0264408
HumanADRB2154adrenoceptor beta 2, surface
img GAD, Score=1000, Pubmed Id: 14610472, UMLKSK CUI: C0264408
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0264408Asthma in Children0self